Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Paul R. Jamieson"'
Autor:
Anne C. Rios, Nai Yang Fu, Paul R. Jamieson, Bhupinder Pal, Lachlan Whitehead, Kevin R. Nicholas, Geoffrey J. Lindeman, Jane E. Visvader
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The main function of the mammary gland is to produce milk to sustain offspring. Here, the authors show that secretory alveolar cells in the lactating gland in several species are binucleated, which increases milk production, and that binucleation is
Externí odkaz:
https://doaj.org/article/b9df98d6e85146f8b1f32303442dfa3f
Autor:
Courtney L.R. Jurd, Kathleen S. Ensbey, Thomas Robertson, Zara C. Bruce, Paul R. Jamieson, Carolin Offenhäuser, Rochelle C.J. D’Souza, Bryan W. Day, Fiona M. Smith, Andrew W. Boyd, Po Inglis, Rosalind L. Jeffree, Kevin P. Campbell, Seckin Akgul, Yuchen Li, Justin D. Lathia, Zarnie Lwin, Yi Chieh Lim, Jeremy N. Rich, Terrance Grant Johns, Brett W. Stringer, Krishna P.L. Bhat, Ulrich Baumgartner
Publikováno v:
Acta Neuropathologica
Glioblastomas (GBMs) are malignant central nervous system (CNS) neoplasms with a very poor prognosis. They display cellular hierarchies containing self-renewing tumourigenic glioma stem cells (GSCs) in a complex heterogeneous microenvironment. One pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4cca91aff1af90b0d448638734a9e31
http://europepmc.org/articles/PMC6851226
http://europepmc.org/articles/PMC6851226
Autor:
Huili Hu, Ellen J. Wehrens, Koen C. Oost, Anne C. Rios, Annelotte M. Vonk, Jane E. Visvader, Hans Clevers, Johanna F. Dekkers, Paul R. Jamieson, Hendrikus C R Ariese, Maria Alieva, Jeffrey M. Beekman, Hugo J. Snippert, Gimano D. Amatngalim, Lianne M Wellens
Publikováno v:
Nature Protocols, 14(6), 1756-1771. Nature Publishing Group
In vitro 3D organoid systems have revolutionized the modeling of organ development and diseases in a dish. Fluorescence microscopy has contributed to the characterization of the cellular composition of organoids and demonstrated organoids' phenotypic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e167f6e747cde0439071404446ac4798
https://doi.org/10.1038/s41596-019-0160-8
https://doi.org/10.1038/s41596-019-0160-8
Autor:
Suzanne Allan, Rochelle C.J. D’Souza, S. Campbell, Hongdo Do, Kate Goasdoué, Peter Lucas, Alexander Dobrovic, Po Inglis, Zara C. Bruce, Gert Tollesson, Craig Winter, Andrew W. Boyd, Paul R. Jamieson, Carolin Offenhäuser, Rosalind L. Jeffree, Bryan W. Day, Seckin Akgul, Kathleen S. Ensbey, Brett W. Stringer, Thomas Robertson, Terrance Grant Johns, Yi Chieh Lim
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Low-passage, serum-free cell lines cultured from patient tumour tissue are the gold-standard for preclinical studies and cellular investigations of glioblastoma (GBM) biology, yet entrenched, poorly-representative cell line models are still widely us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7e5b4cea2e609465eaf940fffdf522
http://link.springer.com/article/10.1038/s41598-019-41277-z
http://link.springer.com/article/10.1038/s41598-019-41277-z
Autor:
François Vaillant, Jane E. Visvader, Matthew E. Ritchie, Felicity C. Jackling, Nai Yang Fu, Bhupinder Pal, Gordon K. Smyth, Paul R. Jamieson, Ruijie Liu, Charity W. Law, Anne C. Rios, Geoffrey J. Lindeman, Kevin H. Liu
Publikováno v:
Nature Cell Biology. 19:164-176
Despite accumulating evidence for a mammary differentiation hierarchy, the basal compartment comprising stem cells remains poorly characterized. Through gene expression profiling of Lgr5+ basal epithelial cells, we identify a new marker, Tetraspanin8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61e14343241d8fb7e13277009c4d08c
