Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Paul Tibbitts"'
Autor:
Sara Charmsaz, Éamon Hughes, Fiona T. Bane, Paul Tibbitts, Marie McIlroy, Christopher Byrne, Sinéad Cocchiglia, Jean McBryan, Bryan T. Hennessy, Róisín M. Dwyer, Michael J. Kerin, Arnold D. Hill, Leonie S. Young
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-12 (2017)
Abstract Background Endocrine therapy is standard treatment for estrogen receptor (ER)-positive breast cancer. However, its efficacy is limited by intrinsic and acquired resistance. Here the potential of S100β as a biomarker and inhibition of its si
Externí odkaz:
https://doaj.org/article/9038e261bbdf458cab6fb650bd3a2722
Autor:
Mohamed Zarog, Peter O’Leary, Miranda Kiernan, Jarlath Bolger, Paul Tibbitts, Stephen Coffey, Gerard Byrnes, Colin Peirce, Colum Dunne, Calvin Coffey
Publikováno v:
International Journal of Surgery. 109:343-351
Autor:
Leonie S. Young, Arnold D. Hill, Peadar Ó Gaora, Paul Tibbitts, Lance Hudson, Marie McIlroy, Jarlath Bolger, Christopher Byrne, Sinéad Cocchiglia, Damir Varešlija, Fiona T. Bane, Damian McCartan, Ailís Fagan, Jean McBryan
Purpose: Disease recurrence is a common problem in breast cancer and yet the mechanisms enabling tumor cells to evade therapy and colonize distant organs remain unclear. We sought to characterize global expression changes occurring with metastatic di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbc7d6aedde3ce445250ff33bb0db3f
https://doi.org/10.1158/1078-0432.c.6524784.v1
https://doi.org/10.1158/1078-0432.c.6524784.v1
Autor:
Leonie S. Young, Marie McIlroy, Arnold D.K. Hill, Peadar Ó Gaora, Yuan Hao, Ronán M. Conroy, Christopher Byrne, Paul Tibbitts, Fiona Bane, Jean McBryan, Damir Vareslija, Jane O'Hara
PDF file, 320KB, Supplementary Figures 1-9 Supplementary Figure 1: Expression levels of aromatase in our cell lines and aromatase activity assay Supplementary Figure 2: Proliferation of Aro and LetR in response to treatment Supplementary Figure 3: Ka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ae4d019c3ddc9c528331d39098517c
https://doi.org/10.1158/1078-0432.22452516.v1
https://doi.org/10.1158/1078-0432.22452516.v1
Autor:
Leonie S. Young, Marie McIlroy, Arnold D.K. Hill, Peadar Ó Gaora, Yuan Hao, Ronán M. Conroy, Christopher Byrne, Paul Tibbitts, Fiona Bane, Jean McBryan, Damir Vareslija, Jane O'Hara
PDF file, 14KB, Supplementary Table 1: Demographics of patients according to AIB1 status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7033b85867a5983bc5a3b37415f247e4
https://doi.org/10.1158/1078-0432.22452513
https://doi.org/10.1158/1078-0432.22452513
Autor:
Leonie S. Young, Arnold D. Hill, Peadar Ó Gaora, Paul Tibbitts, Lance Hudson, Marie McIlroy, Jarlath Bolger, Christopher Byrne, Sinéad Cocchiglia, Damir Varešlija, Fiona T. Bane, Damian McCartan, Ailís Fagan, Jean McBryan
Supplementary Table S4: Patient information for patients A-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21bdf3fa052f96df1a8830cdb71110ce
https://doi.org/10.1158/1078-0432.22461387.v1
https://doi.org/10.1158/1078-0432.22461387.v1
Autor:
Leonie S. Young, Marie McIlroy, Arnold D.K. Hill, Peadar Ó Gaora, Yuan Hao, Ronán M. Conroy, Christopher Byrne, Paul Tibbitts, Fiona Bane, Jean McBryan, Damir Vareslija, Jane O'Hara
Purpose: The use of aromatase inhibitors (AI) in the treatment of estrogen receptor (ER)-positive, postmenopausal breast cancer has proven efficacy. However, inappropriate activation of ER target genes has been implicated in the development of resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc4eab5b7dbbf42587e7338f1c78b3d
https://doi.org/10.1158/1078-0432.c.6522498.v1
https://doi.org/10.1158/1078-0432.c.6522498.v1
Autor:
Leonie S. Young, Arnold D. Hill, Peadar Ó Gaora, Paul Tibbitts, Lance Hudson, Marie McIlroy, Jarlath Bolger, Christopher Byrne, Sinéad Cocchiglia, Damir Varešlija, Fiona T. Bane, Damian McCartan, Ailís Fagan, Jean McBryan
Supplementary Figures S1-7. Supplementary Figure S1: Gene expression profiles of classic biomarkers in matched tumour samples from 3 patients. Supplementary Figure S2: Network map showing the enriched KEGG pathways from upregulated differentially exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4d4028e68a5503dd5599302e506aee
https://doi.org/10.1158/1078-0432.22461402
https://doi.org/10.1158/1078-0432.22461402
Autor:
Leonie S. Young, Marie McIlroy, Arnold D.K. Hill, Peadar Ó Gaora, Yuan Hao, Ronán M. Conroy, Christopher Byrne, Paul Tibbitts, Fiona Bane, Jean McBryan, Damir Vareslija, Jane O'Hara
PDF file, 55KB, Supplementary table 2: Rate of incidence of disease recurrence according to AIB1, HER2, tumour grade, tumour size and nodal status in breast cancer patients treated with first-line AI.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2fa66a0f00b5924029d167bd089e3b
https://doi.org/10.1158/1078-0432.22452510
https://doi.org/10.1158/1078-0432.22452510
Autor:
Leonie S. Young, Marie McIlroy, Arnold D.K. Hill, Peadar Ó Gaora, Yuan Hao, Ronán M. Conroy, Christopher Byrne, Paul Tibbitts, Fiona Bane, Jean McBryan, Damir Vareslija, Jane O'Hara
PDF file, 213KB, Supplementary Table 3b ER/AIB1 overlap genelist - partial ERE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b8193096e5cd1f7178710d25cda900
https://doi.org/10.1158/1078-0432.22452504.v1
https://doi.org/10.1158/1078-0432.22452504.v1