Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Paul R. McAdam"'
Autor:
Anne-Catrin Uhlemann, Paul R. McAdam, Sean B. Sullivan, Justin R. Knox, Hossein Khiabanian, Raul Rabadan, Peter R. Davies, J. Ross Fitzgerald, Franklin D. Lowy
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Methicillin-susceptible Staphylococcus aureus (MSSA) accounts for the majority of S. aureus infections globally, and yet surprisingly little is known about its clonal evolution. We applied comparative whole-genome sequencing (WGS) analyses t
Externí odkaz:
https://doaj.org/article/280f93f8f4fa41418531cfdd0d22130f
Autor:
Laura E. Spoor, Paul R. McAdam, Lucy A. Weinert, Andrew Rambaut, Henrik Hasman, Frank M. Aarestrup, Angela M. Kearns, Anders R. Larsen, Robert L. Skov, J. Ross Fitzgerald
Publikováno v:
mBio, Vol 4, Iss 4 (2013)
ABSTRACT The importance of livestock as a source of bacterial pathogens with the potential for epidemic spread in human populations is unclear. In recent years, there has been a global increase in community-associated methicillin-resistant Staphyloco
Externí odkaz:
https://doaj.org/article/e7354c8f5aa84da9b2b11182630efc2c
Autor:
Zineb Mounir, Mark R. Lackner, Shih-Min A. Huang, Yannick Waumans, Mark Kockx, Koen M. Marien, Sarah Lynagh, Paul R. McAdam, Max Bylesjo, Adrian R. Carr, Daniel L. Halligan, Sanjeev Mariathasan, Edward E. Kadel, Kobe C. Yuen, Thomas Holcomb, Shrividhya Srinivasan, Joseph Castillo, Marie-Claire Wagle
supplementary tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35073d94791ff25b6df92ad645e456c1
https://doi.org/10.1158/2326-6066.22543155.v1
https://doi.org/10.1158/2326-6066.22543155.v1
Supplementary Fig 1 from Tumor Fusion Burden as a Hallmark of Immune Infiltration in Prostate Cancer
Autor:
Zineb Mounir, Mark R. Lackner, Shih-Min A. Huang, Yannick Waumans, Mark Kockx, Koen M. Marien, Sarah Lynagh, Paul R. McAdam, Max Bylesjo, Adrian R. Carr, Daniel L. Halligan, Sanjeev Mariathasan, Edward E. Kadel, Kobe C. Yuen, Thomas Holcomb, Shrividhya Srinivasan, Joseph Castillo, Marie-Claire Wagle
TMB, TFB and CRPC scores across individual samples and disease stages and crosscorrelation analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9124389488a6abd15abccd6bbf624d28
https://doi.org/10.1158/2326-6066.22543161.v1
https://doi.org/10.1158/2326-6066.22543161.v1
Autor:
Zineb Mounir, Mark R. Lackner, Shih-Min A. Huang, Yannick Waumans, Mark Kockx, Koen M. Marien, Sarah Lynagh, Paul R. McAdam, Max Bylesjo, Adrian R. Carr, Daniel L. Halligan, Sanjeev Mariathasan, Edward E. Kadel, Kobe C. Yuen, Thomas Holcomb, Shrividhya Srinivasan, Joseph Castillo, Marie-Claire Wagle
Prostate cancer is the second leading cause of cancer-related death in men. Despite having a relatively lower tumor mutational burden than most tumor types, multiple gene fusions such as TMPRSS2:ERG have been characterized and linked to more aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e25bc093bffce3f195eb2bcc044f33
https://doi.org/10.1158/2326-6066.c.6550161.v1
https://doi.org/10.1158/2326-6066.c.6550161.v1
Autor:
Yuan Yuan, Jackson Liang, Daniel Schmolze, Chun-Chieh Chang, Daniel L. Halligan, Paul R. McAdam, Adrian R. Carr, Radia Marie Johnson, Ching-Wei Chang, Susan E. Yost, Katherine E. Hutchinson
