Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paul T. Toran"'
Autor:
Brian M. Barth, Weiyuan Wang, Paul T. Toran, Todd E. Fox, Charyguly Annageldiyev, Regina M. Ondrasik, Nicole R. Keasey, Timothy J. Brown, Viola G. Devine, Emily C. Sullivan, Andrea L. Cote, Vasiliki Papakotsi, Su-Fern Tan, Sriram S. Shanmugavelandy, Tye G. Deering, David B. Needle, Stephan T. Stern, Junjia Zhu, Jason Liao, Aaron D. Viny, David J. Feith, Ross L. Levine, Hong-Gang Wang, Thomas P. Loughran, Jr, Arati Sharma, Mark Kester, David F. Claxton
Publikováno v:
Blood Advances, Vol 3, Iss 17, Pp 2598-2603 (2019)
Externí odkaz:
https://doaj.org/article/c4625d35b02b4dee8bf8588d9b18b16d
Autor:
Charyguly Annageldiyev, Nicole R. Keasey, Emily Sullivan, Paul T. Toran, Hong Gang Wang, Regina M. Ondrasik, Su Fern Tan, Andrea L. Cote, Tye G. Deering, Todd E. Fox, David J. Feith, Brian M. Barth, Timothy J Brown, Stephan T. Stern, Mark Kester, David F. Claxton, Thomas P. Loughran, Vasiliki Papakotsi, Arati Sharma, Ross L. Levine, David B. Needle, Junjia Zhu, Sriram S. Shanmugavelandy, Aaron D. Viny, Viola Devine, Weiyuan Wang, Jason Liao
Publikováno v:
Blood Advances. 3:2598-2603
Key Points Distinct sphingolipid metabolism of AML with MDS-related changes defines unique sensitivity to nanoliposomal C6-ceramide. Vinblastine alters sphingolipid metabolism to enhance the sensitivity of AML to nanoliposomal C6-ceramide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8cba30af3fa7af31a794e18295fa76
https://doi.org/10.1182/bloodadvances.2018021295
https://doi.org/10.1182/bloodadvances.2018021295
Publikováno v:
Exp Hematol
As important vectors for ectopic protein expression, gene silencing, and progenitor cell barcoding, lentiviruses continue to emerge as versatile research and clinical tools. For studies employing cell types that are relatively resistant to transducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17eb7204bda76b455b4b333e5a6bacb2
https://europepmc.org/articles/PMC7372909/
https://europepmc.org/articles/PMC7372909/
Autor:
Paul T. Toran, Vladislav B. Bergo, Jeffrey C. Silva, Ghaith M. Hamza, M. Paola Castaldi, Camilla R. Worsfold, Don M. Wojchowski, Sergey Mamaev
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2016 (2020)
Volume 21
Issue 6
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2016 (2020)
Volume 21
Issue 6
The ability to quantitatively probe diverse panels of proteins and their post-translational modifications (PTMs) across multiple samples would aid a broad spectrum of biological, biochemical and pharmacological studies. We report a novel, microarray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c238965a28ed015514d9925b57e35a
http://europepmc.org/articles/PMC7139916
http://europepmc.org/articles/PMC7139916
Publikováno v:
International journal of biopharmaceutical sciences. 1(2)
Sphingolipids represent one of the major classes of bioactive lipids. Studies of sphingolipids have intensified in the past several years, revealing their roles in nearly all cell biological processes. In addition, epigenetic regulation has gained su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4221487090f383b29f3387e5e885c617
https://pubmed.ncbi.nlm.nih.gov/30637412
https://pubmed.ncbi.nlm.nih.gov/30637412
Autor:
Colin M, McGill, Timothy J, Brown, Yuan-Yin, Cheng, Lindsey N, Fisher, Sriram S, Shanmugavelandy, Sally J, Gustafson, Kriya L, Dunlap, Mary Ann, Lila, Mark, Kester, Paul T, Toran, David F, Claxton, Brian M, Barth
Publikováno v:
International journal of biopharmaceutical sciences. 1(1)
Acute myeloid leukemia (AML) is an aggressive hematological malignancy with high incidence in the aging population. In addition, AML is one of the more common pediatric malignancies. Unfortunately, both of these patient groups are quite sensitive to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b82efc712f3e858aa5cc92153097397f
https://pubmed.ncbi.nlm.nih.gov/29607443
https://pubmed.ncbi.nlm.nih.gov/29607443
Autor:
Brian M. Barth, Emily Sullivan, Thomas P. Loughran, Vasiliki Papakotsi, Sarah R. Walker, Paul T. Toran, Weiyuan Wang, Andrea L. Cote
Publikováno v:
Blood. 134:1700-1700
Myelodysplastic syndrome (MDS) is a clonal hematopoietic disorder characterized by ineffective hematopoiesis, cytopenias, and an increased risk of transformation to acute myeloid leukemia. New studies are urgently needed to understand the underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d096c3db0624517cfbe3864a4b6ce09
https://doi.org/10.1182/blood-2019-131623
https://doi.org/10.1182/blood-2019-131623
Autor:
Weiyuan Wang, Paul T. Toran, Vasiliki Papakotsi, Andrea L. Cote, Emily Sullivan, Brian M. Barth, Thomas P. Loughran
Publikováno v:
Blood. 134:1245-1245
BACKGROUND: Mutations to epigenetic and spliceosome regulators frequently occur in acute myeloid leukemia (AML) and contribute to the underlying pathobiology of the disease. In addition, recent studies have sought to improve the anti-AML efficacy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1250803bd1a665aa1f2a09b2eba0240d
https://doi.org/10.1182/blood-2019-130964
https://doi.org/10.1182/blood-2019-130964
SummaryHemochromatosis is caused by mutations in HFE, a protein that competes with transferrin (TF) for binding to transferrin receptor 1 (TFR1). We developed mutant mouse strains to gain insight into the role of the Hfe/Tfr1 complex in regulating ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6906444418748ce23d036ed58a3b7f8
https://resolver.caltech.edu/CaltechAUTHORS:20170327-141608645
https://resolver.caltech.edu/CaltechAUTHORS:20170327-141608645
Publikováno v:
Blood. 108:267-267
Hemochromatosis is a common genetic disease resulting from increased dietary iron absorption and tissue iron deposition. Mutations in five unrelated genes are known to cause hemochromatosis in humans and mice. These encode the classic hemochromatosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40f706deb69a2031b414c59e67f93cc4
https://doi.org/10.1182/blood.v108.11.267.267
https://doi.org/10.1182/blood.v108.11.267.267