Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Paul R Riley"'
Autor:
Daniyal J Jafree, Dale Moulding, Maria Kolatsi-Joannou, Nuria Perretta Tejedor, Karen L Price, Natalie J Milmoe, Claire L Walsh, Rosa Maria Correra, Paul JD Winyard, Peter C Harris, Christiana Ruhrberg, Simon Walker-Samuel, Paul R Riley, Adrian S Woolf, Peter J Scambler, David A Long
Publikováno v:
eLife, Vol 8 (2019)
Heterogeneity of lymphatic vessels during embryogenesis is critical for organ-specific lymphatic function. Little is known about lymphatics in the developing kidney, despite their established roles in pathology of the mature organ. We performed three
Externí odkaz:
https://doaj.org/article/19f52d73e1eb45febdf317aa6d8af0b5
Autor:
Richard CV Tyser, Antonio MA Miranda, Chiann-mun Chen, Sean M Davidson, Shankar Srinivas, Paul R Riley
Publikováno v:
eLife, Vol 5 (2016)
The mammalian heartbeat is thought to begin just prior to the linear heart tube stage of development. How the initial contractions are established and the downstream consequences of the earliest contractile function on cardiac differentiation and mor
Externí odkaz:
https://doaj.org/article/7b0318b9436e4a8fb4d03847c3efd7d4
Autor:
William J. Mason, Daniyal J. Jafree, Gideon Pomeranz, Maria Kolatsi-Joannou, Antje K. Rottner, Sabrina Pacheco, Dale A. Moulding, Anja Wolf, Christian Kupatt, Claire Peppiatt-Wildman, Eugenia Papakrivopoulou, Paul R. Riley, David A. Long, Elisavet Vasilopoulou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Plasma ultrafiltration in the kidney occurs across glomerular capillaries, which are surrounded by epithelial cells called podocytes. Podocytes have a unique shape maintained by a complex cytoskeleton, which becomes disrupted in glomerular d
Externí odkaz:
https://doaj.org/article/37e6c94bbdf24a1381837add4474bfb3
Autor:
Vanessa Chong-Morrison, Sarah Mayes, Filipa C. Simões, Upeka Senanayake, Dervla S. Carroll, Paul R. Riley, Stephen W. Wilson, Tatjana Sauka-Spengler
Publikováno v:
Biology Open, Vol 12, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/c739f6aea577440f95f5e751d78dcafe
Autor:
Jacinta I. Kalisch-Smith, Emily C. Morris, Mary A. A. Strevens, Andia N. Redpath, Kostantinos Klaourakis, Dorota Szumska, Jennifer E. Outhwaite, Xin Sun, Joaquim Miguel Vieira, Nicola Smart, Sarah De Val, Paul R. Riley, Duncan B. Sparrow
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
The placental vasculature provides the developing embryo with a circulation to deliver nutrients and dispose of waste products. However, in the mouse, the vascular components of the chorio-allantoic placenta have been largely unexplored due to a lack
Externí odkaz:
https://doaj.org/article/65a5a2d0d0f643d38839c84a26d650f5
Autor:
Filipa C. Simões, Thomas J. Cahill, Amy Kenyon, Daria Gavriouchkina, Joaquim M. Vieira, Xin Sun, Daniela Pezzolla, Christophe Ravaud, Eva Masmanian, Michael Weinberger, Sarah Mayes, Madeleine E. Lemieux, Damien N. Barnette, Mala Gunadasa-Rohling, Ruth M. Williams, David R. Greaves, Le A. Trinh, Scott E. Fraser, Sarah L. Dallas, Robin P. Choudhury, Tatjana Sauka-Spengler, Paul R. Riley
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Macrophages mediate the fibrotic response after a heart attack by extracellular matrix turnover and cardiac fibroblasts activation. Here the authors identify an evolutionarily-conserved function of macrophages that contributes directly to the forming
Externí odkaz:
https://doaj.org/article/edf55153a7b34a528c084339f4ceeac3
Autor:
Carla De Villiers, Paul R. Riley
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 11 (2020)
Myocardial infarction (MI) is a disease of major consequence in the modern world, causing permanent, irreversible damage to the heart. Survivors are at risk for developing further cardiovascular pathologies such as heart failure. Further study of MI
Externí odkaz:
https://doaj.org/article/388bfcc5855b4c86be56049815e70e86
Publikováno v:
Cells, Vol 10, Iss 10, p 2594 (2021)
Recent advances in our understanding of the lymphatic system, its function, development, and role in pathophysiology have changed our views on its importance. Historically thought to be solely involved in the transport of tissue fluid, lipids, and im
Externí odkaz:
https://doaj.org/article/0ea3561c97004382a0312b9be3cd85d0
Autor:
Joaquim Miguel Vieira, Sara Howard, Cristina Villa del Campo, Sveva Bollini, Karina N. Dubé, Megan Masters, Damien N. Barnette, Mala Rohling, Xin Sun, Laura E. Hankins, Daria Gavriouchkina, Ruth Williams, Daniel Metzger, Pierre Chambon, Tatjana Sauka-Spengler, Benjamin Davies, Paul R. Riley
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Priming of the adult mouse heart with Tβ4 activates dormant epicardium-derived cells to aid repair of injured myocardium. Here, Vieiraet al. explain this process and show that Tβ4 binds a chromatin remodeller BRG1 and activates Wt1, the key regulat
Externí odkaz:
https://doaj.org/article/016d532aec994a92bc77e854190df861
Autor:
Jana Koth, Mahon L. Maguire, Darryl McClymont, Leonie Diffley, Victoria L. Thornton, John Beech, Roger K. Patient, Paul R. Riley, Jürgen E. Schneider
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The adult zebrafish is a well-established model for studying heart regeneration, but due to its tissue opaqueness, repair has been primarily assessed using destructive histology, precluding repeated investigations of the same animal. We pres
Externí odkaz:
https://doaj.org/article/df3a001c45664798981cda1674ac34b4