Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Paul R Fallen"'
Themis controls thymocyte selection through regulation of T cell antigen receptor–mediated signaling
Autor:
Guo Fu, Oreste Acuto, Jianfang Hu, Anil Munshi, Vasily Rybakin, Sébastien Vallée, Marielena V. McGuire, Claudia Brockmeyer, Mogjiborahman Salek, John A. H. Hoerter, Nicholas R. J. Gascoigne, Howard S Fox, Karsten Sauer, Yina H. Huang, Jeanette Ampudia, Paul R Fallen
Publikováno v:
Nature immunology
Themis (thymocyte-expressed molecule involved in selection), a member of a family of proteins with unknown functions, is highly conserved among vertebrates. Here we found that Themis had high expression in thymocytes between the pre-T cell antigen re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a2c5923d15a9f2bdd67bd592a4251d
https://doi.org/10.1038/ni.1766
https://doi.org/10.1038/ni.1766
Publikováno v:
Immunology Letters. 75:85-88
We wanted to determine whether naive T cells could make the Types 1, 2 and 0 defining cytokines Interleukin (IL)-4 and Interferon (IFN)gamma. We show that stimulation of naive T cells (CD3+ CD45RA+) derived from cord blood by phorbol ester (phorbol-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a86dab68dcf9eba985e97ffc6a4c05
https://doi.org/10.1016/s0165-2478(00)00279-0
https://doi.org/10.1016/s0165-2478(00)00279-0
Publikováno v:
Human Immunology. 60:331-336
To date, over 400 human umbilical cord blood cord blood (CB) transplants have been reported from different centres world-wide and it is generally agreed that CB represents an encouraging alternative to bone marrow (BM) transplantation. There are a va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bac1a1ba6d5c30a97171f974dea7c30
https://doi.org/10.1016/s0198-8859(98)00126-8
https://doi.org/10.1016/s0198-8859(98)00126-8
Autor:
Maria Alcocer, Katarzyna Bogunia-Kubik, Joanna Wolley, Prasad Natarajan, Sarah Brown, Paul R Fallen, S. B. A. Cohen, J. Alejandro Madrigal
Publikováno v:
Cytokine. 22(1-2)
The current literature suggests that cord blood (CB) cells are functionally immature. We previously reported that CB sera inhibit T cell proliferation and suggested that the microenvironment in which CB T cells reside may be, in part, responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa1f6bea630eb5e8f2f28301d635802
https://pubmed.ncbi.nlm.nih.gov/12946104
https://pubmed.ncbi.nlm.nih.gov/12946104
Autor:
Katarzyna Bogunia-Kubik, S. B. A. Cohen, J. Alejandro Madrigal, Paul R Fallen, Isabel Perez-Cruz
Publikováno v:
Immunology letters. 72(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9982051297f7c2ea406b3f36679cea
https://pubmed.ncbi.nlm.nih.gov/10950642
https://pubmed.ncbi.nlm.nih.gov/10950642