Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Paul S. Buckmaster"'
Autor:
D. Colette Williams, Martin Haulena, Sophie Dennison, Lynnette Waugh, Tracey Goldstein, Felicia Nutter, Bill Van Bonn, Vanessa Hoard, Kenneth D. Laxer, Paul S. Buckmaster, Frances M. D. Gulland, Barry Tharp
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
This study was designed to identify abnormalities in the electroencephalograms (EEGs) recorded from stranded California sea lions (Zalophus californianus) with suspected domoic acid (DA) toxicosis. Recordings from animals presenting for non-neurologi
Externí odkaz:
https://doaj.org/article/af5eda8baf474c15b02ea8be2d149b3d
Publikováno v:
Epilepsia. 61:856-867
Objective The present study tested whether ictal onset sites are regions of more severe interneuron loss in epileptic pilocarpine-treated rats, a model of human temporal lobe epilepsy. Methods Local field potential recordings were evaluated to identi
Autor:
Paul S. Buckmaster, Megan Wyeth
Publikováno v:
eNeuro
Temporal lobe epilepsy remains a common disorder with no cure and inadequate treatments, potentially due to an incomplete understanding of how seizures start. CA1 pyramidal cells and many inhibitory interneurons increase their firing rate in the seco
Autor:
Siqin Huang, Hong Jiang, Edward H. Bertram, Chengde Liao, Yanrong Zhang, Emily Abrams, Frezghi Habte, Kevin S. Lee, Haiyan Zhou, Paul S. Buckmaster, Haibo Qu, Max Wintermark, Li Yuan, Kim Butts Pauly
Publikováno v:
Ultrasound in Medicine & Biology. 45:129-136
The goal of this study was to test different combinations of acoustic pressure and doses of quinolinic acid (QA) for producing a focal neuronal lesion in the murine hippocampus without causing unwanted damage to adjacent brain structures. Sixty male
Autor:
Kevin S. Lee, Max Wintermark, Lexuan Qiu, Shivek Narang, Ningrui Li, Frezghi Habte, Yanrong Zhang, Sara Natasha Ghobadi, Edward H. Bertram, Paul S. Buckmaster, Jing Wang, Ai Huang, Olivier Keunen, Qingyi Hou
Publikováno v:
Exp Neurol
Surgery can be highly effective for treating certain cases of drug resistant epilepsy. The current study tested a novel, non-invasive, surgical strategy for treating seizures in a rat model of temporal lobe epilepsy. The surgical approach uses magnet
Publikováno v:
Clinical Neurophysiology. 132:e87
Introduction. Among 16 possible types of ictal onset and offset based on seizure dynamics, the saddle node/homoclinic (SN/SH), which is characterized by ictal Direct Current shift (ictal DC), seems to be predominant across species. We predicted that
Publikováno v:
Journal of Comparative Neurology. 525:2592-2610
Epilepsy occurs in one of 26 people. Temporal lobe epilepsy is common and can be difficult to treat effectively. It can develop after brain injuries that damage the hippocampus. Multiple pathophysiological mechanisms involving the hippocampal dentate
Autor:
Frances M. D. Gulland, Ariana Lopez, Raisa Glabman, Cara L. Field, Paul S. Buckmaster, Starr Cameron, Emily Abrams, Shawn P. Johnson
Publikováno v:
J Comp Neurol
One in 26 people develop epilepsy and in these temporal lobe epilepsy (TLE) is common. Many patients display a pattern of neuron loss called hippocampal sclerosis. Seizures usually start in the hippocampus but underlying mechanisms remain unclear. On
Publikováno v:
Neurotoxicology. 66
Harmful blooms of domoic acid (DA)-producing algae are a problem in oceans worldwide. DA is a potent glutamate receptor agonist that can cause status epilepticus and in survivors, temporal lobe epilepsy. In mice, one-time low-dose in utero exposure t
Publikováno v:
Hippocampus. 25:594-604
Numerous hypotheses of temporal lobe epileptogenesis have been proposed, and several involve hippocampal mossy cells. Building on previous hypotheses we sought to test the possibility that after epileptogenic injuries surviving mossy cells develop in