Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Paul R. Knight"'
Autor:
Siavash Sedghi, Wiam Z. Khadra, Leili Pourafkari, Paul R. Knight, Faraz A. Alderson, Nader D. Nader
Publikováno v:
Journal of Cardiovascular and Thoracic Research, Vol 15, Iss 3, Pp 138-144 (2023)
Introduction: Volatile anesthetics offer protection when administered throughout an ischemic injury. We examined how volatile anesthetics modulate the cardiac myocytic injury associated with hydrogen peroxide. Methods: Forty-eight Long-Evans rats wer
Externí odkaz:
https://doaj.org/article/e643df1134994b23827fa55b4a60f7a5
Autor:
Neetu Singh, Priya Ranjan, Weiping Cao, Jenish Patel, Shivaprakash Gangappa, Bruce A. Davidson, John M. Sullivan, Paras N. Prasad, Paul R. Knight, Suryaprakash Sambhara
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss , Pp 1413-1422 (2020)
Retinoic acid-inducible gene-I (RIG-I) is a cytosolic pathogen sensor that is crucial against a number of viral infections. Many viruses have evolved to inhibit pathogen sensors to suppress host innate immune responses. In the case of influenza, nons
Externí odkaz:
https://doaj.org/article/0962e1e755b24d7cbac0bd139f553d07
Autor:
Nader D. Nader, Mehrdad Asgeri, Sina Davari-Farid, Leili Pourafkari, Faraz Ahmadpour, Jahan Porhomayon, Hassan Javadzadeghan, Sohrab Negargar, Paul R. Knight III
Publikováno v:
Journal of Cardiovascular and Thoracic Research, Vol 7, Iss 3, Pp 81-86 (2015)
Introduction: Myocardial ischemia may coincide and interact with sepsis and inflammation. Our objective was to examine the effects of bacterial endotoxin on myocardial functions and cell injury during acute ischemia. Methods: Rabbits were pretreated
Externí odkaz:
https://doaj.org/article/89597b9f14c84d51badf01da7a7ebb87
Publikováno v:
mBio, Vol 4, Iss 4 (2013)
ABSTRACT Streptococcus pneumoniae is a common human nasopharyngeal commensal colonizing 10% to 40% of healthy individuals, depending on age. Despite a low invasive disease rate, widespread carriage ensures that infection occurs often enough to make S
Externí odkaz:
https://doaj.org/article/fae1ba4b5154420583c0e91c64ac97ab
Autor:
Rashmi Kumari, Suresh D. Sharma, Amrita Kumar, Zachary Ende, Margarita Mishina, Yuanyuan Wang, Zackary Falls, Ram Samudrala, Jan Pohl, Paul R. Knight, Suryaprakash Sambhara
Publikováno v:
Clinical Microbiology Reviews. 36
Preventing and controlling influenza virus infection remains a global public health challenge, as it causes seasonal epidemics to unexpected pandemics. These infections are responsible for high morbidity, mortality, and substantial economic impact.
Autor:
Paul R. Knight, Bruce A. Davidson, Suryaprakash Sambhara, Priya Ranjan, Weiping Cao, Jack M. Sullivan, Neetu Singh, Shivaprakash Gangappa, Paras N. Prasad, Jenish R. Patel
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss, Pp 1413-1422 (2020)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Retinoic acid-inducible gene-I (RIG-I) is a cytosolic pathogen sensor that is crucial against a number of viral infections. Many viruses have evolved to inhibit pathogen sensors to suppress host innate immune responses. In the case of influenza, nons
Autor:
Suryaprakash Sambhara, Jonathan F. Lovell, Blaine A. Pfeifer, Wadzanai P Mboko, Margarita Mishina, Caitlin Bohannon, Bruce A. Davidson, Suresh K. Mittal, Priya Ranjan, Amrita Kumar, Weiping Cao, Paul R. Knight, Samuel Amoah, Shivaprakash Gangappa, Adolfo García-Sastre, Zachary Ende
Publikováno v:
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Advanced Science
Advanced Science
Influenza infections cause several million cases of severe respiratory illness, hospitalizations, and hundreds of thousands of deaths globally. Secondary infections are a leading cause of influenza's high morbidity and mortality, and significantly fa
Publikováno v:
Immunological Investigations. 46:793-804
Historically, volatile anesthetics have demonstrated interesting interactions with both the innate and adaptive immune systems. This review organizes these interactions into four phases: recognition, recruitment, response, and resolution. These phase
Autor:
Jahan Porhomayon, Leili Pourafkari, Paul R. Knight, Sina Davari-Farid, Hassan Javadzadeghan, Nader D. Nader, Sohrab Negargar, Mehrdad Asgeri, Faraz Ahmadpour
Publikováno v:
Journal of Cardiovascular and Thoracic Research, Vol 7, Iss 3, Pp 81-86 (2015)
Journal of Cardiovascular and Thoracic Research
Journal of Cardiovascular and Thoracic Research
Introduction: Myocardial ischemia may coincide and interact with sepsis and inflammation. Our objective was to examine the effects of bacterial endotoxin on myocardial functions and cell injury during acute ischemia. Methods: Rabbits were pretreated
Autor:
Guojian Zhang, Paul R. Knight, Pooya Rostami, Yi Li, Andrew Hill, Charles H. Jones, Bruce A. Davidson, Blaine A. Pfeifer, Marie Beitelshees, Roozbeh Nayerhoda
Publikováno v:
Science Advances
A comprehensive design offers global pneumococcal vaccine coverage.
Commensal organisms with the potential to cause disease pose a challenge in developing treatment options. Using the example featured in this study, pneumococcal disease begins w
Commensal organisms with the potential to cause disease pose a challenge in developing treatment options. Using the example featured in this study, pneumococcal disease begins w