Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Paul R. Langlais"'
Autor:
Hannah R. Ortiz, Paola Cruz Flores, Julia Podgorski, Aaron Ramonett, Tasmia Ahmed, Nadine Hempel, Pascale G. Charest, Nathan A. Ellis, Paul R. Langlais, William R. Montfort, Karthikeyan Mythreye, Sanjay Kumar, Nam Y. Lee
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 53, Iss , Pp 101003- (2024)
Dynamic changes in the endoplasmic reticulum (ER) morphology are central to maintaining cellular homeostasis. Microtubules (MT) facilitate the continuous remodeling of the ER network into sheets and tubules by coordinating with many ER-shaping protei
Externí odkaz:
https://doaj.org/article/274b38172af341548cf9d7362df38b4a
Autor:
Eun‐A. Kwak, Tasmia Ahmed, Paola Cruz Flores, Hannah R. Ortiz, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18981-18987 (2023)
Abstract Background Tumor‐associated angiogenesis mediates the growth and metastasis of most solid cancers. Targeted therapies of the VEGF pathways can effectively block these processes but often fail to provide lasting benefits due to acquired res
Externí odkaz:
https://doaj.org/article/76d3ddb6cc2e43c1a453556387455958
Autor:
Natalie Iannuzo, Holly Welfley, Nicholas C. Li, Michael D. L. Johnson, Joselyn Rojas-Quintero, Francesca Polverino, Stefano Guerra, Xingnan Li, Darren A. Cusanovich, Paul R. Langlais, Julie G. Ledford
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
RationaleCC16 (Club Cell Secretory Protein) is a protein produced by club cells and other non-ciliated epithelial cells within the lungs. CC16 has been shown to protect against the development of obstructive lung diseases and attenuate pulmonary path
Externí odkaz:
https://doaj.org/article/1b7548c5d7bb446b8addfb620c02c69f
Autor:
Rinku S. Skaria, Marissa A. Lopez‐Pier, Brij S. Kathuria, Christian J. Leber, Paul R. Langlais, Shravan G. Aras, Zain I. Khalpey, Pamela G. Hitscherich, Evangelia Chnari, Marc Long, Jared M. Churko, Raymond B. Runyan, John P. Konhilas
Publikováno v:
Physiological Reports, Vol 11, Iss 20, Pp n/a-n/a (2023)
Abstract Cardiac ischemic reperfusion injury (IRI) is paradoxically instigated by reestablishing blood‐flow to ischemic myocardium typically from a myocardial infarction (MI). Although revascularization following MI remains the standard of care, ef
Externí odkaz:
https://doaj.org/article/1914eda30e2946a1b3561fc74669f95e
Autor:
Aidan A. Levine, Erika Liktor-Busa, Shreya Balasubramanian, Seph M. Palomino, Anya M. Burtman, Sarah A. Couture, Austin A. Lipinski, Paul R. Langlais, Tally M. Largent-Milnes
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 531 (2023)
Mounting evidence supports the role of the endocannabinoid system in neurophysiology, including blood–brain barrier (BBB) function. Recent work has demonstrated that activation of endocannabinoid receptors can mitigate insults to the BBB during neu
Externí odkaz:
https://doaj.org/article/8791bae7b6cc4b64bcc65157dedb1cf1
Autor:
Rocio Zapata Bustos, Dawn K. Coletta, Jean-Philippe Galons, Lisa B. Davidson, Paul R. Langlais, Janet L. Funk, Wayne T. Willis, Lawrence J. Mandarino
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Many investigators have attempted to define the molecular nature of changes responsible for insulin resistance in muscle, but a molecular approach may not consider the overall physiological context of muscle. Because the energetic state
Externí odkaz:
https://doaj.org/article/82b20612e80e474a870de114730dd7a4
Publikováno v:
Cells, Vol 12, Iss 15, p 1984 (2023)
Club Cell Secretory Protein (CC16) plays many protective roles within the lung; however, the complete biological functions, especially regarding the pulmonary epithelium during infection, remain undefined. We have previously shown that CC16-deficient
Externí odkaz:
https://doaj.org/article/019ded4da4344feabe7050e405f03af5
Autor:
Eun-A Kwak, Christopher C. Pan, Aaron Ramonett, Sanjay Kumar, Paola Cruz-Flores, Tasmia Ahmed, Hannah R. Ortiz, Jeffrey J. Lochhead, Nathan A. Ellis, Ghassan Mouneimne, Teodora G. Georgieva, Yeon Sun Lee, Todd W. Vanderah, Tally Largent-Milnes, Peter J. Mohler, Thomas J. Hund, Paul R. Langlais, Karthikeyan Mythreye, Nam Y. Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Defective angiogenesis remains a high source of morbidity in multiple disorders. Here they show that βIV-spectrin, a membrane-associated cytoskeletal protein, is essential for regulation of endothelial tip cell populations and VEGF signaling during
Externí odkaz:
https://doaj.org/article/9b6fe5a83d2b46eeafef20d5197ddbd4
Autor:
Alane Blythe C. Dy, Paul R. Langlais, Natalie K. Barker, Kenneth J. Addison, Sasipa Tanyaratsrisakul, Scott Boitano, Stephanie A. Christenson, Monica Kraft, Deborah Meyers, Eugene R. Bleecker, Xingnan Li, Julie G. Ledford
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Surfactant protein A (SP-A) is well-known for its protective role in pulmonary immunity. Previous studies from our group have shown that SP-A mediates eosinophil activities, including degranulation and apoptosis. In order to identify potenti
Externí odkaz:
https://doaj.org/article/244289d7afde4e5da5b059c96da2f77b
Autor:
Aidan Levine, Erika Liktor-Busa, Austin A. Lipinski, Sarah Couture, Shreya Balasubramanian, Sue A. Aicher, Paul R. Langlais, Todd W. Vanderah, Tally M. Largent-Milnes
Publikováno v:
Biology of Sex Differences, Vol 12, Iss 1, Pp 1-18 (2021)
Abstract Background Several chronic pain disorders, such as migraine and fibromyalgia, have an increased prevalence in the female population. The underlying mechanisms of this sex-biased prevalence have yet to be thoroughly documented, but could be r
Externí odkaz:
https://doaj.org/article/e0214959706c44d694e36094c2dc740a