Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Paul S. Burgoyne"'
Autor:
Aminata Touré, Emily J. Clemente, Peter J. I. Ellis, Shantha K. Mahadevaiah, Obah A. Ojarikre, Penny A. F. Ball, Louise Reynard, Kate L. Loveland, Paul S. Burgoyne, Nabeel A. Affara
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-1 (2019)
Following publication of the original article [1], the following error was reported: The actin control panel in Fig. 3 of this paper is reproduced from Fig. 7 of Touré et al, 2004 [2] by kind permission of the Genetics Society of America. Touré et
Externí odkaz:
https://doaj.org/article/2efd19ffbef44fa18f17703ba7741e86
Autor:
Julie Cocquet, Peter J I Ellis, Yasuhiro Yamauchi, Shantha K Mahadevaiah, Nabeel A Affara, Monika A Ward, Paul S Burgoyne
Publikováno v:
PLoS Biology, Vol 7, Iss 11, p e1000244 (2009)
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR). Several genes have been identified on MSYq, b
Externí odkaz:
https://doaj.org/article/fb880ebd02244839baabfc823f4e2d47
Autor:
Nabeel A. Affara, Julie Cocquet, Shantha K. Mahadevaiah, Paul S. Burgoyne, Peter J. I. Ellis, Daniel Vaiman
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008290 (2019)
PLoS Genetics
PLoS Genetics
Intragenomic conflicts arise when a genetic element favours its own transmission to the detriment of others. Conflicts over sex chromosome transmission are expected to have influenced genome structure, gene regulation, and speciation. In the mouse, t
Autor:
Paul S. Burgoyne, Arthur P. Arnold
Publikováno v:
Biology of Sex Differences
In animals with heteromorphic sex chromosomes, all sex differences originate from the sex chromosomes, which are the only factors that are consistently different in male and female zygotes. In mammals, the imbalance in Y gene expression, specifically
Publikováno v:
Human Molecular Genetics
During spermatogenesis, germ cells that fail to synapse their chromosomes or fail to undergo meiotic sex chromosome inactivation (MSCI) are eliminated via apoptosis during mid-pachytene. Previous work showed that Y-linked genes Zfy1 and Zfy2 act as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0a578c31cb11c047269668dce3e042
https://kar.kent.ac.uk/58282/1/ddw344.pdf
https://kar.kent.ac.uk/58282/1/ddw344.pdf
Autor:
Julie Cocquet, Nabeel A. Affara, Thomas P. S. Karacs, Obah A. Ojarikre, Áine Rattigan, Monika A. Ward, Jonathan M. Riel, Peter J.I. Ellis, Yasuhiro Yamauchi, Paul S. Burgoyne
Publikováno v:
Molecular Biology of the Cell
Slx and Slxl1 are genes present in multiple copies on the mouse X chromosome. Using transgenically-delivered small interfering RNAs to disrupt their function, we show that Slx and Slxl1 are important for normal sperm differentiation and male fertilit
Autor:
Eleni Panousopoulou, Paul S. Burgoyne, Cihangir Yandim, Richard Festenstein, Alexander Saveliev, Nicky Harker, Mushfika Ahmad, Patrick J. Wijchers
Publikováno v:
Developmental Cell. 19:477-484
SummaryDifferences between males and females are normally attributed to developmental and hormonal differences between the sexes. Here, we demonstrate differences between males and females in gene silencing using a heterochromatin-sensitive reporter
Publikováno v:
Biology of Reproduction. 81:250-257
Deletion analysis has established that genes on the Y chromosome are essential for normal sperm production in humans, mice, and Drosophila. In mice, long-arm deletions have an impact on spermiogenesis, with the most extensive deletions resulting in s
Autor:
Samantha J. Wong, Monika A. Ward, Jonathan M. Riel, Obah A. Ojarikre, Paul S. Burgoyne, Yasuhiro Yamauchi
Publikováno v:
Biology of Reproduction. 81:353-361
The mouse Y chromosome long arm (Yq) comprises approximately 70 Mb of repetitive, male-specific DNA together with a short (0.7-Mb) pseudoautosomal region (PAR). The repetitive non-PAR region (NPYq) encodes genes whose deficiency leads to subfertility
Publikováno v:
Nature Reviews Genetics. 10:207-216
During mammalian meiosis, synapsis of paternal and maternal chromosomes and the generation of DNA breaks are needed to allow reshuffling of parental genes. In mammals errors in synapsis are associated with a male-biased meiotic impairment, which has