Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Paul Stickings"'
Autor:
Marcel H.N. Hoefnagel, Paul Stickings, Dean Smith, Carmen Jungbäck, Wim Van Molle, Lorenzo Tesolin
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 369-377 (2023)
Introduction There are rational arguments to replace existing in vivo potency and safety assays for batch release testing of vaccines with more advanced non-animal techniques to measure critical quality attributes. However, the introduction of in vit
Externí odkaz:
https://doaj.org/article/4509f536acc5435da3513fc7a0fa1c3f
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-4 (2021)
Abstract The past 18 months have seen an unprecedented approach to vaccine development in the global effort against the COVID-19 pandemic. The process from discovery research, through clinical trials and regulatory approval often takes more than 10 y
Externí odkaz:
https://doaj.org/article/b34105000438424991c08c1643101094
Publikováno v:
Vaccine: X, Vol 8, Iss , Pp 100099- (2021)
Tetanus antitoxin, produced in animals, has been used for the prevention and treatment of tetanus for more than 100 years. The availability of antitoxins, ethical issues around production, and risks involved in the use of animal derived serum product
Externí odkaz:
https://doaj.org/article/4658864054444ee3a278aa1b75fa0e43
Autor:
Kiran P. Malik, Chinwe Duru, Paul Stickings, Esther Veronika Wenzel, Michael Hust, Paul Matejtschuk
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1948 (2021)
When preparing biological reference materials, the stability of the lyophilized product is critical for long-term storage, particularly in order to meet WHO International Standards, which are not assigned expiry dates but are expected to be in use fo
Externí odkaz:
https://doaj.org/article/f03c573bd3cd495e9e73c21d6a9d97db
Autor:
Arnold Duralliu, Paul Matejtschuk, Paul Stickings, Laura Hassall, Robert Tierney, Daryl R. Williams
Publikováno v:
Pharmaceutics, Vol 12, Iss 4, p 303 (2020)
High protein concentration products for targeted therapeutic use are often freeze-dried to enhance stability. The long-term storage stability of freeze-dried (FD) plasma-derived Immunoglobulin G (IgG) from moderate to high concentrations (10–200 mg
Externí odkaz:
https://doaj.org/article/48fe2922b30a43588fe541432876f45d
Autor:
Aleksander Rust, Ciara Doran, Rosalyn Hart, Thomas Binz, Paul Stickings, Dorothea Sesardic, Andrew A. Peden, Bazbek Davletov
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Botulinum neurotoxins (BoNTs) type A and type B are commonly used as biopharmaceutics for neurological diseases, uniquely allowing months-long paralysis of target muscles. Their exquisite neuronal specificity is conferred by a multistep process of bi
Externí odkaz:
https://doaj.org/article/a5d1ff3943c640b299a8d604ee755862
Publikováno v:
Toxins, Vol 9, Iss 7, p 230 (2017)
Botulinum toxins (BoNTs), of which there are seven serotypes, are among the most potent neurotoxins, with serotypes A, B and E causing human botulism. Antitoxins form the first line of treatment for botulism, and functional, highly sensitive in vitro
Externí odkaz:
https://doaj.org/article/5641e63ee04547e69a11c9084c302af6
Autor:
Maxime Vermeulen, Isabelle Feck, Antoine Francotte, Laura Hassall, Lorenzo Tesolin, Wim Van Molle, Romain Pizzato, Thierry Laurent, Charline Hoebreck, Paul Stickings, Alexandre Dobly
Publikováno v:
Journal of Immunological Methods. 517:113483
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35d4df47b6387fa87d44f47f1627b3ae
https://doi.org/10.1016/j.jim.2023.113483
https://doi.org/10.1016/j.jim.2023.113483
Autor:
Elliot Lilley, Emmanuelle Coppens, Pradip Das, Francis Galaway, Richard Isbrucker, Sarah Sheridan, Paul Stickings, Anthony Holmes
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization.
The UK National Centre for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs) has been tasked by the World Health Organization (WHO) to review the extent to which animal-based testing methods are described in their manuals, gui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b3eb4ea5b71dce56bb19dc940e0458
https://pubmed.ncbi.nlm.nih.gov/36376163
https://pubmed.ncbi.nlm.nih.gov/36376163
Publikováno v:
Biologicals. 82:101682
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4d51a9fcb3ea381061ca7a78784fbad
https://doi.org/10.1016/j.biologicals.2023.101682
https://doi.org/10.1016/j.biologicals.2023.101682