Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Paul Stoppie"'
Autor:
Paul Stoppie, Yvan Vander Heyden, Samuel Bodé, Bram Baert, Jo Lambert, Guido Slegers, Eric Deconinck, Mireille Van Gele, Johan Beetens, Marián Slodička, Bart De Spiegeleer
Publikováno v:
Ghent University Academic Bibliography
Vrije Universiteit Brussel
Vrije Universiteit Brussel
A set of 116 structurally very diverse compounds, mainly drugs, was characterized by 1630 molecular descriptors. The biological property modelled in this study was the transdermal permeability coefficient log K p . The main objective was to find a li
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 3:475-478
Background Itraconazole is an orally active antifungal lipophilic drug with high affinity for sebum and keratinocytes. Aim The aim of the study was to investigate the routes of percutaneous egression and the sites of cutaneous action/storage of 3H-la
Autor:
Yves Poumay, Séverine Giltaire, Paul Stoppie, Françoise Herphelin, Michel Hérin, Aurélie Frankart
Publikováno v:
Giltaire, S, Herphelin, F, Frankart, A, Herin, M, Stoppie, P & Poumay, Y 2009, ' The CYP26 inhibitor R115866 potentiates the effects of all-trans-retinoic acid on cultured human epidermal keratinocytes ', British Journal of Dermatology, vol. 160, pp. 505-513 .
University of Namur
University of Namur
Summary Background All-trans retinoic acid (RA) is known to regulate keratinocyte proliferation and differentiation, and retinoids are used as therapeutic agents in certain dermatological disorders, such as psoriasis and acne. Epidermal expression of
Autor:
Didier de Chaffoy, Gustaaf Maria Boeckx, Gaston Stanislas Marcella Diels, Pedro Pardal Martínez, Davy Petrus Franciscus Maria Petit, Jean Pierre Frans Van Wauwe, Fred De Clerck, Marina Lucie Louise Cools, Anton Megens, José Manuel Alonso, Javier Fernández, Danielle Peeters, Adolfo Dı́az, Paul Stoppie, Laura Iturrino, Marijke Somers, F. Deroose, J. Ignacio Andres, Eddy Jean Edgard Freyne, Encarna Matesanz
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(4)
This communication describes the synthesis and in vitro PDE4 inhibitory activity of a novel series of imidazol-2-one and 2-cyanoiminoimidazole derivatives. The compounds described were also tested in in vivo models to evaluate their anti-inflammatory
Publikováno v:
Neurochemical research. 9(10)
A thermostable alpha 2 globulin inhibiting the immunoglobulin/anti-immunoglobulin reaction was demonstrated working with subacute sclerosing panencephalitis (SSPE) and control serum IgG. This protein was isolated from SSPE and normal human blood, it