Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Paul S, Dobbin"'
Autor:
Paul S, Dobbin, Louise H, Warren, Nicola J, Cook, Alastair G, McEwan, Anne K, Powell, David J, Richardson
Publikováno v:
Microbiology (Reading, England). 142(4)
The photosynthetic proteobacterium
Autor:
Cherry A. Davis, Colin R. Andrew, Amy E. Servid, Andreea Manole, Paul S. Dobbin, Alison L. McKay, Michael A. Hough, Elizabeth M. Garton
Publikováno v:
Biochemistry. 54:3320-3327
Five-coordinate heme nitrosyl complexes (5cNO) underpin biological heme-NO signal transduction. Bacterial cytochromes c' are some of the few structurally characterized 5cNO proteins, exhibiting a distal to proximal 5cNO transition of relevance to NO
Publikováno v:
Journal of medicinal chemistry. 60(8)
Photodynamic therapy (PDT) is a promising treatment strategy for malignant and nonmalignant lesions. 5-Aminolaevulinic acid (ALA) is used as a precursor of the photosensitizer, protoporphyrin IX (PpIX), in dermatology and urology. However, the effect
Autor:
Paul S. Dobbin, Sinan Battah, Haydée Fukuda, Alexander J. MacRobert, Adriana Casas, Alcira Batlle, Lorena Rodriguez, Gabriela Di Venosa
Publikováno v:
Journal of Controlled Release. 135:136-143
The use of endogenous protoporphyrin IX (PpIX) after administration of 5-aminolaevulinic acid (ALA) has led to many applications in photodynamic therapy (PDT). However the efficacy of ALA-PDT is sub-optimal for thicker tumours and improved ALA delive
Autor:
Christine Edwards, Adriana Casas, Alexander J. MacRobert, Alcira Batlle, Sophie O’Neill, Sherina Balaratnam, Sinan Battah, Paul S. Dobbin
Publikováno v:
Molecular Cancer Therapeutics. 6:876-885
Intracellular porphyrin generation following administration of 5-aminolaevulinic acid (5-ALA) has been widely used in photodynamic therapy. However, cellular uptake of 5-ALA is limited by its hydrophilicity, and improved means of delivery are therefo
Autor:
Alcira Batlle, Sinan Battah, Alexander J. MacRobert, Adriana Casas, Gabriela Di Venosa, Lorena Rodriguez, Paul S. Dobbin
Publikováno v:
British Journal of Pharmacology. 147:825-833
The porphyrin precursor 5-aminolevulinic acid (ALA) is being widely used in photodynamic therapy of cancer. Improvement in ALA delivery has been sought through the use of ALA derivatives, in particular the esterification of ALA with aliphatic alcohol
Autor:
Sinan Battah, Sherina Balaratnam, Paul S. Dobbin, Sophie O’Neill, Christine Edwards, Alexander J. MacRobert
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 38:1382-1392
Intracellular porphyrin generation following administration of 5-aminolaevulinic acid has been widely used in photodynamic therapy for a range of malignant and certain non-malignant lesions. However, cellular uptake of 5-aminolaevulinic acid is limit
Autor:
Haydée Fukuda, Gabriela Di Venosa, Alexander J. MacRobert, Adriana Casas, Alcira Batlle, Paul S. Dobbin, Sinan Battah
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 38:82-91
Photodynamic therapy is a treatment for malignant and certain non-malignant lesions that involves administration of a photosensitising drug. The use of 5-aminolaevulinic acid-induced porphyrins has become one of the most active fields of photodynamic
Autor:
Harriet E. Seward, Andrew J. Thomson, Katy E. Pitts, Francisca Reyes-Ramírez, David J. Richardson, Paul S. Dobbin
Publikováno v:
Journal of Biological Chemistry. 278:27758-27765
Shewanella oneidensis MR-1 has the metabolic capacity to grow anaerobically using Fe(III) as a terminal electron acceptor. Growth under these conditions results in the de novo synthesis of a number of periplasmic c-type cytochromes, many of which are
Autor:
Andreea Manole, Demet Kekilli, Michael T. Wilson, Paul S. Dobbin, Michael A. Hough, Dimitri A. Svistunenko
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 20(4)
The cytochromes c′ (CYTcp) are found in denitrifying, methanotrophic and photosynthetic bacteria. These proteins are able to form stable adducts with CO and NO but not with O2. The binding of NO to CYTcp currently provides the best structural model