Purpose:Emerging data suggest immune checkpoint inhibitors have reduced efficacy in heavily pretreated triple-negative breast cancers (TNBC), but underlying mechanisms are poorly understood. To better understand the phenotypic evolution of TNBCs, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c787f547309f463581297cbc8365dd
https://doi.org/10.1158/1078-0432.c.6528353
https://doi.org/10.1158/1078-0432.c.6528353
Autor:
Yuan Yuan, Jackson Liang, Daniel Schmolze, Chun-Chieh Chang, Daniel L. Halligan, Paul R. McAdam, Adrian R. Carr, Radia Marie Johnson, Ching-Wei Chang, Susan E. Yost, Katherine E. Hutchinson
Correlations between immune gene signature scores and TILs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c92f8997023fc3b5f774575f241f94
https://doi.org/10.1158/1078-0432.22472864
https://doi.org/10.1158/1078-0432.22472864
Autor:
Yuan Yuan, Jackson Liang, Daniel Schmolze, Chun-Chieh Chang, Daniel L. Halligan, Paul R. McAdam, Adrian R. Carr, Radia Marie Johnson, Ching-Wei Chang, Susan E. Yost, Katherine E. Hutchinson
Supplementary Methods, Figure Legends, and References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11b29524ab0778306ea7d0ba8cd04f7
https://doi.org/10.1158/1078-0432.22472861
https://doi.org/10.1158/1078-0432.22472861
Autor:
Yuan Yuan, Radia M. Johnson, Daniel Schmolze, Katherine E. Hutchinson, Adrian R. Carr, Daniel L. Halligan, Ching-Wei Chang, Paul R. McAdam, Susan E. Yost, Jackson Liang, Chun-Chieh Chang
Publikováno v:
Clin Cancer Res
Purpose: Emerging data suggest immune checkpoint inhibitors have reduced efficacy in heavily pretreated triple-negative breast cancers (TNBC), but underlying mechanisms are poorly understood. To better understand the phenotypic evolution of TNBCs, we
Autor:
Joseph Crispell, Roland Harwood, Fraser Menzies, Jimena Guerrero, Paul R. McAdam, Robin A. Skuce, John Lavery, S. Thompson, Pepler Pt, Roman Biek, Andrew W. Byrne, Jordon Graham, Liliana C. M. Salvador, Rowland R. Kao, Trimble N, Wright L, Katarina Oravcova, Eleanor Presho, Adrian R. Allen, Akhmetova A, du Plessis L
Publikováno v:
Microbial Genomics, 9 (5)
Akhmetova, A, Guerrero, J, McAdam, P, Salvador, L C M, Crispell, J, Lavery, J, Presho, E, Kao, R R, Biek, R, Menzies, F, Trimble, N, Harwood, R, Pepler, P T, Oravcova, K, Graham, J, Skuce, R, du Plessis, L, Thompson, S, Wright, L, Byrne, A W & Allen, A R 2023, ' Genomic epidemiology of Mycobacterium bovis infection in sympatric badger and cattle populations in Northern Ireland ', Microbial Genomics, vol. 9, no. 5, pp. 1-17 . https://doi.org/10.1099/mgen.0.001023
Akhmetova, A, Guerrero, J, McAdam, P, Salvador, L C M, Crispell, J, Lavery, J, Presho, E, Kao, R R, Biek, R, Menzies, F, Trimble, N, Harwood, R, Pepler, P T, Oravcova, K, Graham, J, Skuce, R, du Plessis, L, Thompson, S, Wright, L, Byrne, A W & Allen, A R 2023, ' Genomic epidemiology of Mycobacterium bovis infection in sympatric badger and cattle populations in Northern Ireland ', Microbial Genomics, vol. 9, no. 5, pp. 1-17 . https://doi.org/10.1099/mgen.0.001023
Bovine tuberculosis (bTB) is a costly, epidemiologically complex, multi-host, endemic disease. Lack of understanding of transmission dynamics may undermine eradication efforts. Pathogen whole-genome sequencing improves epidemiological inferences, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fb55456a1b0c436155792b486a8804
https://doi.org/10.1101/2021.03.12.435101
https://doi.org/10.1101/2021.03.12.435101