Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paul S. Swerdlow"'
Publikováno v:
Blood. 92:2924-2933
XTENSIVE INVESTIGATION has demonstrated that the clinical severity of the b-globin disorders can be ameliorated by increased expression of the fetal globin genes. 1,2 Several pharmacologic agents stimulate fetal globin production in patients with b-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee2daaffb0013eb944548ae82f9e000c
https://doi.org/10.1182/blood.v92.8.2924
https://doi.org/10.1182/blood.v92.8.2924
Publikováno v:
Blood. 92:2924-2933
The mechanisms by which pharmacologic agents stimulate γ-globin gene expression in β-globin disorders has not been fully established at the molecular level. In studies described here, nucleated erythroblasts were isolated from patients with β-glob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a7c69ebe03f6ccff26fbd617adafe2f
https://doi.org/10.1182/blood.v92.8.2924.420k16_2924_2933
https://doi.org/10.1182/blood.v92.8.2924.420k16_2924_2933
Autor:
Wally R, Smith, Samir K, Ballas, William F, McCarthy, Robert L, Bauserman, Paul S, Swerdlow, Martin H, Steinberg, Myron A, Waclawiw, M, Waclawiw
Background. We compared daily pain, home analgesic use, and utilization among ambulatory adults in the randomized Multicenter Study of Hydroxyurea in Sickle Cell Anemia (MSH). We related the fetal hemoglobin (HbF) hydroxyurea response to these respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206482040b0a288e5e70a23aa9a2abea
https://europepmc.org/articles/PMC6818651/
https://europepmc.org/articles/PMC6818651/
Autor:
Robyn J, Barst, Kamal K, Mubarak, Roberto F, Machado, Kenneth I, Ataga, Raymond L, Benza, Oswaldo, Castro, Robert, Naeije, Namita, Sood, Paul S, Swerdlow, Mariana, Hildesheim, Mark T, Gladwin, M, Telen
Publikováno v:
British journal of haematology. 149(3)
Doppler-defined pulmonary hypertension (PH) in sickle cell disease (SCD) is associated with 40% mortality at 40 months. To assess the effect of bosentan in SCD-PH, two randomized, double-blind, placebo-controlled, 16-week studies were initiated. Safe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ecdd1ed2e6592d3fbac443483dd64c
https://pubmed.ncbi.nlm.nih.gov/20175775
https://pubmed.ncbi.nlm.nih.gov/20175775
Autor:
Wally R, Smith, Robert L, Bauserman, Samir K, Ballas, William F, McCarthy, Martin H, Steinberg, Paul S, Swerdlow, Myron A, Waclawiw, Bruce A, Barton, M, Waclawiw
Publikováno v:
Pain. 146(1-2)
No multi-site comparisons have tested whether seasonally cold temperature or climate exacerbate pain intensity in sickle cell disease (SCD). We examined seasonal SCD pain intensity and frequency patterns and compared them with concurrent climate cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589a078d7fbc1494b6b269ce4610ba74
https://pubmed.ncbi.nlm.nih.gov/19683393
https://pubmed.ncbi.nlm.nih.gov/19683393
Publikováno v:
Molecular and cellular biology. 10(9)
Histones H2A and H2B are modified by ubiquitination of specific lysine residues in higher and lower eucaryotes. To identify functions of ubiquitinated histone H2A, we studied an organism in which genetic analysis of histones is feasible, the yeast Sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9c826b2bc2d10ff92ec290c9894b28
https://pubmed.ncbi.nlm.nih.gov/2201907
https://pubmed.ncbi.nlm.nih.gov/2201907
Autor:
Paul S. Swerdlow
Publikováno v:
JAMA: The Journal of the American Medical Association. 267:2738
In Reply. —Dr Crosby lucidly illustrates the misuse of iron in the treatment of anemia unrelated to iron deficiency. Patients also misuse over-the-counter iron preparations. Self-treatment can result in significant iron overload or delayed diagnose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8622a7d4815df22f9faa12d2a698b6b
https://doi.org/10.1001/jama.1992.03480200046014
https://doi.org/10.1001/jama.1992.03480200046014
Autor:
Paul S. Swerdlow
Publikováno v:
JAMA: The Journal of the American Medical Association. 267:560
The therapeutic use of iron in medicine goes back nearly as far as recorded medicine itself. In 1500 BC, the Egyptians used iron therapeutically. 1 The ancient Hindu medicine Lauha Bhasma is essentially an iron preparation. 2 Cycles of iron use in ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54af5642f4e51a67b548934185563950
https://doi.org/10.1001/jama.1992.03480040108041
https://doi.org/10.1001/jama.1992.03480040108041
Publikováno v:
Blood. 71:1153-1156
Murine erythroleukemia cells are useful for studying the regulation of erythroid differentiation since these malignant pronormoblasts differentiate to orthochromatic normoblasts when treated with a variety of inducing agents. Changes in chromatin pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d023ca4ff00c010a1679b252ff305e6d
https://doi.org/10.1182/blood.v71.4.1153.1153
https://doi.org/10.1182/blood.v71.4.1153.1153
Autor:
Paul S. Swerdlow, Alexander Varshavsky
Publikováno v:
Nucleic acids research. 11(2)
We have used a two-dimensional (deoxyribonucleoprotein leads to DNA) electrophoretic binding assay to study the interaction of the purified high mobility group protein HMG17 with isolated HeLa mononucleosomes as a function of their DNA fragment size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccb39efa8204c38f0bf77cd0319e07f
https://pubmed.ncbi.nlm.nih.gov/6298725
https://pubmed.ncbi.nlm.nih.gov/6298725