Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Paul T Loughna"'
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7393 (2009)
BACKGROUND: Obesity invokes a range of metabolic disturbances, but the transition from a poor to excessive nutritional environment may exacerbate adult metabolic dysfunction. The current study investigated global maternal nutrient restriction during
Externí odkaz:
https://doaj.org/article/2648a806e16d478d885bd024ac88472c
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Phosphoenolpyruvate carboxykinase (PEPCK) is a gluconeogenic enzyme with a cytosolic (Pck1/PEPCK-C) and mitochondrial (Pck2/PEPCK-M) isoform. Here we investigate the effect of 3-mercaptopicolinic acid (3-MPA), a PEPCK inhibitor, on C2C12 mus
Externí odkaz:
https://doaj.org/article/700ab5aa868d43ae891ddb46d418f63a
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100924- (2021)
Myosin heavy chain-IIB (MyHC-IIB; encoded by MYH4 or Myh4) expression is often associated with muscle hypertrophic growth. Unlike other large mammals, domestic pig breeds express MyHC-IIB at both the mRNA and protein level. Aim: To utilise a fluoresc
Externí odkaz:
https://doaj.org/article/e247c00942fe4dd6a3cce99cc8c86ce6
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss, Pp 100924-(2021)
Myosin heavy chain-IIB (MyHC-IIB; encoded by MYH4 or Myh4) expression is often associated with muscle hypertrophic growth. Unlike other large mammals, domestic pig breeds express MyHC-IIB at both the mRNA and protein level. Aim To utilise a fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec85d207eb24ac2028de3e0b6d08035
http://www.sciencedirect.com/science/article/pii/S2405580821000182
http://www.sciencedirect.com/science/article/pii/S2405580821000182
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Phosphoenolpyruvate carboxykinase (PEPCK) is a gluconeogenic enzyme with a cytosolic (Pck1/PEPCK-C) and mitochondrial (Pck2/PEPCK-M) isoform. Here we investigate the effect of 3-mercaptopicolinic acid (3-MPA), a PEPCK inhibitor, on C2C12 muscle cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318b099a6fa1fb1d87d51676966555ef
https://doi.org/10.1038/s41598-020-79324-9
https://doi.org/10.1038/s41598-020-79324-9
Publikováno v:
Biochemistry and Biophysics Reports
Myosin heavy chain-IIB (MyHC-IIB; encoded by MYH4 or Myh4) expression is often associated with muscle hypertrophic growth. Unlike other large mammals, domestic pig breeds express MyHC-IIB at both the mRNA and protein level. Aim To utilise a fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::101250141a9fe02a39a8827c596334bb
https://pubmed.ncbi.nlm.nih.gov/33614996
https://pubmed.ncbi.nlm.nih.gov/33614996
Publikováno v:
Biochemistry and Biophysics Reports, Vol 20, Iss, Pp-(2019)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Skeletal muscle is a highly metabolic and dynamic tissue that is formed through the complex and well-organised process of myogenesis. Although there is a good understanding about the role of the Muscle Regulatory Factors during myogenesis, little is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9486afa2e57107b1647995b9d40eac
http://www.sciencedirect.com/science/article/pii/S2405580819300263
http://www.sciencedirect.com/science/article/pii/S2405580819300263
Publikováno v:
Differentiation. 88:117-123
Aging is associated with a gradual loss of skeletal muscle mass and an impaired ability of this tissue to compensate for trauma. Studies in rodents and humans have also shown that resident stem cells within muscle have a reduced ability to proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bdd89156735cf1d811da5323ebe1f4
https://doi.org/10.1016/j.diff.2014.12.001
https://doi.org/10.1016/j.diff.2014.12.001
Autor:
Derek Samuel Hill, Leigh Breen, Nathaniel J. Szewczyk, Kenneth Smith, Paul T. Loughna, Philip J. Atherton, Stuart M. Phillips, Tyler A. Churchward-Venne, Hannah Crossland, John A. Rathmacher, Daniel J. Wilkinson, T. Hossain, Bethan E. Phillips, John P. Williams, Timothy Etheridge
Publikováno v:
The Journal of Physiology
Maintenance of skeletal muscle mass is contingent upon the dynamic equilibrium (fasted losses-fed gains) in protein turnover. Of all nutrients, the single amino acid leucine (Leu) possesses the most marked anabolic characteristics in acting as a trig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a402e0885359d6f5cb2472a165e24ea
https://doi.org/10.1113/jphysiol.2013.253203
https://doi.org/10.1113/jphysiol.2013.253203
Autor:
Zoe Redshaw, Paul T. Loughna
Publikováno v:
Differentiation. 84(2):193-202
The physiological oxygen concentration of many tissues is far lower than that in which cells are typically cultured in vitro and this may inadvertently influence the proliferation and differentiation potential of many cell types. Muscle derived stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bbf0ae13757ff474022e5f37848cbb