Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Paul S. Jones"'
Autor:
Gareth C. G. Davies, Neesha Dedi, Paul S. Jones, Lara Kevorkian, David McMillan, Cristina Ottone, Monika-Sarah E. D. Schulze, Anthony Scott-Tucker, Roohi Tewari, Shauna West, Michael Wright, Tania F. Rowley
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTGremlin-1, a high-affinity antagonist of bone morphogenetic proteins (BMP)-2, −4, and −7, is implicated in tumor initiation and progression. Increased gremlin-1 expression, and therefore suppressed BMP signaling, correlates with poor prog
Externí odkaz:
https://doaj.org/article/b953f7c54c694fe2b318ac8406c9743d
Autor:
Heather J. Bax, Jitesh Chauhan, Chara Stavraka, Atousa Khiabany, Mano Nakamura, Giulia Pellizzari, Kristina M. Ilieva, Sara Lombardi, Hannah J. Gould, Christopher J. Corrigan, Stephen J. Till, Sidath Katugampola, Paul S. Jones, Claire Barton, Anna Winship, Sharmistha Ghosh, Ana Montes, Debra H. Josephs, James F. Spicer, Sophia N. Karagiannis
Publikováno v:
Cells, Vol 9, Iss 7, p 1631 (2020)
Basophils are involved in manifestations of hypersensitivity, however, the current understanding of their propensity for activation and their prognostic value in cancer patients remains unclear. As in healthy and atopic individuals, basophil populati
Externí odkaz:
https://doaj.org/article/caee5e2d6a73467a978d97ba24be3e41
Autor:
Michelle D. Garrett, Neil T. Thompson, Paul Workman, Suzanne A. Eccles, Florence I. Raynaud, John F. Lyons, Thomas G. Davies, Steven J. Woodhead, Matthias Reule, Ruth E. Feltell, Paul S. Jones, Kathrin Heinzmann, Simon P. Heaton, Anna Zetterlund, Vanessa Martins, Alexis K. de Haven Brandon, Melanie R. Valenti, Paul D. Eve, Robert H. te Poele, Kyla M. Grimshaw, Mike I. Walton, Timothy A. Yap
PDF file - 81K, Supplementary data comprising the materials and methods for (i) crystallography (ii) gene expression studies (iii) siRNA studies and Supplementary Figure legends 1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136ef480c6dff64c10335140171ee9da
https://doi.org/10.1158/1078-0432.22446023.v1
https://doi.org/10.1158/1078-0432.22446023.v1
Autor:
Sophia N. Karagiannis, James F. Spicer, Philip J. Blower, Victoria Sanz-Moreno, Hannah J. Gould, Paul S. Jones, Frank O. Nestle, Andrew J. Beavil, Christopher J. Corrigan, David Dombrowicz, Noel Downes, Ana Montes, Mariangela Figini, Silvana Canevari, Sophia Tsoka, Gareth Muirhead, Elliott Lever, Claire Barton, Heike Lentfer, Christopher Selkirk, Marguerite Bracher, Alexander Koers, Amy E. Gilbert, Giulia Chiaruttini, Silvia Mele, Natalie Woodman, Patrycja Gazinska, Silvia Crescioli, Matthew Fittall, Isabel Correa, Kristina M. Ilieva, Cecilia Herraiz, Anthony Cheung, Panagiotis Karagiannis, Louise Saul, Giulia Pellizzari, Mano Nakamura, Mirella Georgouli, Tihomir Dodev, Heather J. Bax, Debra H. Josephs
Evaluation of FRalpha expression by tumor cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38db7cb9edccc92a72b16204c6c84d78
https://doi.org/10.1158/0008-5472.22416014.v1
https://doi.org/10.1158/0008-5472.22416014.v1
Autor:
Sophia N. Karagiannis, James F. Spicer, Philip J. Blower, Victoria Sanz-Moreno, Hannah J. Gould, Paul S. Jones, Frank O. Nestle, Andrew J. Beavil, Christopher J. Corrigan, David Dombrowicz, Noel Downes, Ana Montes, Mariangela Figini, Silvana Canevari, Sophia Tsoka, Gareth Muirhead, Elliott Lever, Claire Barton, Heike Lentfer, Christopher Selkirk, Marguerite Bracher, Alexander Koers, Amy E. Gilbert, Giulia Chiaruttini, Silvia Mele, Natalie Woodman, Patrycja Gazinska, Silvia Crescioli, Matthew Fittall, Isabel Correa, Kristina M. Ilieva, Cecilia Herraiz, Anthony Cheung, Panagiotis Karagiannis, Louise Saul, Giulia Pellizzari, Mano Nakamura, Mirella Georgouli, Tihomir Dodev, Heather J. Bax, Debra H. Josephs
Table of Patient Characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae24e70842a424500fbe06f48794886
https://doi.org/10.1158/0008-5472.22416008.v1
https://doi.org/10.1158/0008-5472.22416008.v1
Autor:
