Výsledky vyhledávání - "Paul S Fichtinger"

Akademický článek

Comparison of IL-33 and IL-5 family mediated activation of human eosinophils.

Autor: Evelyn L Angulo, Elizabeth M McKernan, Paul S Fichtinger, Sameer K Mathur

Publikováno v: PLoS ONE, Vol 14, Iss 9, p e0217807 (2019)

Eosinophils are the prominent inflammatory cell involved in allergic asthma, atopic dermatitis, eosinophilic esophagitis, and hypereosinophilic syndrome and are found in high numbers in local tissue and/or circulating blood of affected patients. Ther

Externí odkaz: https://doaj.org/article/2f10de51ba88415eab09cb8c771f6780

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An open microfluidic coculture model of fibroblasts and eosinophils to investigate mechanisms of airway inflammation

Autor: Yuting Zeng, Xiaojing Su, Meg G. Takezawa, Paul S. Fichtinger, Ulri N. Lee, Jeffery W. Pippin, Stuart J. Shankland, Fang Yun Lim, Loren C. Denlinger, Nizar N. Jarjour, Sameer K. Mathur, Nathan Sandbo, Erwin Berthier, Stephane Esnault, Ksenija Bernau, Ashleigh B. Theberge

Publikováno v: Frontiers in bioengineering and biotechnology. 10

Interactions between fibroblasts and immune cells play an important role in tissue inflammation. Previous studies have found that eosinophils activated with interleukin-3 (IL-3) degranulate on aggregated immunoglobulin G (IgG) and release mediators t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6b56abfb365b6a581b750bbe4f4d43
https://pubmed.ncbi.nlm.nih.gov/36246374

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Orosomucoid-like 3 Supports Rhinovirus Replication in Human Epithelial Cells

Autor: Jin Wen Tan, Joshua J. Coon, Thiruchelvi R. Reddy, Yury A. Bochkov, Katherine A. Overmyer, Yi-Ping Liu, Christopher Lopez, Paul S. Fichtinger, Jennifer E Gumperz, James E. Gern, Jens C. Eickhoff, Nicholas A Zumwalde, Tianchen Hu, Sameer K. Mathur, Judith A. Smith

Publikováno v: American Journal of Respiratory Cell and Molecular Biology

Polymorphism at the 17q21 gene locus and wheezing responses to rhinovirus (RV) early in childhood conspire to increase the risk of developing asthma. However, the mechanisms mediating this gene-environment interaction remain unclear. In this study, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6d8f9091c7cfa3ae7f45eabe3060c7
https://doi.org/10.1165/rcmb.2019-0237oc

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The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions

