Zobrazeno 1 - 10
of 538
pro vyhledávání: '"Paul Roach"'
Autor:
Ayanthi Wijewardene, Matti Gild, Lyndal Tacon, Venessa Tsang, Anthony J Gill, Anthony Robert Glover, Mark Sywak, Stan Sidhu, Bruce Robinson, Paul Roach, Geoffrey Schembri, Jeremy Hoang, Roderick Clifton-Bligh
Publikováno v:
Endocrine Connections, Vol 13, Iss 11, Pp 1-7 (2024)
Background: Noise, an unwanted variability in judgment, is ubiquitous in medicine, including in the prescription of radioactive iodine (RAI). Building upon our recently developed predictive risk model, we created an online clinical support tool to fa
Externí odkaz:
https://doaj.org/article/2f1faf20e1fd48eea8c1b375e35cdf9b
Publikováno v:
Biomaterials and Biosystems, Vol 15, Iss , Pp 100099- (2024)
The bone-cartilage interface is defined by a unique arrangement of cells and tissue matrix. Injury to the interface can contribute to the development of arthritic joint disease. Attempts to repair osteochondral damage through clinical trials have gen
Externí odkaz:
https://doaj.org/article/b691898f9dd44e22a4951bcd93f9e98b
Autor:
Eng-Siew Koh, Mustafa Khasraw, Elizabeth H Barnes, Kyle M Walsh, Mark Rosenthal, Rodney J Hicks, Farshad Foroudi, Hui K Gan, Anna K Nowak, Dale L Bailey, Paul Roach, Arian Lasocki, Robyn Leonard, Roel Verhaak, Andrew M Scott, Alisha Moore, Bradford A Moffat, Clare Senko, Roslyn J Francis, Martin Ebert, Sze Ting Lee, Eddie Lau, Greg Fitt, Robert Coffey, Richard De Abreu Lourenco, Lucas Adda, Paul A Thomas, Michael Back
Publikováno v:
BMJ Open, Vol 13, Iss 8 (2023)
Introduction Glioblastoma is the most common aggressive primary central nervous system cancer in adults characterised by uniformly poor survival. Despite maximal safe resection and postoperative radiotherapy with concurrent and adjuvant temozolomide-
Externí odkaz:
https://doaj.org/article/d8d21057c5584e9388379c1d9d0c188d
Autor:
Sandhya Moise, Luigi Dolcetti, Francesco Dazzi, Paul Roach, Lee Buttery, Sheila MacNeil, Nick Medcalf
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 50, Iss 1, Pp 168-176 (2022)
Mesenchymal stromal cells (MSCs) show immunosuppressive effects both via cell-to-cell contact (direct) with immune cells and by producing paracrine factors and extracellular vesicles (indirect). A key challenge in delivering this therapeutic effect i
Externí odkaz:
https://doaj.org/article/553c2c08f92940b3af31d4ab98942208
Publikováno v:
BMJ case reports. 15(9)
An adolescent female patient presented with atraumatic left knee pain and limited flexion. MRI demonstrated evidence of a soft tissue lesion abutting the posterior cruciate ligament. Differential diagnosis included pigmented villonodular synovitis (P
Autor:
Itzy E. Morales Pantoja, Lena Smirnova, Alysson R. Muotri, Karl J. Wahlin, Jeffrey Kahn, J. Lomax Boyd, David H. Gracias, Timothy D. Harris, Tzahi Cohen-Karni, Brian S. Caffo, Alexander S. Szalay, Fang Han, Donald J. Zack, Ralph Etienne-Cummings, Akwasi Akwaboah, July Carolina Romero, Dowlette-Mary Alam El Din, Jesse D. Plotkin, Barton L. Paulhamus, Erik C. Johnson, Frederic Gilbert, J. Lowry Curley, Ben Cappiello, Jens C. Schwamborn, Eric J. Hill, Paul Roach, Daniel Tornero, Caroline Krall, Rheinallt Parri, Fenna Sillé, Andre Levchenko, Rabih E. Jabbour, Brett J. Kagan, Cynthia A. Berlinicke, Qi Huang, Alexandra Maertens, Kathrin Herrmann, Katya Tsaioun, Raha Dastgheyb, Christa Whelan Habela, Joshua T. Vogelstein, Thomas Hartung
Publikováno v:
Frontiers in Artificial Intelligence, Vol 6 (2023)
The brain is arguably the most powerful computation system known. It is extremely efficient in processing large amounts of information and can discern signals from noise, adapt, and filter faulty information all while running on only 20 watts of powe
Externí odkaz:
https://doaj.org/article/aebc0f0cd878418ebed9205a612b1932
Autor:
Lewis M Dowling, Paul Roach, Eirik A Magnussen, Achim Kohler, Srinivas Pillai, Daniel G van Pittius, Ibraheem Yousef, Josep Sulé-Suso
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0289824 (2023)
The management of cancer patients has markedly improved with the advent of personalised medicine where treatments are given based on tumour antigen expression amongst other. Within this remit, liquid biopsies will no doubt improve this personalised c
Externí odkaz:
https://doaj.org/article/8e189ac929754269ab4b7783929414ab
Autor:
Jacob Ranjbar, Wanjiku Njoroge, Jonathan M. Gibbins, Paul Roach, Ying Yang, Alan G. S. Harper
Publikováno v:
Gels, Vol 9, Iss 6, p 477 (2023)
Current in vitro thrombosis models utilise simplistic 2D surfaces coated with purified components of the subendothelial matrix. The lack of a realistic humanised model has led to greater study of thrombus formation in in vivo tests in animals. Here w
Externí odkaz:
https://doaj.org/article/c0ae940eef0c494291826dc3e8a3c484
Autor:
Dhanusha Sabanathan, Douglas Campbell, Vicki Velonas, Sandra Wissmueller, Hubert Mazure, Marko Trifunovic, Pirooz Poursoltan, Kevin Ho-Shon, Tiffany Mackay, Maria Lund, Yanling Lu, Paul Roach, Dale Bailey, Bradley Walsh, David Gillatt, Howard Gurney
Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 9, Iss 2, Pp 86-100 (2021)
Objective(s): Miltuximab® is a chimeric antibody targeting Glypican-1 (GPC-1), a cell surface antigen which is overexpressed in solid cancers. Miltuximab® has shown promising safety and efficacy in radioimmunotherapy models of prostate cancer. This
Externí odkaz:
https://doaj.org/article/e54133442db347f2aa83af2e911eee7d
Publikováno v:
ACS Omega, Vol 6, Iss 30, Pp 19901-19910 (2021)
Externí odkaz:
https://doaj.org/article/5e5ec8ef73cb4d2ca65e092f90451981