Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Paul Tamburri"'
Autor:
Daniel Umbricht, Markus Abt, Paul Tamburri, Christopher Chatham, Štefan Holiga, Michael J. Frank, Anne G.E. Collins, David P. Walling, Rick Mofsen, Daniel Gruener, Lev Gertsik, Jeff Sevigny, Sanjay Keswani, Juergen Dukart
Publikováno v:
Biological Psychiatry Global Open Science, Vol 1, Iss 1, Pp 70-77 (2021)
Background: Reduced activation of dopamine D1 receptor signaling may be implicated in reward functioning as a potential driver of negative symptoms in schizophrenia. Phosphodiesterase 10A (PDE10A), an enzyme that is highly expressed in the striatum,
Externí odkaz:
https://doaj.org/article/4e96e9575d7248e086f19bdc0d374f88
Autor:
Stefan Holiga, Daniel Umbricht, Rick Mofsen, Markus Abt, Michael J. Frank, Juergen Dukart, Sanjay Keswani, Lev Gertsik, Christopher H. Chatham, Daniel Gruener, Jeff Sevigny, Anne G.E. Collins, David P. Walling, Paul Tamburri
Publikováno v:
Biological psychiatry 1(1), 70-77 (2021). doi:10.1016/j.bpsgos.2021.03.001
Biological Psychiatry Global Open Science, Vol 1, Iss 1, Pp 70-77 (2021)
Biological Psychiatry Global Open Science, Vol 1, Iss 1, Pp 70-77 (2021)
Background Reduced activation of dopamine D1 receptor signaling may be implicated in reward functioning as a potential driver of negative symptoms in schizophrenia. Phosphodiesterase 10A (PDE10A), an enzyme that is highly expressed in the striatum, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055794a1effef60fcc6fd99358a3cd1d
https://hdl.handle.net/2128/28586
https://hdl.handle.net/2128/28586
Autor:
Priya S. Kishnani, Jeannie Visootsak, Cesar Ochoa-Lubinoff, Nicole Bäumer, Brian G. Skotko, Xavier Liogier d'Ardhuy, Paul Tamburri, Maria-Clemencia Hernandez, Patrick Phuong, Sarah J. Hart, Gail A. Spiridigliozzi
Publikováno v:
American Journal of Medical Genetics Part A. 173:3029-3041
Although an increasing number of clinical trials have been developed for cognition in Down syndrome, there has been limited success to date in identifying effective interventions. This review describes the progression from pre-clinical studies with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2945fd8425093653b541489cbf69ade7
https://doi.org/10.1002/ajmg.a.38465
https://doi.org/10.1002/ajmg.a.38465
Autor:
Florian Lipsmeier, Daniel Umbricht, Atieh Bamdadian, Michael Lindenmann, Paul Tamburri, Wei-Yi Cheng
Publikováno v:
Schizophrenia Bulletin. 45:S194-S195
BACKGROUND: Quantified evaluation and continuous monitoring of behaviour and symptoms associated with negative symptoms of schizophrenia has been a challenge in clinical trials. Wearable sensor technology provides new opportunities to tackle these pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eadf53dd1145276eac6b6d1e6f41152
https://doi.org/10.1093/schbul/sbz021.259
https://doi.org/10.1093/schbul/sbz021.259
Autor:
Rick Mofsen, Lev Gertsik, Jürgen Dukart, Michael J. Frank, Daniel Umbricht, Anne G.E. Collins, Daniel Gruener, Paul Tamburri, David P. Walling, Christopher H. Chatham, Markus Abt, Jeffrey Sevigny
Publikováno v:
Schizophrenia Bulletin
Background The enzyme phosphodiesterase 10A (PDE10A) is highly expressed in the striatum where it modulates both dopamine D2 and D1 dependent signaling. Its inhibition leads to a suppression of D2 mediated signaling –similar to effects of D2 antago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756d2971653124d4957974f8624795d4
http://europepmc.org/articles/PMC5888501
http://europepmc.org/articles/PMC5888501
Autor:
Michael Rabbia, Ludger Banken, Luca Santarelli, Paulo Fontoura, Ulrich Beyer, Paul Tamburri, Jorge A. Quiroz, Dennis Deptula, Nikhat Parkar
Publikováno v:
JAMA Psychiatry. 73:675
Importance Antagonism of the postsynaptic metabotropic glutamate subtype 5 receptor is a novel approach to modulate glutamatergic function and has proven efficacy in a number of preclinical behavioral models of depression. Objective To evaluate the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d551727c9b9106ff65da375cf87b3cf2
https://doi.org/10.1001/jamapsychiatry.2016.0838
https://doi.org/10.1001/jamapsychiatry.2016.0838
Autor:
Paulo Fontoura, Jorge A. Quiroz, Paul Tamburri, Dennis Deptula, Ludger Banken, Luca Santarelli, Ulrich Beyer
Publikováno v:
European Neuropsychopharmacology. 24:S468
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcb481ff389a51e656a65efaed27f414
https://doi.org/10.1016/s0924-977x(14)70748-5
https://doi.org/10.1016/s0924-977x(14)70748-5