Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Paul T. Winnard"'
Autor:
Farhad Vesuna, Ivan Akhrymuk, Amy Smith, Paul T. Winnard, Shih-Chao Lin, Lauren Panny, Robert Scharpf, Kylene Kehn-Hall, Venu Raman
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
SARS-CoV-2, the virus behind the deadly COVID-19 pandemic, continues to spread globally even as vaccine strategies are proving effective in preventing hospitalizations and deaths. However, evolving variants of the virus appear to be more transmissive
Externí odkaz:
https://doaj.org/article/8955e83bf9ba4aa1a0372b40e904b979
Autor:
Saritha Tantravedi, Farhad Vesuna, Paul T. Winnard, Jr., Allison Martin, Michael Lim, Charles G. Eberhart, Cynthia Berlinicke, Eric Raabe, Paul J. van Diest, Venu Raman
Publikováno v:
Translational Oncology, Vol 12, Iss 1, Pp 96-105 (2019)
Medulloblastoma is the most common malignant tumor that arises from the cerebellum of the central nervous system. Clinically, medulloblastomas are treated by surgery, radiation, and chemotherapy, all of which result in toxicity and morbidity. Recent
Externí odkaz:
https://doaj.org/article/d6b70f7db6ee4f89a55ae33c6c6dc599
Autor:
Lu Jiang, Tiffany R. Greenwood, Dmitri Artemov, Venu Raman, Paul T. Winnard, Jr, Ron M.A. Heeren, Zaver M. Bhujwalla, Kristine Glunde
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 732-741 (2012)
Tumor hypoxia triggers signaling cascades that significantly affect biologic outcomes such as resistance to radiotherapy and chemotherapy in breast cancer. Hypoxic regions in solid tumor are spatially heterogeneous. Therefore, delineating the origin
Externí odkaz:
https://doaj.org/article/8f67675b93f54976b4675edd70dc3008
Autor:
Jacob E. Koskimaki, Emmanouil D. Karagiannis, Elena V. Rosca, Farhad Vesuna, Paul T. Winnard, Jr, Venu Raman, Zaver M. Bhujwalla, Aleksander S. Popel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 12, Pp 1285-1291 (2009)
Angiogenesis or neovascularization, the process of new blood vessel formation from preexisting microvasculature, involves interactions among several cell types including parenchymal, endothelial cells, and immune cells. The formation of new vessels i
Externí odkaz:
https://doaj.org/article/0b4aa86750db4e29a16eb8f76c5b66b7
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 10, Pp 796-806 (2006)
We have evaluated the use of the Xenogen IVIS 200 imaging system for real-time fluorescence protein- based optical imaging of metastatic progression in live animals. We found that green fluorescent protein- expressing cells (100 × 106) were not dete
Externí odkaz:
https://doaj.org/article/27be1a3801f944678792717555cb2057
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 4, Pp 250-258 (2006)
Homeobox protein HOXA5 functions as a transcriptional factor for genes that are not only involved in segmentation identity but also in cell differentiation. Although HOXA5 has been shown to regulate the expression of the tumor-suppressor protein p53,
Externí odkaz:
https://doaj.org/article/8b479d20ab5c41c6b21127e5c983b133
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242384 (2020)
BackgroundMonitoring and treating metastatic progression remains a formidable task due, in part, to an inability to monitor specific differential molecular adaptations that allow the cancer to thrive within different tissue types. Hence, to develop o
Externí odkaz:
https://doaj.org/article/46d04c32370e4b96a63d7e42415f39cc
Autor:
Zaver M. Bhujwalla, Anirban Maitra, Flonne Wildes, Yelena Mironchik, Radharani Marik, Marie-France Penet, Santosh K. Bharti, Paul T. Winnard
Supplemental Figure S1. Real time optical imaging after 4 weeks of To3B graft growth in the hind leg muscle of a nude mouse indicating that a tdT fluorescent signal was observed only after i.p. administration of 100 μg of DEX 24 hr prior to imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d621b182d586785ed7653b8eeda725
https://doi.org/10.1158/0008-5472.22410374.v1
https://doi.org/10.1158/0008-5472.22410374.v1
Autor:
Zaver M. Bhujwalla, Anirban Maitra, Flonne Wildes, Yelena Mironchik, Radharani Marik, Marie-France Penet, Santosh K. Bharti, Paul T. Winnard
The dire effects of cancer-induced cachexia undermine treatment and contribute to decreased survival rates. Therapeutic options for this syndrome are limited, and therefore efforts to identify signs of precachexia in cancer patients are necessary for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c842c3b12649c269808d9679db6386
https://doi.org/10.1158/0008-5472.c.6507977
https://doi.org/10.1158/0008-5472.c.6507977
Autor:
Venu Raman, Carlotta Glackin, Horst Burger, Paul Van Diest, Zaver Bhujwalla, Dmitri Artemov, Scott Kominsky, Arvind P. Pathak, Flonne Wildes, Yoshinori Kato, Farhad Vesuna, Paul T. Winnard, Yelena Mironchik
Aggressive cancer phenotypes are a manifestation of many different genetic alterations that promote rapid proliferation and metastasis. In this study, we show that stable overexpression of Twist in a breast cancer cell line, MCF-7, altered its morpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226764eb56bf3ab6eb3158891a2d6503
https://doi.org/10.1158/0008-5472.c.6494051
https://doi.org/10.1158/0008-5472.c.6494051