Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Paul Szewczyk"'
Autor:
Daniel Conde, Brianna Miles, Derek R. Drost, Norman J. Wickett, Matias Kirst, Christina A. Finegan, Matthew G. Johnson, Paul Szewczyk, Geoffrey Chang, Henry W. Schmidt, Timothy A. Martin, Christopher Dervinis, Gary F. Peter, Faride Unda, J. Gordon Burleigh, Carlos A. Gonzalez-Benecke, Shawn D. Mansfield, Aaron P. McGrath, Cíntia L. Ribeiro, Evandro Novaes, Kelly M. Balmant
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Flowering plants exhibit exceptional diversity of form and stature. Their ability to achieve great heights is supported in part by their water-conducting specialized cells, the vessel elements, which have gradually evolved and resulted i
Autor:
Rupak Doshi, Miguel A. Piñeros, Denisse Garza, Geoffrey Chang, Paul Szewczyk, Aaron P. McGrath, Leon V. Kochian
Publikováno v:
Scientific reports, vol 7, iss 1
BASE-Bielefeld Academic Search Engine
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
BASE-Bielefeld Academic Search Engine
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
About 50% of the world’s arable land is strongly acidic (soil pH < 5). The low pH of these soils solubilizes root-toxic ionic aluminium (Al3+) species from clay minerals, driving the evolution of various counteractive adaptations in cultivated crop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfa9a286266a22e38a4113c6b7e5a5f
https://escholarship.org/uc/item/69d5x7k3
https://escholarship.org/uc/item/69d5x7k3
Publikováno v:
Science. 312:741-744
EmrD is a multidrug transporter from the Major Facilitator Superfamily that expels amphipathic compounds across the inner membrane of Escherichia coli . Here, we report the x-ray structure of EmrD determined to a resolution of 3.5 angstroms. The stru
Autor:
Steven D. Rees, Paul Szewczyk, Aaron P. McGrath, Geoffrey Chang, Sung Chang Lee, Houchao Tao, Ina L. Urbatsch, Rupak Doshi, Mark Villaluz, Qinghai Zhang
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
Co-crystal structures of P-glycoprotein with a series of engineered ligands reveal multiple ligand-binding modes, a ligand-binding site on the outer surface of the transporter and a conformational change that may couple to ATP hydrolysis.
P-glyc
P-glyc
Autor:
Chang-Wook Lee, Alexandra Caya, Cristina Cregger, Els Pardon, Mark Villaluz, Pierre Falson, Vinciane Grimard, Geoffrey Chang, Jan Steyaert, Paul Szewczyk, Rupak Doshi, Cédric Govaerts, Douglas J. Swartz, Andrew B. Ward, Ina L. Urbatsch, Lorena Martinez
P-glycoprotein (P-gp) is one of the best-known mediators of drug efflux-based multidrug resistance in many cancers. This validated therapeutic target is a prototypic, plasma membrane resident ATP-Binding Cassette transporter that pumps xenobiotic com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623c2fd26b762bddc3a5a19a491ff993
https://doi.org/10.1073/pnas.1309275110
https://doi.org/10.1073/pnas.1309275110
Autor:
Qinghai Zhang, Xiao He, Paul Szewczyk, Mariah Evin, Geoffrey Chang, Wen-Xu Hong, Andrey Karyakin
Transporter proteins from the MATE (multidrug and toxic compound extrusion) family are involved in metabolite transport in plants and in multidrug resistance in bacteria and mammals. MATE transporters were the only remaining class of multidrug resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114d17bec257bae9e5cd86e373dcd238
https://europepmc.org/articles/PMC3152480/
https://europepmc.org/articles/PMC3152480/
Autor:
Barry Silverstein, Stephen R. Waltman, Martha G. Farber, Bernard Becker, Brad Koloms, Paul Szewczyk, Theodore Krupin
Publikováno v:
Archives of ophthalmology (Chicago, Ill. : 1960). 100(4)
• Fluorophotometry was used to evaluate the blood-ocular barrier in rats following streptozocin-induced diabetes, experimental systemic hypertension, sodium iodate treatment, diet-induced galactosemia, and aldose reductase inhibitors. After adminis