Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Paul R. Stabach"'
Autor:
Kris Dammen-Brower, Paige Epler, Stanley Zhu, Zachary J. Bernstein, Paul R. Stabach, Demetrios T. Braddock, Jamie B. Spangler, Kevin J. Yarema
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Almost all therapeutic proteins are glycosylated, with the carbohydrate component playing a long-established, substantial role in the safety and pharmacokinetic properties of this dominant category of drugs. In the past few years and moving forward,
Externí odkaz:
https://doaj.org/article/3775269b6eef48569bd03841192d16ba
Autor:
Paul R. Stabach, Kristin Zimmerman, Aaron Adame, Dillon Kavanagh, Christopher T. Saeui, Christian Agatemor, Shawn Gray, Wenxiang Cao, Enrique M. De La Cruz, Kevin J. Yarema, Demetrios T. Braddock
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 362-372 (2021)
Enzyme replacement with ectonucleotide pyrophosphatase phospodiesterase‐1 (ENPP1) eliminates mortality in a murine model of the lethal calcification disorder generalized arterial calcification of infancy. We used protein engineering, glycan optimiz
Externí odkaz:
https://doaj.org/article/eb3329ba4a5240e181f00b874aa1535e
Publikováno v:
The FASEB Journal. 36
Autor:
Anenya J. Ansh, Catherine Nester, Christine O'Brien, Paul R. Stabach, Sae‐Il Murtada, Ethan R. Lester, Gus Khursigara, Liz Molloy, Thomas O. Carpenter, Carlos R. Ferreira, Demetrios T. Braddock
Publikováno v:
The FASEB Journal. 36
Autor:
Thomas O. Carpenter, Björn Busse, Dillon Kavanagh, Simon von Kroge, Paul R. Stabach, Demetrios T. Braddock, Mark C. Horowitz, Thorsten Schinke, Nathan D. Maulding, Michael Amling, Kristin Zimmerman, Ralf Oheim, Uwe Kornak, Steven M. Tommasini, Julian Stürznickel, David B. Thompson
Publikováno v:
Journal of Bone and Mineral Research
Biallelic ENPP1 deficiency in humans induces generalized arterial calcification of infancy (GACI) and/or autosomal recessive hypophosphatemic rickets type 2 (ARHR2). The latter is characterized by markedly increased circulating FGF23 levels and renal
Autor:
Carlos R. Ferreira, Anenya Jai Ansh, Catherine Nester, Christine O'Brien, Paul R. Stabach, Sae‐Il Murtada, Ethan R. Lester, Gus Khursigara, Liz Molloy, Thomas O. Carpenter, Demetrios T. Braddock
Publikováno v:
J Bone Miner Res
Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) deficiency leads to cardiovascular calcification in infancy, fibroblast growth factor 23 (FGF23)-mediated hypophosphatemic rickets in childhood, and osteomalacia in adulthood. Excessive enthe
Autor:
Yuan You, Hong Liu, Gil Mor, Anthony Maxwell, Jiwon Jeong, Brett D. Lindenbach, Demetrios T. Braddock, Jiahui Ding, Paulomi Aldo, Xuemin Qiu, Paul R. Stabach, Cai M. Roberts, Ai-Hua Liao
Publikováno v:
EMBO Rep
Zika virus is a positive-sense single-stranded RNA virus, which can be transmitted across the placenta and has adverse effects on fetal development during pregnancy. The severity of these complications highlights the importance of prevention and trea
Autor:
Michael C. Stankewich, Jun-Ping Bai, Paul R. Stabach, Saaim Khan, Winston J.T. Tan, Alexei Surguchev, Lei Song, Jon S. Morrow, Joseph Santos-Sacchi, Dhasakumar S. Navaratnam
Publikováno v:
Hearing Research. 423:108564
Reports have proposed a putative role for βV spectrin in outer hair cells (OHCs) of the cochlea. In an ongoing investigation of the role of the cytoskeleton in electromotility, we tested mice with a targeted exon deletion of βV spectrin (Spnb5), an
Autor:
Ai-Hua Liao, Jiahui Ding, Demetrios T. Braddock, Jiwon Jeong, Xuemin Qiu, Anthony Maxwell, Hong Liu, Yuan You, Brett D. Lindenbach, Cai M. Roberts, Paul R. Stabach, Paulomi Aldo, Mor Gil
Zika virus is a positive-sense single-stranded RNA virus, which can be transmitted across the placenta and leads to adverse effects on fetal development during pregnancy. The severity of these complications highlights the importance of prevention and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b46f89ce47dbaefe7e9edb321e307ff3
https://doi.org/10.1101/2021.01.13.426624
https://doi.org/10.1101/2021.01.13.426624
Autor:
Ralf Oheim, Paul R. Stabach, Dillon Kavanagh, Steven M. Tommasini, Thomas O. Carpenter, Demetrios T. Braddock, Simon von Kroge, Kristin Zimmerman
Publikováno v:
Bone Reports, Vol 13, Iss, Pp 100692-(2020)