Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Paul S. Guth"'
Publikováno v:
Annals of the New York Academy of Sciences. 104:53-68
Autor:
Ulrich Förstermann, Ulf-Rüdiger Heinrich, Jan Maurer, Paul S. Guth, Wolf J. Mann, Maria Lioudyno
Publikováno v:
Journal of Electron Microscopy. 52:197-206
There is growing evidence for a nitric oxide/cyclic GMP pathway of signal transduction in the vestibular system. Recently, two isoforms of nitric oxide (NO) synthase (nNOS and eNOS) and NO itself have been identified at the light microscopic level in
Autor:
Paul S. Guth, Ana F. Silbering, Marı́a E. Gomez Casati, Carla V. Rothlin, Maria Lioudyno, A. Belén Elgoyhen, Paola V. Plazas, Eleonora Katz
Publikováno v:
Molecular Pharmacology. 63:1067-1074
In the present work, we characterized the effects of serotonin type 3 receptor ligands on recombinant and native α9α10-containing nicotinic acetylcholine receptors (nAChRs). Our results indicate that the recombinant α9α10 nAChR shares striking ph
Autor:
Paul S. Guth, Adam W. Hendricson
Publikováno v:
Hearing Research. 172:99-109
The response of the semicircular canal (SCC) to the group I mGluR-selective agonist dihydroxyphenylglycine (DHPG; 300 microM) - facilitation of afferent discharge rate - was dose-dependently reduced by the phospholipase C inhibitor U-73122 (1-100 mic
Publikováno v:
Hearing Research. 149:167-177
Nicotinic acetylcholine (nACh) receptors are known to be targets for modulation by a number of substances, including the opiates. It is known that acetylcholine (ACh) coexists with opioid peptides in cochlear efferent neurons, and such a colocalizati
Publikováno v:
Hearing Research. 146:17-27
Acetylcholine (ACh) is the dominant transmitter released from inner ear efferent neurons. In frog vestibular organs, these efferent neurons synapse exclusively with type II hair cells. Hair cells isolated from the frog saccule hyperpolarize following
Autor:
Laura Botta, Paul S. Guth, Grace B. Athas, Meredith M. Garcia, G. Zucca, Amrita Puri, Joseph C. Holt, Paola Perin, Paolo Valli
Publikováno v:
Hearing Research. 125:154-162
This research sought to test the presence and function of metabotropic excitatory amino acid receptors (mGluR) in the frog semicircular canal (SCC). The mGluR agonist ˛ 1-aminocyclopentane-trans-1,3-dicarboxylate (ACPD) produced an increase in affer
Publikováno v:
Primary Sensory Neuron. 2:275-282
Previous data from this group indicated that the main cholinergic effect on the afferent resting firing rate of the posterior canal is an atropine-sensitive, strychnine-resistant facilitation, while the main effect on the saccule is a strychnine-sens
Publikováno v:
Neuroscience. 64:1153-1160
Previous studies have shown that low concentrations of exogenous ATP, added to the perilymphatic fluid, could modify the bioelectrical activity of the isolated semicircular canal of the frog (Rana pipiens). To test the hypothesis that ATP is endogeno
Publikováno v:
Hearing Research. 73:109-115
The list of distinguishing morphological features of hair cells includes: Type I and Type II afferent innervation, and length, shapes and arrangements of stereo- and kinocilia. We now add to this list the shapes of the hair cells themselves and their