Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Paul Thomson"'
Autor:
Yeong Jer Lim, Victoria Ward, Liam Farrell, Dean Naisbitt, Anthony Brown, Eloise Phillips, Paul Thomson, Melanie Oates, Richard Jackson, Andrew Morrison, Matthew Burns, Paul Klenerman, Lance Turtle, Malcolm Rhodes, Kate Robinson, Simona Gatto, Moya Young, Toby A Eyre, David W. Eyre, Susanna Dunachie, Eleanor Barnes, Andrew Pettitt
Publikováno v:
HemaSphere, Vol 7, p e49729ac (2023)
Externí odkaz:
https://doaj.org/article/d9ee7f18db1b4bec986ec8ff1a35655e
Autor:
Ashley Robson, Morgan Trimble, Dominik Bauer, Andrew Loveridge, Paul Thomson, Guy Western, Peter Lindsey
Publikováno v:
Conservation Letters, Vol 15, Iss 1, Pp n/a-n/a (2022)
Abstract Calls to increase the global area under protection for conservation assume existing conservation areas are effective but, without adequate investment, they may not be. We collected survey data from expert respondents on perceived budgets, ma
Externí odkaz:
https://doaj.org/article/85e46d0271b04e5aa85157fad18a7c79
Autor:
Munir Pirmohamed, Anna Olsson-Brown, Lorenzo Ressel, Sean Hammond, Joshua Gardner, Serat-E Ali, Paul Thomson, Carol Jolly, Dan Carr, Dean Naisbitt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Many adverse reactions associated with immune checkpoint inhibitor (ICI) treatments are immunologically driven and may necessitate discontinuation of the ICI. Herein, we present a patient who had been administered the radio contrast media amidotrizoa
Externí odkaz:
https://doaj.org/article/c33e1c86d3af4bc089dc0ae8fb0773c3
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mitigating the risk of drug hypersensitivity reactions is an important facet of a given pharmaceutical, with poor performance in this area of safety often leading to warnings, restrictions and withdrawals. In the last 50 years, efforts to diagnose, m
Externí odkaz:
https://doaj.org/article/9c34bae6323342699aefe8a61f80373d
Autor:
Jirawat Pratoomwun, Paul Thomson, Kanoot Jaruthamsophon, Rawiporn Tiyasirichokchai, Pimonpan Jinda, Ticha Rerkpattanapipat, Wichittra Tassaneeyakul, Nontaya Nakkam, Pawinee Rerknimitr, Jettanong Klaewsongkram, Yuttana Srinoulprasert, Munir Pirmohamed, Dean J. Naisbitt, Chonlaphat Sukasem
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
HLA-B*13:01-positive patients in Thailand can develop frequent co-trimoxazole hypersensitivity reactions. This study aimed to characterize drug-specific T cells from three co-trimoxazole hypersensitive patients presenting with either Stevens-Johnson
Externí odkaz:
https://doaj.org/article/03d26c6a0de240ce8c0bfdad4c177587
Autor:
Daniel W.S. Challender, Michael't Sas-Rolfes, Gary W.J. Ades, Jason S.C. Chin, Nick Ching-Min Sun, Ju lian Chong, Ellen Connelly, Lisa Hywood, Sonja Luz, Rajesh K. Mohapatra, Paul de Ornellas, Keri Parker, Darren W. Pietersen, Scott I. Roberton, Gono Semiadi, Debbie Shaw, Chris R. Shepherd, Paul Thomson, Yifu Wang, Leanne Wicker, Shi Bao Wu, Helen C. Nash
Publikováno v:
Global Ecology and Conservation, Vol 20, Iss , Pp - (2019)
Pangolins are threatened by overexploitation for local and international use. They are subject to an international commercial trade ban, and are also the focus of other interventions, including attempts at commercial captive breeding. The impact that
Externí odkaz:
https://doaj.org/article/c9d83c7bcd504a5298b3653995d388c5
Autor:
Mubarak Almutairi, Adam Lister, Qing Zhao, James Line, Kareena Adair, Arun Tailor, James Waddington, Elsie Clarke, Joshua Gardner, Paul Thomson, Nicolas Harper, Yonghu Sun, Lele Sun, David A. Ostrov, Hong Liu, David J. MacEwan, Munir Pirmohamed, Xiaoli Meng, Furen Zhang, Dean J. Naisbitt
Publikováno v:
The Journal of Immunology. 210:1031-1042
Previous studies have shown that cysteine-reactive drug metabolites bind covalently with protein to activate patient T cells. However, the nature of the antigenic determinants that interact with HLA and whether T cell stimulatory peptides contain the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::540c34a1a67c694b21a19eb9c6f473f3
https://doi.org/10.4049/jimmunol.2200531
https://doi.org/10.4049/jimmunol.2200531
Publikováno v:
Clinical & Experimental Allergy. 52:1379-1390
Immune-mediated type IV adverse drug reactions are idiosyncratic in nature, generally not related to the primary or secondary pharmacology of the drug. Due to their complex nature and rarity, these iatrogenic reactions are seldom predicted or encount
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234192c3ef03290b22213dc409821ee9
https://doi.org/10.1111/cea.14235
https://doi.org/10.1111/cea.14235
Publikováno v:
Current opinion in allergy and clinical immunology. 22(4)
T-cell-mediated drug hypersensitivity is responsible for significant morbidity and mortality, and represents a substantial clinical concern. The purpose of this article is to focus on T-cell reactions and discuss recent advances in disease pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ad9ff3d1d5f259a5cb7265764eb225
https://pubmed.ncbi.nlm.nih.gov/35779063
https://pubmed.ncbi.nlm.nih.gov/35779063
Autor:
Christina Dold, Mariolina Salio, John Frater, Peter Simmonds, Christopher P. Conlon, J Slon-Campos, Z Yin, David I. Stuart, N F Schwabe, Guido C. Paesen, D Dong, Richard J. Cornall, Paul Thomson, T Lockett, Oliver W. Bayfield, U S Rajapaksa, J W Fry, P Supasa, Jonathan M. Grimes, R Levin, Wanwisa Dejnirattisai, Graham S. Ogg, Dannielle Wellington, Openshaw Pjm., Chen Y-L., Hawkins Dedp., P Zhang, Giorgio Napolitani, Tao Dong, J K Baillie, C Liu, Cesar Lopez-Camacho, Paul Sopp, M A Ansari, Alfred A. Antson, Ker D-S., Persephone Borrow, Susanna Dunachie, Andrew J. McMichael, Juthathip Mongkolsapaya, Yanchun Peng, B Wang, T Rostron, Shona C Moore, Lance Turtle, G Liu, T I de Silva, Krishanthi Subramaniam, Jeremy Ratcliff, Ho L-P., Benedikt M. Kessler, G Kerr, Yuguang Zhao, X Yao, Malcolm G Semple, Gavin R. Screaton, Paul Klenerman, Wayne Paes, R Jing, Alexander J. Mentzer, Y Zhang, Philip J. R. Goulder, Eleanor Barnes, Julian C. Knight
Publikováno v:
Nature Immunology
NATURE IMMUNOLOGY
Nat Immunol
NATURE IMMUNOLOGY
Nat Immunol
The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines and therapeutics will depend on understanding viral immunity. We studied T cell memory in 42 patients following recovery from COVID-19 (28 with mild disease and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f78680cf7c854968fa13a2ef61dd0a2
https://ora.ox.ac.uk/objects/uuid:e5e926ec-b256-4608-9956-84db12d56741
https://ora.ox.ac.uk/objects/uuid:e5e926ec-b256-4608-9956-84db12d56741
