Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Paul S. Uster"'
Publikováno v:
International Journal of Pharmaceutics. 162:77-86
The activity of doxorubicin hydrochloride in preclinical tumor models is markedly improved by encapsulation in pegylated liposomes (DOXIL, CAELYX). To understand this response in better detail, spatial and temporal drug distribution in frozen tumor s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9cde7f3646408409ed293229ddb1cdb
https://doi.org/10.1016/s0378-5173(97)00415-8
https://doi.org/10.1016/s0378-5173(97)00415-8
Autor:
Zhu George Z, Mary S. Newman, Theresa M. Allen, Cecilia J. Mendez, Paul S. Uster, Barbra E. Daniel
Publikováno v:
FEBS Letters. 386:243-246
Transfer of MPEG1900-DSPE from micellar phase to pre-formed liposomes imparts long in vivo circulation half-life to an otherwise rapidly cleared lipid composition. MPEG1900-DSPE transfers efficiently and quickly in a time and temperature dependent ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf7b89286776af7c5ed937d590d7ab4
https://doi.org/10.1016/0014-5793(96)00452-8
https://doi.org/10.1016/0014-5793(96)00452-8
Publikováno v:
International Journal of Cancer. 62:199-204
Vincristine is used clinically for the treatment of various types of cancer. Recent significant therapeutic improvements obtained by entrapping anthracyclines in sterically stabilized liposomes raised the question whether the therapeutic index of vin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6a92197c79ead9c122649966d1e26a
https://doi.org/10.1002/ijc.2910620215
https://doi.org/10.1002/ijc.2910620215
Publikováno v:
International journal of pharmaceutics. 365(1-2)
The objective of this study was to evaluate the safety and pharmacokinetics of unit dose budesonide (UDB), an aqueous dispersion of submicron-sized budesonide particles, and a commercially available budesonide suspension formulation. This was a rando
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7884cb39a16050b0550a164d74c3667
https://pubmed.ncbi.nlm.nih.gov/18786624
https://pubmed.ncbi.nlm.nih.gov/18786624
Publikováno v:
Long Circulating Liposomes: Old Drugs, New Therapeutics ISBN: 9783662221174
Studies in animal tumor models have found that the therapeutic effects of antican-cer drugs can be enhanced and prolonged, and their toxic side effects reduced, when the drugs are encapsulated in liposomes.1,2 The effectiveness of drugs in convention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10235de1eeed048c16d2e33868ee80b6
https://doi.org/10.1007/978-3-662-22115-0_5
https://doi.org/10.1007/978-3-662-22115-0_5
Autor:
Edwin Oto, Yolanda P. Quinn, Charles Engbers, Mary S. Newman, Zhu George Z, Paul S. Uster, Jan Vaage
Publikováno v:
Cancer chemotherapy and pharmacology. 39(1-2)
Poly(ethylene glycol) (PEG)-derivatized liposome vehicles improve antitumor effectiveness of entrapped anthracyclines and vinca alkaloids. However, the plasma clearance of entrapped vincristine is substantially faster than the lipid phase or other en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f395d50edd2d7b636bc2fd73c90da1
https://pubmed.ncbi.nlm.nih.gov/8995511
https://pubmed.ncbi.nlm.nih.gov/8995511
Publikováno v:
International journal of cancer. 54(6)
This study tested the therapeutic effects of vincristine sulfate and doxorubicin hydrochloride, each drug in 2 different formulations: (i) as a solution in saline, and (ii) encapsulated in sterically stabilized, long-circulating liposomes composed of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87971551302c1c89ffcb68160dd18bdd
https://pubmed.ncbi.nlm.nih.gov/8335404
https://pubmed.ncbi.nlm.nih.gov/8335404
Autor:
Paul S. Uster
Publisher Summary The resolution limit of fluorescence light microscopy (about 400 nm) can be exceeded indirectly by using resonance energy transfer (RET) microscopy. This technique is able to visualize the spatial location of two different, fluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5e077f4b5bf1e3ddebb6a4ece91c99d
https://doi.org/10.1016/0076-6879(93)21021-y
https://doi.org/10.1016/0076-6879(93)21021-y
Autor:
David W. Deamer, Paul S. Uster
Publikováno v:
Archives of Biochemistry and Biophysics. 209:385-395
A sensitive, quantitative assay has been developed which measures the extent of liposome fusion by monitoring fluorescence resonance energy transfer between two lipid analogs originally in separate membranes. This transfer of photon energy from donor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df571aa85289d863e886bf62a477a341
https://doi.org/10.1016/0003-9861(81)90296-4
https://doi.org/10.1016/0003-9861(81)90296-4
Publikováno v:
Cryobiology. 23:245-255
The relative abilities of a number of naturally occurring carbohydrates to inhibit dehydration-induced fusion between palmitoyloleoylphosphatidylcholine:phosphatidylserine (85:15) large unilamellar vesicles have been studied. Fusion events were quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbfac999252312e803e35d41ab9faf9
https://doi.org/10.1016/0011-2240(86)90050-7
https://doi.org/10.1016/0011-2240(86)90050-7