Výsledky vyhledávání - "Paul T, Manser"

Akademický článek

Evaluation of partial volume correction and analysis of longitudinal [18F]GTP1 tau PET imaging in Alzheimer's disease using linear mixed-effects models

Autor: Sandra M. Sanabria Bohórquez, Suzanne Baker, Paul T. Manser, Matteo Tonietto, Christopher Galli, Kristin R. Wildsmith, Yixuan Zou, Geoffrey A. Kerchner, Robby Weimer, Edmond Teng

Publikováno v: Frontiers in Neuroimaging, Vol 3 (2024)

PurposeWe evaluated the impact of partial volume correction (PVC) methods on the quantification of longitudinal [18F]GTP1 tau positron-emission tomography (PET) in Alzheimer's disease and the suitability of describing the tau pathology burden tempora

Externí odkaz: https://doaj.org/article/935c608a68ca4a409b94bd58178354e4

Zobrazit plný text záznamu

Akademický článek

Cross‐sectional and longitudinal assessments of function in prodromal‐to‐mild Alzheimer's disease: A comparison of the ADCS‐ADL and A‐IADL‐Q scales

Autor: Edmond Teng, Yihao Li, Paul T. Manser, Karen Pickthorn, Brandon D. Butcher, Mira Blendstrup, Christopher Randolph, Sietske A.M. Sikkes

Publikováno v: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)

Abstract Introduction Prior observational work in a heterogeneous cohort of participants with mild cognitive impairment suggests the Amsterdam Instrumental Activities of Daily Living Questionnaire (A‐IADL‐Q) may have greater sensitivity for funct

Externí odkaz: https://doaj.org/article/64cf9cd5a258479abdd3af08cbaf2c77

Zobrazit plný text záznamu

Akademický článek

Baseline [18F]GTP1 tau PET imaging is associated with subsequent cognitive decline in Alzheimer’s disease

Autor: Edmond Teng, Paul T. Manser, Sandra Sanabria Bohorquez, Kristin R. Wildsmith, Karen Pickthorn, Suzanne L. Baker, Michael Ward, Geoffrey A. Kerchner, Robby M. Weimer

Publikováno v: Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2021)

Abstract Background The role and implementation of tau PET imaging for predicting subsequent cognitive decline in Alzheimer’s disease (AD) remains uncertain. This study was designed to evaluate the relationship between baseline [18F]GTP1 tau PET an

Externí odkaz: https://doaj.org/article/151ea849eff2427ead44ea9980aa2f28

Zobrazit plný text záznamu

Safety and Efficacy of Semorinemab in Individuals with Prodromal to Mild Alzheimer Disease

Autor: Edmond, Teng, Paul T, Manser, Karen, Pickthorn, Flavia, Brunstein, Mira, Blendstrup, Sandra, Sanabria Bohorquez, Kristin R, Wildsmith, Bali, Toth, Michael, Dolton, Vidya, Ramakrishnan, Ashwini, Bobbala, Sietske A M, Sikkes, Michael, Ward, Reina N, Fuji, Geoffrey A, Kerchner, David, Weisman

Publikováno v: JAMA Neurology, 79(8), 758-767. American Medical Association
Teng, E, Manser, P T, Pickthorn, K, Brunstein, F, Blendstrup, M, Sanabria Bohorquez, S, Wildsmith, K R, Toth, B, Dolton, M, Ramakrishnan, V, Bobbala, A, Sikkes, S A M, Ward, M, Fuji, R N & Kerchner, G A 2022, ' Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease : A Randomized Clinical Trial ', JAMA Neurology, vol. 79, no. 8, pp. 758-767 . https://doi.org/10.1001/jamaneurol.2022.1375
Teng, E, Manser, P T, Pickthorn, K, Brunstein, F, Blendstrup, M, Sanabria Bohorquez, S, Wildsmith, K R, Toth, B, Dolton, M, Ramakrishnan, V, Bobbala, A, Sikkes, S A M, Ward, M, Fuji, R N & Kerchner, G A 2022, ' Safety and Efficacy of Semorinemab in Individuals with Prodromal to Mild Alzheimer Disease : A Randomized Clinical Trial ', JAMA Neurology, vol. 79, no. 8, pp. 758-767 . https://doi.org/10.1001/jamaneurol.2022.1375

Importance: Neurofibrillary tangles composed of aggregated tau protein are one of the neuropathological hallmarks of Alzheimer disease (AD) and correlate with clinical disease severity. Monoclonal antibodies targeting tau may have the potential to am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5221ef4dd6e70490909446ed6b1ce80
http://www.scopus.com/inward/record.url?scp=85132835366&partnerID=8YFLogxK

Zobrazit plný text záznamu

Site-Specific Cerebrospinal Fluid Tau Hyperphosphorylation in Response to Alzheimer’s Disease Brain Pathology: Not All Tau Phospho-Sites are Hyperphosphorylated

Autor: Kristin R. Wildsmith, Randall J. Bateman, Paul T. Manser, Balazs Toth, Sandra M. Sanabria-Bohórquez, Nicolas R. Barthélemy, Michael Keeley, Edmond Teng, Robby M. Weimer

Publikováno v: Journal of Alzheimer's Disease. 85:415-429

Background: Understanding patterns of association between CSF phosphorylated tau (p-tau) species and clinical disease severity will aid Alzheimer’s disease (AD) diagnosis and treatment. Objective: To evaluate changes in tau phosphorylation ratios t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a0bea7962fd4765cc9818dc811bda4
https://doi.org/10.3233/jad-210677

Zobrazit plný text záznamu

Baseline [18F]GTP1 tau PET imaging is associated with subsequent cognitive decline in Alzheimer’s disease

Autor: Kristin R. Wildsmith, Geoffrey A. Kerchner, Michael Ward, Edmond Teng, Paul T. Manser, Suzanne L. Baker, Karen Pickthorn, Sandra Sanabria Bohorquez, Robby M. Weimer

Publikováno v: Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2021)
Alzheimer's research & therapy, vol 13, iss 1
Alzheimer's Research & Therapy

Background The role and implementation of tau PET imaging for predicting subsequent cognitive decline in Alzheimer’s disease (AD) remains uncertain. This study was designed to evaluate the relationship between baseline [18F]GTP1 tau PET and subsequ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9dfe74821e4dd458e22a73b8d8a8999
https://doaj.org/article/151ea849eff2427ead44ea9980aa2f28

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání