Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Paul Shami"'
Autor:
Justin Watts, Tara L. Lin, Alice Mims, Prapti Patel, Cynthia Lee, Anoush Shahidzadeh, Paul Shami, Elizabeth Cull, Christopher R. Cogle, Eunice Wang, Fatih M. Uckun
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
APVO436 is a recombinant bispecific antibody designed to direct host cytotoxic T-cells to CD123-expressing blast cells in patients with hematologic malignancies. APVO436 showed promising tolerability and single-agent activity in relapsed or refractor
Externí odkaz:
https://doaj.org/article/428b3dd5b7034e30953581d8a30b3ea9
Autor:
Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice Wang, Jayastu Senapati, Nathaniel R. Wilson, Marina Konopleva, Arthur E. Frankel, Vikas Gupta, Ruben Mesa, Matthew Ulrickson, Edward Gorak, Sumeet Bhatia, Tulin Budak-Alpdogan, James Mason, Maria Teresa Garcia-Romero, Norma Lopez-Santiago, Gabriela Cesarman-Maus, Pankit Vachhani, Sangmin Lee, Vijaya Raj Bhatt, William Blum, Roland B. Walter, Dale Bixby, Ivana Gojo, Madeleine Duvic, Raajit K. Rampal, Marcos de Lima, James Foran, Amir T. Fathi, Aric Cameron Hall, Meagan A. Jacoby, Jeffrey Lancet, Gabriel Mannis, Anthony S. Stein, Alice Mims, David Rizzieri, Rebecca Olin, Alexander Perl, Gary Schiller, Paul Shami, Richard M. Stone, Stephen Strickland, Matthew J. Wieduwilt, Naval Daver, Farhad Ravandi, Sumithira Vasu, Monica Guzman, Gail J. Roboz, Joseph Khoury, Muzaffar Qazilbash, Phyu P. Aung, Branko Cuglievan, Yazan Madanat, Mohamed A. Kharfan-Dabaja, Anna Pawlowska, Justin Taylor, Martin Tallman, Prajwal Dhakal, Andrew A. Lane
Publikováno v:
Blood. 141:567-578
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with historically poor outcomes and no worldwide consensus treatment approach. Unique among most hematologic malignancies for its frequent cutaneous involvement, BP
Publikováno v:
Journal of Controlled Release. 349:425-433
PD-1 immune checkpoint has been intensively investigated in pathogenesis and treatments for cancer and autoimmune diseases. Cells that express PD-1 (PD-1
Autor:
M. Tommy Gambles, Jiahui Li, D. Christopher Radford, Douglas Sborov, Paul Shami, Jiyuan Yang, Jindřich Kopeček
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 350
Drug-Free Macromolecular Therapeutics (DFMT) is a new paradigm in macromolecular therapeutics that induces apoptosis in target cells by crosslinking receptors without the need of low molecular weight drugs. Programmed cell death is initiated via a bi
Autor:
Susan, O'Brien, Ellin, Berman, Kapil, Bhalla, Edward A, Copelan, Marcel P, Devetten, Peter D, Emanuel, Harry P, Erba, Peter L, Greenberg, Joseph O, Moore, Donna, Przepiorka, Jerald P, Radich, Russell J, Schilder, Paul, Shami, B Douglas, Smith, David S, Snyder, Robert J, Soiffer, Martin S, Tallman, Moshe, Talpaz, Meir, Wetzler
Publikováno v:
Journal of the National Comprehensive Cancer Network : JNCCN. 3(6)
Autor:
Paul Shami, Larry K. Keefer, Michael L. Citro, Lai Yi Wang, Melissa N. Booth, Joseph E. Saavedra, Keith M. Davies
Publikováno v:
Journal of medicinal chemistry. 43(2)
We have designed a novel prodrug class that is stable in neutral aqueous media but releases bioactive nitric oxide (NO) on metabolism by esterase. Diazeniumdiolates of structure R(2)N-N(O)=N-OR', in which R' = Na, were reacted with BrCH(2)OAc to conv
Autor:
Margaret R, O'Donnell, Frederick R, Appelbaum, Maria R, Baer, John C, Byrd, Steven E, Coutre, Lloyd E, Damon, Harry P, Erba, Eli, Estey, James, Foran, Jeffrey, Lancet, Lori J, Maness, Peter G, Maslak, Michael, Millenson, Joseph O, Moore, Donna, Przepiorka, Paul, Shami, B Douglas, Smith, Richard M, Stone, Martin S, Tallman
Publikováno v:
Journal of the National Comprehensive Cancer Network. 4:16
Approximately 11,960 people will be diagnosed with acute myeloid leukemia (AML) in 2005, and 9,000 patients will die of the disease. As the population ages, the incidence of AML, along with myelodysplasia, appears to be rising. Equally disturbing is