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pro vyhledávání: '"Paul S. Miller"'
Autor:
Paul S. Miller
Publikováno v:
Recombinant DNA Principles and Methodologies ISBN: 9781003067658
Recombinant DNA Principles and Methodologies
Recombinant DNA Principles and Methodologies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cb20e2d2540661b0994eae781bced75
https://doi.org/10.1201/9781003067658-2
https://doi.org/10.1201/9781003067658-2
Autor:
Vikram Babu Kasaragod, Martin Mortensen, Steven W. Hardwick, Ayla A. Wahid, Valentina Dorovykh, Dimitri Y. Chirgadze, Trevor G. Smart, Paul S. Miller
Publikováno v:
Nature. 604:E15-E15
Autor:
A. Radu Aricescu, Els Pardon, Jan Steyaert, Luigi De Colibus, Suzanne Scott, Paul S. Miller, S. Masiulis
Publikováno v:
Nature Structural & Molecular Biology. 24:986-992
Type-A γ-aminobutyric acid receptors (GABAARs) are the principal mediators of inhibitory neurotransmission in the human brain. Endogenous neurosteroids interact with GABAARs to regulate acute and chronic anxiety and are potent sedative, analgesic, a
Autor:
Mark S.P. Sansom, Trevor G. Smart, Zhaoyang Sun, Els Pardon, Gianni Klesse, Sreenivas Chavali, Saad Hannan, J.M. Diprose, S. Masiulis, Luigi De Colibus, Abhay Kotecha, Shanlin Rao, Paul S. Miller, Brandon Frenz, Juha T. Huiskonen, Stephen J. Tucker, Frank DiMaio, Suzanne Scott, Tomas Malinauskas, Alistair Siebert, Robert Esnouf, Radu Aricescu, Sai Li, Jan Steyaert, M. Madan Babu
Type-A γ-aminobutyric acid (GABAA) receptors are pentameric ligand-gated ion channels (pLGICs), typically consisting of α/β/γ subunit combinations. They are the principal mediators of inhibitory neurotransmission throughout the central nervous sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d5673ebc6cb19d77170ae851e68ebf
https://doi.org/10.1101/338343
https://doi.org/10.1101/338343
Autor:
Janice Perry Evans, Paul S. Miller
Publikováno v:
Biology of reproduction. 99(5)
Publikováno v:
Biochemistry. 54:2270-2282
Platinum-derivatized homopyrimidine triplex-forming oligonucleotides (Pt-TFOs) consisting of 2'-O-methyl-5-methyluridine, 2'-O-methyl-5-methylcytidine, and a single 3'-N7-trans-chlorodiammine platinum(II)-2'-deoxyguanosine were designed to cross-link
Autor:
Mindy K. Graham, Paul S. Miller
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 17:1197-1208
Platinated triplex-forming oligonucleotides (TFOs) consisting of 2'-methoxythymidine and 2'-methoxy-5-methylcytidine and an N-7 platinated deoxyguanosine ((Pt)G) at the 5'-((Pt)G-TFO), 3'-(TFO-G(Pt)), or 3'- and 5'-((Pt)G-TFO-G(Pt)) ends of the TFO f
Autor:
Denis V. Titov, Benjamin Gilman, Shridhar Bhat, Yongjun Dang, James A. Goodrich, Jun O. Liu, Paul S. Miller, Jennifer F. Kugel, Woon-Kai Low, Qing-Li He, Arnold L. Demain, Michael B. Smeaton
Publikováno v:
Nature Chemical Biology. 7:182-188
Triptolide (1) is a structurally unique diterpene triepoxide isolated from a traditional Chinese medicinal plant with anti-inflammatory, immunosuppressive, contraceptive and antitumor activities. Its molecular mechanism of action, however, has remain
Autor:
Anthony D. Saleh, Paul S. Miller
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 30:235-255
In order to enhance the efficacy of small antisense molecules, we examined a series of antisense oligonucleotides derivatized with functional groups designed to enable them to hydrolyze their RNA target. Solid phase synthetic methods were used to pre
Autor:
Mary Castillo, Adam B. Fisher, Paul S. Miller, Starsha Kolodziej, Ning Li, Jose M. Lora, Daniel S. Leventhal, Carey W. Gallant, Anna Sokolovska, Chris Plescia, Kip A. West
Publikováno v:
Cancer Research. 78:LB-131
Background: While both T-cell priming and blockade of immune suppression play critical roles in the generation of an efficacious antitumor immune response, most therapies fail to support both processes as a single agent. At Synlogic we are using synt