Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Paul T Salo"'
Autor:
Aisha S Ahmed, Jian Li, Alim M D Abdul, Mahmood Ahmed, Claes-Göran Östenson, Paul T Salo, Carolyn Hewitt, David A Hart, Paul W Ackermann
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170748 (2017)
Metabolic diseases such as diabetes mellitus type-II (DM-II) may increase the risk of suffering painful connective tissue disorders and tendon ruptures. The pathomechanisms, however, by which diabetes adversely affects connective tissue matrix metabo
Externí odkaz:
https://doaj.org/article/4b2751cf2469423a8c620fc27409a89a
Autor:
Manmeet S. Dhiman, Taylor J. Bader, Dragana Ponjevic, Paul T. Salo, David A. Hart, Ganesh Swamy, John R. Matyas, Neil A. Duncan
Publikováno v:
JOR Spine, Vol 7, Iss 3, Pp n/a-n/a (2024)
Abstract Introduction Degenerative disc disease (DDD) is accompanied by structural changes in the intervertebral discs (IVD). Extra‐cellular matrix degradation of the annulus fibrosus (AF) has been linked with degeneration of the IVD. Collagen is a
Externí odkaz:
https://doaj.org/article/436a730e48364e9ca1ce1b9893c9a13f
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131661 (2015)
Articular cartilage has been the focus of multiple strategies to improve its regenerative/ repair capacity. The Murphy Roths Large (MRL/MpJ) "super-healer" mouse demonstrates an unusual enhanced regenerative capacity in many tissues and provides an o
Externí odkaz:
https://doaj.org/article/39bf43979a78482dbc2e9b1ac917354b
Autor:
Roman J. Krawetz, Saleem Abubacker, Catherine Leonard, Anand O. Masson, Sophia Shah, Nadia Narendran, Pankaj Tailor, Suresh C. Regmi, Elodie Labit, Nicoletta Ninkovic, Jessica May Corpuz, Kenichi Ito, T. Michael Underhill, Paul T. Salo, Tannin A. Schmidt, Jeff A. Biernaskie
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-18 (2022)
Abstract The wound healing response is one of most primitive and conserved physiological responses in the animal kingdom, as restoring tissue integrity/homeostasis can be the difference between life and death. Wound healing in mammals is mediated by
Externí odkaz:
https://doaj.org/article/6cfd5dea43f0478bbcc1d17da0a3891f
Autor:
Prism S. Schneider, MD, PhD, FRCSC, Herman Johal, MD, MSc, FRCSC, A. Dean Befus, PhD, Paul T. Salo, MD, FRCSC, David A. Hart, PhD, Kevin A. Hildebrand, MD, FRCSC
Publikováno v:
JBJS Open Access, Vol 6, Iss 1 (2021)
Background:. Posttraumatic joint contracture is a debilitating complication following an acute fracture or intra-articular injury that can lead to loss of motion and an inability to complete activities of daily living. In prior studies using an estab
Externí odkaz:
https://doaj.org/article/b882bd4c03084b89beda63bb7ba9452c
Autor:
Sathvika Mudigonda, Sophia Shah, Nabangshu Das, Jessica May Corpuz, Nicoletta Ninkovic, Nedaa Al-Jezani, T. Michael Underhill, Paul T. Salo, Alim P. Mitha, Frank G. Lyons, Roger Cho, Tannin A. Schmidt, Antoine Dufour, Roman J. Krawetz
Publikováno v:
Cell and Tissue Research. 389:483-499
Publikováno v:
Advanced biology.
Epidural fat contains a population of mesenchymal progenitor cells (MPCs), and this study explores the behavior of these cells on the adjacent dura mater during growth and in response to injury in a p21 knockout mouse model. p21
Autor:
Roman J. Krawetz, Yiru Elizabeth Wu, Karri L. Bertram, Anchita Shonak, Anand O. Masson, Guomin Ren, Catherine Leonard, Mohit Kapoor, John R. Matyas, Paul T. Salo
Publikováno v:
Cell Death & Disease. 13
Aggrecan is a critical component of the extracellular matrix of all cartilages. One of the early hallmarks of osteoarthritis (OA) is the loss of aggrecan from articular cartilage followed by degeneration of the tissue. Mesenchymal progenitor cell (MP
Autor:
Prism S. Schneider, Paul T. Salo, Halli Krzyzaniak, Marc Carrier, Leslie Skeith, Daniel You, Paul E. Ronksley, Robert Korley, Brett Ponich, Yan Xu
Publikováno v:
Journal of Thrombosis and Haemostasis. 18:2566-2581
Background Hip fracture patients on oral anticoagulants (OACs) experience increased time-to-surgery and higher mortality compared to non-anticoagulated patients. However, it is unclear whether pre-injury OAC status and its associated operative delay
Autor:
Crystal Sixian Liu, Alexandra Garven, Michaela Kopka, A. Dean Befus, Ayoola Ademola, Paul T. Salo, David A. Hart, Mei Zhang, Kevin A. Hildebrand
Publikováno v:
Journal of Orthopaedic Research. 38:2015-2019
Mast cells contain an abundance of tryptase, and preclinical models have shown elevated serum mast cell tryptase (SMCT) in the setting of posttraumatic joint contractures. Therefore, SMCT emerged as a potential biomarker to help recognize patients wi