Predicting substitutions to modulate disorder and stability in coiled-coils

Autor: Yasaman Karami, Paul Saighi, Rémy Vanderhaegen, Denis Gerlier, Sonia Longhi, Elodie Laine, Alessandra Carbone

Publikováno v: BMC Bioinformatics, Vol 21, Iss S19, Pp 1-20 (2020)

Abstract Background Coiled-coils are described as stable structural motifs, where two or more helices wind around each other. However, coiled-coils are associated with local mobility and intrinsic disorder. Intrinsically disordered regions in protein

Externí odkaz: https://doaj.org/article/c4b97fa0ca044aaea8f46b21eb323d2d

Predicting substitutions to modulate disorder and stability in coiled-coils

Autor: Paul Saighi, Sonia Longhi, Denis Gerlier, Elodie Laine, Alessandra Carbone, Yasaman Karami, Remy Vanderhaegen

Publikováno v: BMC Bioinformatics
BMC Bioinformatics, BioMed Central, 2020, 21 (S19), ⟨10.1186/s12859-020-03867-x⟩
BMC Bioinformatics, 2020, 21 (S19), ⟨10.1186/s12859-020-03867-x⟩
BMC Bioinformatics, 2020, 21 (S19), pp.573. ⟨10.1186/s12859-020-03867-x⟩
BMC Bioinformatics, Vol 21, Iss S19, Pp 1-20 (2020)

Coiled-coils are described as stable structural motifs, where two or more helices wind around each other. However, coiled-coils are associated with local mobility and intrinsic disorder. Intrinsically disordered regions (IDRs) in proteins are charact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373d02c948f3997f100a0ac4aafbe816
https://hal.archives-ouvertes.fr/hal-03154196

Predicting substitutions to modulate disorder and stability in coiled-coils.

Autor: Karami, Yasaman^1,2 (AUTHOR) yasaman.karami@pasteur.fr, Saighi, Paul¹ (AUTHOR), Vanderhaegen, Rémy¹ (AUTHOR), Gerlier, Denis³ (AUTHOR), Longhi, Sonia⁴ (AUTHOR), Laine, Elodie¹ (AUTHOR) elodie.laine@upmc.fr, Carbone, Alessandra^1,5 (AUTHOR) alessandra.carbone@lip6.fr

Publikováno v: BMC Bioinformatics. 12/21/2020 Supplement 19, Vol. 21 Issue 19, p1-20. 20p.