Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Paul S Larson"'
Autor:
Nathan C Rowland, Suneil K Kalia, Lorraine V Kalia, Paul S Larson, Daniel A Lim, Krystof S Bankiewicz
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Parkinson's disease (PD) is a complex neurodegenerative disorder that is currently managed using a broad array of symptom-based strategies. However, targeting its molecular origins represents the potential to discover disease-modifying therapies. Dee
Externí odkaz:
https://doaj.org/article/5c1d157fd65345ccbe979325f4cf010a
Autor:
Genevieve Basich-Pease, Natalya Slepneva, Adam C. Frank, Tenzin Norbu, Melanie A. Morrison, Leo P. Sugrue, Paul S. Larson, Philip A. Starr, A. Moses Lee
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2024)
Deep brain stimulation (DBS) of the anterior limb of the internal capsule (ALIC) has been used to treat refractory obsessive-compulsive disorder (OCD) and depression, but outcomes are variable, with some patients not responding to this form of invasi
Externí odkaz:
https://doaj.org/article/c677b1eb8ddf488db9bfce74a612fa1e
Autor:
Paul S. Larson
This is an account of the actions taken by the residents of Bethlehem, Pennsylvania to create a local amateur society singing the music of J. S.Bach and to develop it into a choir of international importance. Singers, instrumentalists, industrialists
Autor:
Adam C. Frank, Katherine W. Scangos, Paul S. Larson, Tenzin Norbu, Anthony T. Lee, A Moses Lee
Publikováno v:
Brain Stimulation, Vol 14, Iss 4, Pp 1002-1004 (2021)
Externí odkaz:
https://doaj.org/article/2e47c69fa3684d95840617fd28dc8eaf
Autor:
Chengyuan Wu, Sean J. Nagel, Rahul Agarwal, Monika Pötter-Nerger, Wolfgang Hamel, Ashwini D. Sharan, Allison T. Connolly, Binith Cheeran, Paul S. Larson
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objective: There have been significant improvements in the design and manufacturing of deep brain stimulation (DBS) systems, but no study has considered the impact of modern systems on complications. We sought to compare the relative occurrence of re
Externí odkaz:
https://doaj.org/article/551150811a1947bd8086fdefcddaf82a
Publikováno v:
Movement Disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::170253700a62fcf2fed7015573626154
https://doi.org/10.1002/mds.29406
https://doi.org/10.1002/mds.29406
Autor:
Marin E. Thompson, Andreas Meier, Elisabeth M. Fine, Amber D. Van Laar, R. Mark Richardson, Paul S. Larson, Omar Khwaja, Grace S. Liang, Chunming Li, Madeline L. Pfau, Chadwick W. Christine, Krystof S. Bankiewicz, Eiry Roberts, Josh R. Rodman
Publikováno v:
Neurology. 98:e40-e50
Background and ObjectivesTo report final, 36-month safety and clinical outcomes from the PD-1101 trial of NBIb-1817 (VY-AADC01) in participants with moderately advanced Parkinson disease (PD) and motor fluctuations.MethodsPD-1101 was a phase 1b, open
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6be78e5799ceef94901ce02eb3ca928a
https://doi.org/10.1212/wnl.0000000000012952
https://doi.org/10.1212/wnl.0000000000012952
Autor:
Paul S. Larson
Publikováno v:
Journal of Parkinson's Disease
A number of cell transplantation and gene therapy trials have been performed over the last three decades in an effort to restore function in Parkinson’s disease. Much has been learned about optimizing delivery methods for these therapeutics. This i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8dd89521b260d946fc2e6e8e74f2dc9
https://doi.org/10.3233/jpd-212710
https://doi.org/10.3233/jpd-212710
Autor:
Neha Seth, Amy Minnema, Miguel Hernandez Pampaloni, Amy Viehoever, Toni S. Pearson, Waldy San Sebastian, Ana Grijalvo-Perez, Shannon Lundy, Erin Smith, Russell R. Lonser, Krystof S. Bankiewicz, Jill Imamura-Ching, J. Bradley Elder, Jeffrey R. Leonard, Youngho Seo, Jill C. Heathcock, Keith Hyland, Gardenia de Oliveira Barbosa, Paul S. Larson, Alex J. Fay, Nalin Gupta
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare genetic disorder characterized by deficient synthesis of dopamine and serotonin. It presents in early infancy, and causes severe developmental disability and lifelong motor, behavioral,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1b27ada774d9679081a711f5a04705
https://doaj.org/article/77c5fbe7e4b84dc5bdd76784b47254d0
https://doaj.org/article/77c5fbe7e4b84dc5bdd76784b47254d0
Autor:
Chadwick W. Christine, R. Mark Richardson, Elisabeth M. Fine, Omar S. Khwaja, Grace S. Liang, Andreas Meier, Eiry W. Roberts, Krystof Bankiewicz, Paul S. Larson
Publikováno v:
Neurology. 99(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d124f48135741674a58cdcd7eb6df376
https://pubmed.ncbi.nlm.nih.gov/35940895
https://pubmed.ncbi.nlm.nih.gov/35940895