Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Paul R. Sanders"'
Autor:
Khayriyyah Mohd Hanafiah, Norsyahida Arifin, Paul R. Sanders, Nurulhasanah Othman, Mary L. Garcia, David A. Anderson
Publikováno v:
Vaccines, Vol 7, Iss 3, p 80 (2019)
Tuberculosis (TB) is ranked among the top 10 causes of death worldwide. New biomarker-based serodiagnostics and vaccines are unmet needs stalling disease control. Antigen 60 (A60) is a thermostable mycobacterial complex typically purified from Bacill
Externí odkaz:
https://doaj.org/article/cf62994051e34924b836aec10569da42
Autor:
Hayley E. Bullen, Paul R. Sanders, Madeline G. Dans, Thorey K. Jonsdottir, David T. Riglar, Oliver Looker, Catherine S. Palmer, Betty Kouskousis, Sarah C. Charnaud, Tony Triglia, Mikha Gabriela, Molly Parkyn Schneider, Jo‐Anne Chan, Tania F. de Koning‐Ward, Jake Baum, James W. Kazura, James G. Beeson, Alan F. Cowman, Paul R. Gilson, Brendan S. Crabb
Publikováno v:
Molecular Microbiology. 117:1245-1262
Infection with Plasmodium falciparum parasites results in approximately 627,000 deaths from malaria annually. Key to the parasite's success is their ability to invade and subsequently grow within human erythrocytes. Parasite proteins involved in para
Autor:
Mauro F Azevedo, Catherine Q Nie, Brendan Elsworth, Sarah C Charnaud, Paul R Sanders, Brendan S Crabb, Paul R Gilson
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112571 (2014)
Drug discovery is a key part of malaria control and eradication strategies, and could benefit from sensitive and affordable assays to quantify parasite growth and to help identify the targets of potential anti-malarial compounds. Bioluminescence, ach
Externí odkaz:
https://doaj.org/article/e22dc4da0f204f41a369e9e8435d12dc
Autor:
Paul R Sanders, Betty Kouskousis, Thorey K Jonsdottir, Hayley E Bullen, Paul R. Gilson, Natalie A. Counihan, Brendan S. Crabb, Mikha Gabriela, Tania F. de Koning-Ward, Joyanta K Modak
Publikováno v:
Cellular Microbiology
During its intraerythrocytic life cycle, the human malaria parasite Plasmodium falciparum supplements its nutritional requirements by scavenging substrates from the plasma through the new permeability pathways (NPPs) installed in the red blood cell (
Autor:
Damien R. Drew, Brendan S. Crabb, Gretchen Weiss, Paul R. Gilson, James G. Beeson, Paul R Sanders
Publikováno v:
The Journal of Infectious Diseases. 217:498-507
Plasmodium vivax and P. falciparum malaria species have diverged significantly in receptor-ligand interactions and host-cell invasion. One protein common to both is the merozoite invasion ligand AMA1. While the general structure of AMA1 is similar be
Autor:
Mary L Garcia, Paul R Sanders, Norsyahida Arifin, Nurulhasanah Othman, David A. Anderson, Khayriyyah Mohd Hanafiah
Publikováno v:
Vaccines, Vol 7, Iss 3, p 80 (2019)
Vaccines
Volume 7
Issue 3
Vaccines
Volume 7
Issue 3
Tuberculosis (TB) is ranked among the top 10 causes of death worldwide. New biomarker-based serodiagnostics and vaccines are unmet needs stalling disease control. Antigen 60 (A60) is a thermostable mycobacterial complex typically purified from Bacill
Autor:
Brendan S. Crabb, Brendan Elsworth, Paul R Sanders, Sarah C. Charnaud, Leann Tilley, Steven Batinovic, Thomas Nebl, Catherine Q Nie, Ming Kalanon, Hayley E Bullen, Tania F. de Koning Ward, Paul R. Gilson
Publikováno v:
Cellular Microbiology. 18:1551-1569
The Plasmodium translocon for exported proteins (PTEX) has been established as the machinery responsible for the translocation of all classes of exported proteins beyond the parasitophorous vacuolar membrane of the intraerythrocytic malaria parasite.
Autor:
Sarah C. Charnaud, Paul A. Ramsland, Paul R. Gilson, Brendan S. Crabb, Benjamin K. Dickerman, Paul R Sanders
Publikováno v:
Journal of biochemistry. 165(3)
In order to facilitate a number of processes including nutrient acquisition and immune evasion, malaria parasites extensively remodel their host erythrocyte. This remodelling is to a large extent accomplished through protein export, a crucial process
Autor:
Scott A. Chisholm, Benjamin K. Dickerman, Paul R Sanders, Ming Kalanon, Thomas Nebl, Paul R. Gilson, Tania F. de Koning-Ward, Kathryn Matthews
Publikováno v:
The FEBS journal. 285(11)
The pathogenic nature of malaria infections is due in part to the export of hundreds of effector proteins that actively remodel the host erythrocyte. The Plasmodium translocon of exported proteins (PTEX) has been shown to facilitate the trafficking o
Autor:
Greta E. Weiss, Paul R Sanders, Paul R. Gilson, Anubhav Srivastava, Thorey K Jonsdottir, Darren J. Creek, Tania F. de Koning-Ward, Scott A. Chisholm, Brendan S. Crabb, Natalie A. Counihan, Sreejoyee Ghosh, Hayley E Bullen
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Plasmodium falciparum parasites, the causative agents of malaria, modify their host erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and for removal of toxic waste. Here we investigate the contribution of the rhop