Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Paul R Sanders"'
Autor:
Hayley E. Bullen, Paul R. Sanders, Madeline G. Dans, Thorey K. Jonsdottir, David T. Riglar, Oliver Looker, Catherine S. Palmer, Betty Kouskousis, Sarah C. Charnaud, Tony Triglia, Mikha Gabriela, Molly Parkyn Schneider, Jo‐Anne Chan, Tania F. de Koning‐Ward, Jake Baum, James W. Kazura, James G. Beeson, Alan F. Cowman, Paul R. Gilson, Brendan S. Crabb
Publikováno v:
Molecular Microbiology. 117:1245-1262
Infection with Plasmodium falciparum parasites results in approximately 627,000 deaths from malaria annually. Key to the parasite's success is their ability to invade and subsequently grow within human erythrocytes. Parasite proteins involved in para
Autor:
Natalie A Counihan, Scott A Chisholm, Hayley E Bullen, Anubhav Srivastava, Paul R Sanders, Thorey K Jonsdottir, Greta E Weiss, Sreejoyee Ghosh, Brendan S Crabb, Darren J Creek, Paul R Gilson, Tania F de Koning-Ward
Publikováno v:
eLife, Vol 6 (2017)
Plasmodium falciparum parasites, the causative agents of malaria, modify their host erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and for removal of toxic waste. Here we investigate the contribution of the rhop
Externí odkaz:
https://doaj.org/article/97ed3bf0078b4d8eba8c42a7a6284862
Autor:
Sarah C Charnaud, Matthew W A Dixon, Catherine Q Nie, Lia Chappell, Paul R Sanders, Thomas Nebl, Eric Hanssen, Matthew Berriman, Jo-Anne Chan, Adam J Blanch, James G Beeson, Julian C Rayner, Jude M Przyborski, Leann Tilley, Brendan S Crabb, Paul R Gilson
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181656 (2017)
Malaria is caused by five different Plasmodium spp. in humans each of which modifies the host erythrocyte to survive and replicate. The two main causes of malaria, P. falciparum and P. vivax, differ in their ability to cause severe disease, mainly du
Externí odkaz:
https://doaj.org/article/9c7a23a7856f435780cc653721a9fc78
Autor:
Khayriyyah Mohd Hanafiah, Norsyahida Arifin, Paul R. Sanders, Nurulhasanah Othman, Mary L. Garcia, David A. Anderson
Publikováno v:
Vaccines, Vol 7, Iss 3, p 80 (2019)
Tuberculosis (TB) is ranked among the top 10 causes of death worldwide. New biomarker-based serodiagnostics and vaccines are unmet needs stalling disease control. Antigen 60 (A60) is a thermostable mycobacterial complex typically purified from Bacill
Externí odkaz:
https://doaj.org/article/cf62994051e34924b836aec10569da42
Autor:
Paul R Sanders, Betty Kouskousis, Thorey K Jonsdottir, Hayley E Bullen, Paul R. Gilson, Natalie A. Counihan, Brendan S. Crabb, Mikha Gabriela, Tania F. de Koning-Ward, Joyanta K Modak
Publikováno v:
Cellular Microbiology
During its intraerythrocytic life cycle, the human malaria parasite Plasmodium falciparum supplements its nutritional requirements by scavenging substrates from the plasma through the new permeability pathways (NPPs) installed in the red blood cell (
Autor:
Mauro F Azevedo, Catherine Q Nie, Brendan Elsworth, Sarah C Charnaud, Paul R Sanders, Brendan S Crabb, Paul R Gilson
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112571 (2014)
Drug discovery is a key part of malaria control and eradication strategies, and could benefit from sensitive and affordable assays to quantify parasite growth and to help identify the targets of potential anti-malarial compounds. Bioluminescence, ach
Externí odkaz:
https://doaj.org/article/e22dc4da0f204f41a369e9e8435d12dc
Autor:
Tana Taechalertpaisarn, Cecile Crosnier, S Josefin Bartholdson, Anthony N Hodder, Jenny Thompson, Leyla Y Bustamante, Danny W Wilson, Paul R Sanders, Gavin J Wright, Julian C Rayner, Alan F Cowman, Paul R Gilson, Brendan S Crabb
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41937 (2012)
The genomes of Plasmodium parasites that cause malaria in humans, other primates, birds, and rodents all encode multiple 6-cys proteins. Distinct 6-cys protein family members reside on the surface at each extracellular life cycle stage and those on t
Externí odkaz:
https://doaj.org/article/dca07fcb739f49178ad52a9708af4d0e
Autor:
Damien R. Drew, Brendan S. Crabb, Gretchen Weiss, Paul R. Gilson, James G. Beeson, Paul R Sanders
Publikováno v:
The Journal of Infectious Diseases. 217:498-507
Plasmodium vivax and P. falciparum malaria species have diverged significantly in receptor-ligand interactions and host-cell invasion. One protein common to both is the merozoite invasion ligand AMA1. While the general structure of AMA1 is similar be
Autor:
Mary L Garcia, Paul R Sanders, Norsyahida Arifin, Nurulhasanah Othman, David A. Anderson, Khayriyyah Mohd Hanafiah
Publikováno v:
Vaccines, Vol 7, Iss 3, p 80 (2019)
Vaccines
Volume 7
Issue 3
Vaccines
Volume 7
Issue 3
Tuberculosis (TB) is ranked among the top 10 causes of death worldwide. New biomarker-based serodiagnostics and vaccines are unmet needs stalling disease control. Antigen 60 (A60) is a thermostable mycobacterial complex typically purified from Bacill
Autor:
Brendan S. Crabb, Brendan Elsworth, Paul R Sanders, Sarah C. Charnaud, Leann Tilley, Steven Batinovic, Thomas Nebl, Catherine Q Nie, Ming Kalanon, Hayley E Bullen, Tania F. de Koning Ward, Paul R. Gilson
Publikováno v:
Cellular Microbiology. 18:1551-1569
The Plasmodium translocon for exported proteins (PTEX) has been established as the machinery responsible for the translocation of all classes of exported proteins beyond the parasitophorous vacuolar membrane of the intraerythrocytic malaria parasite.