Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Paul T. Wan"'
Autor:
Hongwei Guo, Luca Martinelli, Helen Boyd, Titia K. Sixma, Athanassios Adamopoulos, Paul T. Wan, Jenny Gunnarsson, Patrik Johansson, Noam Zelcer
Publikováno v:
Journal of biological chemistry, 295(39), 13570-13583. American Society for Biochemistry and Molecular Biology Inc.
'Journal of Biological Chemistry ', vol: 295, pages: 13570-13583 (2020)
The Journal of Biological Chemistry
'Journal of Biological Chemistry ', vol: 295, pages: 13570-13583 (2020)
The Journal of Biological Chemistry
Hepatic abundance of the low-density lipoprotein receptor (LDLR) is a critical determinant of circulating plasma LDL cholesterol levels and hence development of coronary artery disease. The sterol-responsive E3 ubiquitin ligase inducible degrader of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279f65bf4135136f62146d04a9c1d08c
https://pure.amc.nl/en/publications/structural-analysis-of-the-ldl-receptorinteracting-ferm-domain-in-the-e3-ubiquitin-ligase-idol-reveals-an-obscured-substratebinding-site(d4e66d09-c066-40a4-9abe-02d22f591f1e).html
https://pure.amc.nl/en/publications/structural-analysis-of-the-ldl-receptorinteracting-ferm-domain-in-the-e3-ubiquitin-ligase-idol-reveals-an-obscured-substratebinding-site(d4e66d09-c066-40a4-9abe-02d22f591f1e).html
Autor:
Eilidh K. Leitch, Paul T. Wan, Göran Dahl, Maria Fridén-Saxin, Helen Boyd, Ali Tavassoli, Garry Pairaudeau, Eric Valeur, Nagarajan Elumalai, Paul Clarkson
Publikováno v:
Chemical Science
A cyclic peptide IDOL homodimerization inhibitor identified from a genetically encoded SICLOPPS library is active in vitro and in cells.
Cellular uptake of circulating cholesterol occurs via the low density lipoprotein receptor (LDLR). The E3 ub
Cellular uptake of circulating cholesterol occurs via the low density lipoprotein receptor (LDLR). The E3 ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f9d8ae83264b610bb9a793f561f9a5
https://eprints.soton.ac.uk/421740/
https://eprints.soton.ac.uk/421740/
Publikováno v:
Current Opinion in Structural Biology. 23:393-402
Protein production for structural and biophysical studies, functional assays, biomarkers, mechanistic studies in vitro and in vivo, but also for therapeutic applications in pharma, biotech and academia has evolved into a mature discipline in recent y
Autor:
Per Hillertz, Fritz Schweikart, Lisa Wissler, Yanlong Zhao, Paul T. Wan, Niek Dekker, Yafeng Xue
Publikováno v:
ChemMedChem. 8(11)
Tau-tubulin kinase 1 (TTBK1) is a serine/threonine/tyrosine kinase that putatively phosphorylates residues including S422 in tau protein. Hyperphosphorylation of tau protein is the primary cause of tau pathology and neuronal death associated with Alz
Autor:
Paul T. Wan, Niek Dekker, Per Hillertz, Yanlong Zhao, Fritz Schweikart, Yafeng Xue, Lisa Wissler
Publikováno v:
ChemMedChem. 8:1721-1721
Publikováno v:
International Journal of Corrosion, Vol 2010 (2010)
The understanding of how corrosion affects magnesium alloys is of utmost importance as the automotive and aerospace industries have become interested in the use of these lightweight alloys. However, the standardized salt-spray test does not produce a
Externí odkaz:
https://doaj.org/article/c3efa2a5ae1d4038bb0a2d1bbb524a4c