https://doi.org/10.1038/ncb3471
https://doi.org/10.1038/ncb3471
Autor:
Terrance Grant Johns, Zara C. Bruce, Jeremy N. Rich, Krishna Bhat, Kevin P. Campbell, Justin D. Lathia, Yi Chieh Lim, Ulrich Baumgartner, Kathleen S. Ensbey, Fiona M. Smith, Brett W. Stringer, Paul R. Jamieson, Carolin Offenhäuser, Courtney L.R. Jurd, Thomas Robertson, Bryan W. Day, Rochelle C.J. D’Souza, Andrew W. Boyd, Rosalind L. Jeffree, Seckin Akgul, Yuchen Li
Publikováno v:
Neuro Oncol
Glioblastomas (GBMs) are malignant central nervous system (CNS) neoplasms with a very poor prognosis. They display cellular hierarchies containing self-renewing tumourigenic glioma stem cells (GSCs) in a complex heterogeneous microenvironment. One pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d84697f3ebedd4d0713fced4bccef21
https://europepmc.org/articles/PMC6846012/
https://europepmc.org/articles/PMC6846012/
Autor:
Johanna F, Dekkers, Maria, Alieva, Lianne M, Wellens, Hendrikus C R, Ariese, Paul R, Jamieson, Annelotte M, Vonk, Gimano D, Amatngalim, Huili, Hu, Koen C, Oost, Hugo J G, Snippert, Jeffrey M, Beekman, Ellen J, Wehrens, Jane E, Visvader, Hans, Clevers, Anne C, Rios
Publikováno v:
Nature protocols. 14(6)
In vitro 3D organoid systems have revolutionized the modeling of organ development and diseases in a dish. Fluorescence microscopy has contributed to the characterization of the cellular composition of organoids and demonstrated organoids' phenotypic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfeb8b343ff23dcd68671deb3088f4bb
https://pubmed.ncbi.nlm.nih.gov/31053799
https://pubmed.ncbi.nlm.nih.gov/31053799
Autor:
Kate Goasdoué, Sara Charmsaz, Guy Barry, Fiona M. Smith, Leanne Cooper, Hélène Vidal, Andrew W. Boyd, Michael Piper, Zara C. Bruce, Jens Bunt, Paul R. Jamieson, Brett W. Stringer, Linda J. Richards, Kathleen S. Ensbey, Bryan W. Day
Publikováno v:
Oncotarget
Glioblastoma (GBM) is an essentially incurable and rapidly fatal cancer, with few markers predicting a favourable prognosis. Here we report that the transcription factor NFIB is associated with significantly improved survival in GBM. NFIB expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b971149dc5a70d4f6ffea6fa3777918c
https://doi.org/10.18632/oncotarget.8720
https://doi.org/10.18632/oncotarget.8720
Autor:
Peter Lucas, Zara C. Bruce, Bryan W. Day, Kate Goasdoué, S. Campbell, Terrance Grant Johns, Alexander Dobrovic, Thomas Robertson, Gert Tollesson, Craig Winter, Rochelle C.J. D’Souza, Rosalind L. Jeffree, Yi Chieh Lim, Po-Ling Inglis, Seckin Akgul, Brett W. Stringer, Andrew W. Boyd, Suzanne Allan, Hongdo Do, Kathleen S. Ensbey, Paul R. Jamieson, Carolin Offenhäuser
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d69d44f72ad1796d6049c168ca7d9ee
http://link.springer.com/article/10.1038/s41598-020-57850-w
http://link.springer.com/article/10.1038/s41598-020-57850-w
Autor:
Zara C. Bruce, Stephen E. Rose, Simon Puttick, Paul R. Jamieson, Carolin Offenhäuser, Brett W. Stringer, Rosalind L. Jeffree, Craig A. Bell, Benjamin Carrington, Kathleen S. Ensbey, Adrian V. Fuchs, Andrew W. Boyd, Kristofer J. Thurecht, Bryan W. Day, Fares Al-Ejeh, Fiona M. Smith
Publikováno v:
Cancers
Cancers, Vol 10, Iss 12, p 519 (2018)
Volume 10
Issue 12
Cancers, Vol 10, Iss 12, p 519 (2018)
Volume 10
Issue 12
The EphA3 receptor has recently emerged as a functional tumour-specific therapeutic target in glioblastoma (GBM). EphA3 is significantly elevated in recurrent disease, is most highly expressed on glioma stem cells (GSCs), and has a functional role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b357de6bcf6c1d31962f06916153f9
https://pubmed.ncbi.nlm.nih.gov/30562956
https://pubmed.ncbi.nlm.nih.gov/30562956