Autor: Steve N. Georas, Rosalind J. Wright, Anastasia Ivanova, Elliot Israel, Lisa M. LaVange, Praveen Akuthota, Tara F. Carr, Loren C. Denlinger, Merritt L. Fajt, Rajesh Kumar, Wanda K. O’Neal, Wanda Phipatanakul, Stanley J. Szefler, Mark A. Aronica, Leonard B. Bacharier, Allison J. Burbank, Mario Castro, Laura Crotty Alexander, Julie Bamdad, Juan Carlos Cardet, Suzy A.A. Comhair, Ronina A. Covar, Emily A. DiMango, Kim Erwin, Serpil C. Erzurum, John V. Fahy, Jonathan M. Gaffin, Benjamin Gaston, Lynn B. Gerald, Eric A. Hoffman, Fernando Holguin, Daniel J. Jackson, John James, Nizar N. Jarjour, Nicholas J. Kenyon, Sumita Khatri, John P. Kirwan, Monica Kraft, Jerry A. Krishnan, Andrew H. Liu, Mark C. Liu, M. Alison Marquis, Fernando Martinez, Jacob Mey, Wendy C. Moore, James N. Moy, Victor E. Ortega, David B. Peden, Emily Pennington, Michael C. Peters, Kristie Ross, Maria Sanchez, Lewis J. Smith, Ronald L. Sorkness, Michael E. Wechsler, Sally E. Wenzel, Steven R. White, Joe Zein, Amir A. Zeki, Patricia Noel, Dean Billheimer, Eugene R. Bleecker, Emily Branch, Michelle Conway, Cori Daines, Isaac Deaton, Alexandria Evans, Paige Field, Dave Francisco, Annette T. Hastie, Bob Hmieleski, Jeffrey O. Krings, Yanqin Liu, Janell L. Merchen, Deborah A. Meyers, Nirushan Narendran, Stephen P. Peters, Anna Pippins, Matthew A. Rank, Ronald Schunk, Raymond Skeps, Benjamin Wright, Tina M. Banzon, Lisa M. Bartnikas, Sachin N. Baxi, Vishwanath Betapudi, Isabelle Brick, Conor Brockway, Thomas B. Casale, Kathleen Castillo-Ruano, Maria Angeles Cinelli, Elena Crestani, Amparito Cunningham, Megan Day-Lewis, Natalie Diaz-Cabrera, Angela DiMango, Brittany Esty, Eva Fandozzi, Jesse Fernandez, Elizabeth Fitzpatrick, Victoria E. Forth, Katarina Gentile, David Gubernick, Seyni Gueye-Ndiaye, Sigfus Gunnlaagsson, Marissa Hauptmann, Stephanie N. Hudey, Donya S. Imanirad, Tiffani Kaage, Nicholas Kolinsky, Brenna LaBere, Peggy Sue Lai, Meghan Le, Dennis K. Ledford, Richard Lockey, Margee Louisias, Andrew J. Macginnitie, Michelle C. Maciag, Allison O’Neill, Amber N. Pepper, Perdita Permaul, Mya Pugh, Dianna Queheillalt, Tarnjot Saroya, William Sheehan, Catherine Smith, Carmela Socolovsky, Else Treffeisen, Lorenzo Trippa, Abigail Tulchinsky, Christina Yee, Tina Carter, Jun Fu, Vanessa Garcia, Jenny Hixon, Carly Jackson, Yuan Ji, Ravi Kalhan, Opinderjit Kaur, Grace Li, Melanie M. Makhija, Spring Maleckar, Edward T. Naureckas, Anju T. Peters, Valerie Press, Mehreen Qureshi, Paul A. Reyfman, Sharon R. Rosenberg, Dominika Ryba, Jianrong Sheng, Ben Xu, Rafeul Alam, Darci Anderson, Sonya Belimezova, Jennifer Bitzan, Geoffrey Chupp, Brian J. Clark, Lauren Cohn, Margaret Hope Cruse, Jean Estrom, Leah Freid, Jose Gomez Villalobos, Nicole Grant, Vamsi P. Guntur, Carole Holm, Christena Kolakowski, Laurie A. Manka, Naomi Miyazawa, Juno Pak, Diana M. Pruitt, Sunita Sharma, Allen D. Stevens, Kisori Thomas, Brooke Tippin, Karissa Valente, Cynthia L. Wainscoat, Michael P. White, Daniel Winnica, Shuyu Ye, Pamela L. Zeitlin, Julia Bach, Joshua Brownell, Lauren Castro, Julie DeLisa, Sean B. Fain, Paul S. Fichtinger, Heather Floerke, James E. Gern, Vinay Goswamy, Jenelle Grogan, Wendy Hasse, Rick L. Kelley, Danika Klaus, Stephanie LaBedz, Paige Lowell, Andrew Maddox, Sameer K. Mathur, Amanda McIntyre, Lourdes M. Norwick, Sharmilee M. Nyenhuis, Matthew J. O’Brien, Tina Palas, Andrea A. Pappalardo, Mark Potter, Sima K. Ramratnam, Daniel L. Rosenberg, Eric M. Schauberger, Mark L. Schiebler, Angela Schraml, Mohamed Taki, Matthew C. Tattersall, Jissell Torres, Lori Wollet, Simon Abi-Saleh, Lisa Bendy, Larry Borish, James F. Chmiel, Aska Dix, Lisa France, Rebecca Gammell, Adam Gluvna, Brittany Hirth, Bo Hu, Elise Hyser, Kirsten M. Kloepfer, Michelle Koo, Nadia L. Krupp, Monica Labadia, Joy Lawrence, Laurie Logan, Angela Marko, Brittany Matuska, Deborah Murphy, Rachel Owensby, Erica A. Roesch, Don B. Sanders, Jackie Sharp, W. Gerald Teague, Laura Veri, Kristin Wavell Shifflett, Matt Camiolo, Sarah Collins, Jessa Demas, Courtney Elvin, Marc C. Gauthier, Melissa Ilnicki, Jenn Ingram, Lisa Lane, Seyed Mehdi Nouraie, John B. Trudeau, Michael Zhang, Jeffrey Barry, Howard Brickner, Janelle Celso, Matejka Cernelc-Kohan, Damaris Diaz, Ashley Du, Sonia Jain, Neiman Liu, Yusife Nazir, Julie Ryu, Pandurangan Vijayanand, Rogelio Almario, Ariana Baum, Kellen Brown, Marilynn H. Chan, Barbara Gale, Angela Haczku, Richart W. Harper, Raymond Heromin, Celeste Kivler, Brooks T. Kuhn, Ngoc P. Ly, Paula McCourt, Xavier Orain, Audrey Plough, Karla Ramirez, Ellese Roberts, Michael Schivo, Amisha Singapuri, Tina Tham, Daniel Tompkins, Patricia Michelle Twitmyer, Jade Vi, Jarron Atha, Jennifer Bedard, Jonathan S. Boomer, Andrew Chung, Vanessa Curtis, Chase S. Hall, Emily Hart, Fatima Jackson, Pamela Kemp, Sharli Maxwell, Maggie Messplay, Crystal Ramirez, Brynne Thompson, Ashley Britt, Hope Bryan, Nathan M. Gotman, Yue Jiang, Michael R. Kosorok, David T. Mauger, Kelsey Meekins, Jeanette K. Mollenhauer, Sarah Moody, Cheyanne Ritz, Stefanie Schwartz, Chalmer Thomlinson, Nicole Wilson

Publikováno v: The Journal of allergy and clinical immunology, vol 149, iss 2
J Allergy Clin Immunol

Asthma is a heterogeneous disease, with multiple underlying inflammatory pathways and structural airway abnormalities that impact disease persistence and severity. Recent progress has been made in developing targeted asthma therapeutics, especially f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03c5f5d8b51cbaec71bb4af5e61e502
https://escholarship.org/uc/item/4n8620m5

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Omalizumab for treatment of idiopathic angioedema

Autor: Vinay P, Goswamy, Kristine E, Lee, Elizabeth M, McKernan, Paul S, Fichtinger, Sameer K, Mathur, Ravi K, Viswanathan

Publikováno v: Annals of Allergy, Asthma & Immunology. 129:605-611.e1

Omalizumab has been found to improve outcomes in patients with chronic spontaneous urticaria (CSU). Idiopathic angioedema (IAE) is increasingly being recognized as a condition with similar underlying mechanisms as CSU and a form of CSU. We hypothesiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3414aac71cc17d5749f5ff567718a14d
https://doi.org/10.1016/j.anai.2022.07.017

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