Sophia N. Karagiannis, James F. Spicer, Philip J. Blower, Victoria Sanz-Moreno, Hannah J. Gould, Paul S. Jones, Frank O. Nestle, Andrew J. Beavil, Christopher J. Corrigan, David Dombrowicz, Noel Downes, Ana Montes, Mariangela Figini, Silvana Canevari, Sophia Tsoka, Gareth Muirhead, Elliott Lever, Claire Barton, Heike Lentfer, Christopher Selkirk, Marguerite Bracher, Alexander Koers, Amy E. Gilbert, Giulia Chiaruttini, Silvia Mele, Natalie Woodman, Patrycja Gazinska, Silvia Crescioli, Matthew Fittall, Isabel Correa, Kristina M. Ilieva, Cecilia Herraiz, Anthony Cheung, Panagiotis Karagiannis, Louise Saul, Giulia Pellizzari, Mano Nakamura, Mirella Georgouli, Tihomir Dodev, Heather J. Bax, Debra H. Josephs
IgE antibodies are key mediators of antiparasitic immune responses, but their potential for cancer treatment via antibody-dependent cell-mediated cytotoxicity (ADCC) has been little studied. Recently, tumor antigen–specific IgEs were reported to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816bd38045ed7ffde480f7e6dc0d11ea
https://doi.org/10.1158/0008-5472.c.6509447.v1
https://doi.org/10.1158/0008-5472.c.6509447.v1
Autor:
Michelle D. Garrett, Neil T. Thompson, Paul Workman, Suzanne A. Eccles, Florence I. Raynaud, John F. Lyons, Thomas G. Davies, Steven J. Woodhead, Matthias Reule, Ruth E. Feltell, Paul S. Jones, Kathrin Heinzmann, Simon P. Heaton, Anna Zetterlund, Vanessa Martins, Alexis K. de Haven Brandon, Melanie R. Valenti, Paul D. Eve, Robert H. te Poele, Kyla M. Grimshaw, Mike I. Walton, Timothy A. Yap
XLS file - 703K, Gene expression data for CCT128930: Genes that showed at least a 1.5 Fold Change in at least one treated sample compared to vehicle control and were differentially expressed between the treatment groups (Welch ANOVA FDR5%)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264e5ae7347bb9dfece9541b75115729
https://doi.org/10.1158/1078-0432.22446017.v1
https://doi.org/10.1158/1078-0432.22446017.v1
Autor:
Sophia N. Karagiannis, James F. Spicer, Philip J. Blower, Victoria Sanz-Moreno, Hannah J. Gould, Paul S. Jones, Frank O. Nestle, Andrew J. Beavil, Christopher J. Corrigan, David Dombrowicz, Noel Downes, Ana Montes, Mariangela Figini, Silvana Canevari, Sophia Tsoka, Gareth Muirhead, Elliott Lever, Claire Barton, Heike Lentfer, Christopher Selkirk, Marguerite Bracher, Alexander Koers, Amy E. Gilbert, Giulia Chiaruttini, Silvia Mele, Natalie Woodman, Patrycja Gazinska, Silvia Crescioli, Matthew Fittall, Isabel Correa, Kristina M. Ilieva, Cecilia Herraiz, Anthony Cheung, Panagiotis Karagiannis, Louise Saul, Giulia Pellizzari, Mano Nakamura, Mirella Georgouli, Tihomir Dodev, Heather J. Bax, Debra H. Josephs
Description of additional experiments and procedures carried out in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e224e5f523a06cb1b657edf1f2f3944
https://doi.org/10.1158/0008-5472.22416011.v1
https://doi.org/10.1158/0008-5472.22416011.v1
Autor:
Michelle D. Garrett, Neil T. Thompson, Paul Workman, Suzanne A. Eccles, Florence I. Raynaud, John F. Lyons, Thomas G. Davies, Steven J. Woodhead, Matthias Reule, Ruth E. Feltell, Paul S. Jones, Kathrin Heinzmann, Simon P. Heaton, Anna Zetterlund, Vanessa Martins, Alexis K. de Haven Brandon, Melanie R. Valenti, Paul D. Eve, Robert H. te Poele, Kyla M. Grimshaw, Mike I. Walton, Timothy A. Yap
Purpose: Deregulated phosphatidylinositol 3-kinase pathway signaling through AGC kinases including AKT, p70S6 kinase, PKA, SGK and Rho kinase is a key driver of multiple cancers. The simultaneous inhibition of multiple AGC kinases may increase antitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dad559501b49bb682286db9d7d443d
https://doi.org/10.1158/1078-0432.c.6520622
https://doi.org/10.1158/1078-0432.c.6520622
Autor:
Michelle D. Garrett, Neil T. Thompson, Paul Workman, Suzanne A. Eccles, Florence I. Raynaud, John F. Lyons, Thomas G. Davies, Steven J. Woodhead, Matthias Reule, Ruth E. Feltell, Paul S. Jones, Kathrin Heinzmann, Simon P. Heaton, Anna Zetterlund, Vanessa Martins, Alexis K. de Haven Brandon, Melanie R. Valenti, Paul D. Eve, Robert H. te Poele, Kyla M. Grimshaw, Mike I. Walton, Timothy A. Yap
XLS file - 66K, Genes that showed at least a 1.5 Fold Change in at least one treated sample compared to vehicle control and were differentially expressed between the treatment groups (Welch ANOVA FDR5%) for both CCT128930 and AT13148
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02505457843f17ab3c7bd679c87ef577
https://doi.org/10.1158/1078-0432.22446008
https://doi.org/10.1158/1078-0432.22446008