Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Paul R Hess"'
Autor:
Ellen M Leitman, Christine D Palmer, Søren Buus, Fabian Chen, Lynn Riddell, Stuart Sims, Paul Klenerman, Asier Sáez-Cirión, Bruce D Walker, Paul R Hess, Marcus Altfeld, Philippa C Matthews, Philip J R Goulder
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0184496 (2017)
Antigen-specific T-cells are highly variable, spanning potent antiviral efficacy and damaging auto-reactivity. In virus infections, identifying the most efficacious responses is critical to vaccine design. However, current methods depend on indirect
Externí odkaz:
https://doaj.org/article/fb7a3d6217b74a1fa025d6dc51b45b58
Autor:
Kaishu Mason, Anuja Sathe, Paul R. Hess, Jiazhen Rong, Chi-Yun Wu, Emma Furth, Katalin Susztak, Jonathan Levinsohn, Hanlee P. Ji, Nancy Zhang
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-33 (2024)
Abstract Existing methods for analysis of spatial transcriptomic data focus on delineating the global gene expression variations of cell types across the tissue, rather than local gene expression changes driven by cell-cell interactions. We propose a
Externí odkaz:
https://doaj.org/article/584d5b43dfac4a9b8622ba36a4824e07
Autor:
Giichi Takaesu, Maiko Inagaki, Keiyo Takubo, Yuji Mishina, Paul R Hess, Gregg A Dean, Akihiko Yoshimura, Kunihiro Matsumoto, Toshio Suda, Jun Ninomiya-Tsuji
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e51073 (2012)
A cytokine/stress signaling kinase Tak1 (Map3k7) deficiency is known to impair hematopoietic progenitor cells. However, the role of TAK1 signaling in the stem cell function of the hematopoietic system is not yet well defined. Here we characterized he
Externí odkaz:
https://doaj.org/article/6b707aa788c14c03ae9c4216e9ae859f
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105996- (2023)
Summary: The major histocompatibility complex class I (MHC-I) genes are highly polymorphic. MHC-I genotyping is required for determining the peptide epitopes available to an individual’s T-cell repertoire. Current genotyping software tools do not w
Externí odkaz:
https://doaj.org/article/3e4c53e219604121b1b4cececa4035cd
Publikováno v:
Journal of the American Veterinary Medical Association. :1-7
OBJECTIVE To evaluate the efficacy of doxorubicin for treatment of histiocytic sarcoma (HS) in dogs, whether administered as the sole treatment or as an adjunct to surgery or radiation therapy. ANIMALS 31 client-owned dogs with localized or dissemina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90837db7d92474cb36453516778d39f
https://doi.org/10.2460/javma.21.11.0498
https://doi.org/10.2460/javma.21.11.0498
Autor:
Paul R. Hess
Publikováno v:
Schalm's Veterinary Hematology. :48-62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4368006010095288276e20cc062fcf57
https://doi.org/10.1002/9781119500537.ch7
https://doi.org/10.1002/9781119500537.ch7
Publikováno v:
Immunogenetics. 73:381-393
Of the 12 full-length feline leukocyte antigen class I (FLAI) loci, 3 are presumed to be classical: FLAI-E, FLAI-H, and FLAI-K. As diversity is a class Ia hallmark, multi-allelism is an important surrogate supporting a classical designation, in the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab2fc1396ea88fe8f08f64a07e0b1075
https://doi.org/10.1007/s00251-021-01221-w
https://doi.org/10.1007/s00251-021-01221-w
Autor:
Chi-Yun Wu, Anuja Sathe, Jiazhen Rong, Paul R. Hess, Billy T. Lau, Susan M. Grimes, Hanlee P. Ji, Nancy R. Zhang
In cancer, somatic mutations such as copy number alterations (CNAs) accumulate during disease progression and lead to functional intra-tumor heterogeneity that can influence the efficacy of cancer therapy. Therefore, studying the functional character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d165844e3968d757d296b559bf66819
https://doi.org/10.1101/2022.07.05.498882
https://doi.org/10.1101/2022.07.05.498882
Publikováno v:
HLA. 97:428-434
Canine spontaneous cancers may offer greater fidelity than rodent models in advancing clinical immunotherapies. Boxers in particular are distinguished as study subjects by their popularity, and high incidence of human-relevant cancers. Further, the M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5263f2b99ec003d2883c4d2a929497
https://doi.org/10.1111/tan.14197
https://doi.org/10.1111/tan.14197
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e11caa639a6c36fbaf766672934c28d
https://doi.org/10.2139/ssrn.4179763
https://doi.org/10.2139/ssrn.4179763