Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Paul R. Gater"'
Publikováno v:
The Journal of Immunology. 166:1233-1240
Ag-specific activation of CD4+ T cells is known to be causative for the cytokine production associated with lung allergy. Chemokine-induced leukocyte recruitment potentially represents a critical early event in Ag-induced lung inflammation. Whether A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73dd61f3966b79c8f252569034345af
https://doi.org/10.4049/jimmunol.166.2.1233
https://doi.org/10.4049/jimmunol.166.2.1233
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 161:1340-1348
CD4(+) T cells are thought to play a major role in the initiation and perpetuation of T helper cell, type 2 (Th2)-like allergic airway inflammation. However, it is not clear whether activation of resident antigen-specific CD4(+) T cells is in itself
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81366050e34457a659300d4a4ebd6bf7
https://doi.org/10.1164/ajrccm.161.4.9906078
https://doi.org/10.1164/ajrccm.161.4.9906078
Publikováno v:
European Journal of Pharmacology. 304:123-128
Endothelin exerts a variety of biological effects in the lung which indicate that this peptide may have a role in the pathophysiology of a number of pulmonary diseases. In this study, the endothelin receptors on the human bronchus were compared with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a2e080d72a3e05e12dbfa85a4535fc
https://doi.org/10.1016/0014-2999(96)00125-2
https://doi.org/10.1016/0014-2999(96)00125-2
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 14:454-460
Tumor necrosis factor (TNF) is an inflammatory cytokine produced by many cell types which may contribute to the pathophysiology of a variety of lung diseases. In this study we have used Ro 45-2081 (a soluble receptor composed of the human p55 TNF rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498f860312671a82bc6d896236f1d710
https://doi.org/10.1165/ajrcmb.14.5.8624250
https://doi.org/10.1165/ajrcmb.14.5.8624250
Autor:
Michael Brewster, Peter M. Paciorek, John F. Waterfall, Jennifer C. McKean, Kevin L. Wilson, Paul R. Gater
Publikováno v:
European Journal of Pharmacology. 238:59-64
This study compares the effects of two K(+0-channel openers, Ro 31-6930 and BRL 38227, on cholinergically-evoked contraction of guinea-pig airways to examine whether either compound acts through prejunctional inhibition of the release of acetylcholin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa708d4bb12b5d70529b3bbdaf5b42da
https://doi.org/10.1016/0014-2999(93)90505-c
https://doi.org/10.1016/0014-2999(93)90505-c
Autor:
Fabien Schmidlin, Patrick G. Knott, David Lewis, Paul R. Gater, Silvia Amadesi, Karim Dabbagh, Pierangelo Geppetti, Claude Bertrand, Nigel W. Bunnett, Mary E. Stevens
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 169(9)
Trypsin and mast cell tryptase can signal to epithelial cells, myocytes, and nerve fibers of the respiratory tract by cleaving proteinase-activated receptor 2 (PAR2). Since tryptase inhibitors are under development to treat asthma, a precise understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e2c3b73cca6bac0b5ce3ad11b8d04c
https://pubmed.ncbi.nlm.nih.gov/12391252
https://pubmed.ncbi.nlm.nih.gov/12391252