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pro vyhledávání: '"Paul Rivollier"'
Autor:
Mihajlo Todorovic, Paul Rivollier, Antonio A. W. L. Wong, Zhou Wang, Alla Pryyma, Tuan Trung Nguyen, Kayla C. Newell, Juliette Froelich, David M. Perrin
Publikováno v:
Journal of medicinal chemistry. 65(15)
For 70 years, α-amanitin, the most cytotoxic peptide in its class, has been without a synthetic rival; through synthesis, we address the structure-activity relationships to inform the design of new amatoxins and disclose analogues that are more cyto