Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Paul S Jeng"'
Autor:
Akane Inoue-Yamauchi, Paul S. Jeng, Kwanghee Kim, Hui-Chen Chen, Song Han, Yogesh Tengarai Ganesan, Kota Ishizawa, Sylvia Jebiwott, Yiyu Dong, Maria C. Pietanza, Matthew D. Hellmann, Mark G. Kris, James J. Hsieh, Emily H. Cheng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Small cell lung cancer cells (SCLC) are differentially sensitive to inhibitors of the BCL-2 family. Here the authors analyse the response to BH3 mimetics in SCLC, delineate patterns of expression of apoptotic proteins correlated with differential sen
Externí odkaz:
https://doaj.org/article/a5d834b769b2400b86f4baf0dda324e5
Publikováno v:
Current Opinion in Physiology. 3:71-81
Mitochondria play key roles in mammalian apoptosis, a highly regulated genetic program of cell suicide. Multiple apoptotic signals culminate in mitochondrial outer membrane permeabilization (MOMP), which not only couples the mitochondria to the activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ef09fee4e570ac4225499672aac918
https://doi.org/10.1016/j.cophys.2018.03.005
https://doi.org/10.1016/j.cophys.2018.03.005
Autor:
Scott R. Kennedy, Wenjing Su, Anna Bialik, Yiyu Dong, Gunes Gundem, Paul S Jeng, Steve Stirdivant, Ying-Bei Chen, A. Ari Hakimi, Ed Reznik, James J. Hsieh, Zachary P. Tolstyka, Jonathan A. Coleman, Jake G. Hoekstra, Philip Jonsson, Jie Tang, Jianing Xu, Francisco Sanchez-Vega, Li Zhang, Satish K. Tickoo, Chad J. Creighton, Elli Papaemmanuil, Daniel M. Kremer, Ho-Joon Lee, Costas A. Lyssiotis, Chris Sander, Paul Russo, Jozefina Casuscelli, Victor E. Reuter, Peter Sajjakulnukit, Judy Sarungbam, Nikolaus Schultz, Emily H. Cheng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4c75b48f89c54963a98d4bf240269e1
https://doi.org/10.7554/elife.38986.025
https://doi.org/10.7554/elife.38986.025
Autor:
Yiyu Dong, Nikolaus Schultz, Ying-Bei Chen, Jonathan A. Coleman, Jianing Xu, Jake G. Hoekstra, Emily H. Cheng, Chris Sander, Li Zhang, Elli Papaemmanuil, James J. Hsieh, Jozefina Casuscelli, Daniel M. Kremer, Eduard Reznik, Ho-Joon Lee, Steve Stirdivant, Francisco Sanchez-Vega, Wenjing Su, Paul S Jeng, A. Ari Hakimi, Chad J. Creighton, Anna Bialik, Scott R. Kennedy, Victor E. Reuter, Judy Sarungbam, Peter Sajjakulnukit, Satish K. Tickoo, Philip Jonsson, Jie Tang, Costas A. Lyssiotis, Zachary P. Tolstyka, Paul Russo, Gunes Gundem
Publikováno v:
eLife, Vol 8 (2019)
While genomic sequencing routinely identifies oncogenic alterations for the majority of cancers, many tumors harbor no discernable driver lesion. Here, we describe the exceptional molecular phenotype of a genomically quiet kidney tumor, clear cell pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184aeab01060500759dca2ad8507f813
https://elifesciences.org/articles/38986
https://elifesciences.org/articles/38986
Autor:
Paul S, Jeng, Emily H, Cheng
Publikováno v:
Nature chemical biology. 9(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4df26b0b68b2022fce26e9d8b861fd3
https://pubmed.ncbi.nlm.nih.gov/23603658
https://pubmed.ncbi.nlm.nih.gov/23603658
Autor:
Emily H. Cheng, Paul S Jeng
Publikováno v:
Nature Chemical Biology. 9:351-352
BCL-XL and other anti-apoptotic BCL-2 family proteins serve as guardians of cellular survival. A new selective small-molecule inhibitor of BCL-XL is developed to promote apoptosis in cancers that are addicted to BCL-XL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74b58180252436efe9a66e0a4fb60441
https://doi.org/10.1038/nchembio.1256
https://doi.org/10.1038/nchembio.1256