Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Paul R Burton"'
Autor:
Madeleine J. Murtagh, Joel T. Minion, Andrew Turner, Rebecca C. Wilson, Mwenza Blell, Cynthia Ochieng, Barnaby Murtagh, Stephanie Roberts, Oliver W. Butters, Paul R Burton
Publikováno v:
BMC Medical Ethics, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Because no single person or group holds knowledge about all aspects of research, mechanisms are needed to support knowledge exchange and engagement. Expertise in the research setting necessarily includes scientific and methodologi
Externí odkaz:
https://doaj.org/article/b842879399314703b3284e76bd7abc47
Autor:
Ma'en Obeidat, Louise V Wain, Nick Shrine, Noor Kalsheker, Maria Soler Artigas, Emmanouela Repapi, Paul R Burton, Toby Johnson, Adaikalavan Ramasamy, Jing Hua Zhao, Guangju Zhai, Jennifer E Huffman, Veronique Vitart, Eva Albrecht, Wilmar Igl, Anna-Liisa Hartikainen, Anneli Pouta, Gemma Cadby, Jennie Hui, Lyle J Palmer, David Hadley, Wendy L McArdle, Alicja R Rudnicka, Inês Barroso, Ruth J F Loos, Nicholas J Wareham, Massimo Mangino, Nicole Soranzo, Tim D Spector, Sven Gläser, Georg Homuth, Henry Völzke, Panos Deloukas, Raquel Granell, John Henderson, Ivica Grkovic, Stipan Jankovic, Lina Zgaga, Ozren Polašek, Igor Rudan, Alan F Wright, Harry Campbell, Sarah H Wild, James F Wilson, Joachim Heinrich, Medea Imboden, Nicole M Probst-Hensch, Ulf Gyllensten, Åsa Johansson, Ghazal Zaboli, Linda Mustelin, Taina Rantanen, Ida Surakka, Jaakko Kaprio, Marjo-Riitta Jarvelin, Caroline Hayward, David M Evans, Beate Koch, Arthur William Musk, Paul Elliott, David P Strachan, Martin D Tobin, Ian Sayers, Ian P Hall, SpiroMeta Consortium
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19382 (2011)
Lung function measures are heritable traits that predict population morbidity and mortality and are essential for the diagnosis of chronic obstructive pulmonary disease (COPD). Variations in many genes have been reported to affect these traits, but a
Externí odkaz:
https://doaj.org/article/4599c74504394553addcb29274fceaa1
Autor:
Bernhard M Kaess, Maciej Tomaszewski, Peter S Braund, Klaus Stark, Suzanne Rafelt, Marcus Fischer, Robert Hardwick, Christopher P Nelson, Radoslaw Debiec, Fritz Huber, Werner Kremer, Hans Robert Kalbitzer, Lynda M Rose, Daniel I Chasman, Jemma Hopewell, Robert Clarke, Paul R Burton, Martin D Tobin, Christian Hengstenberg, Nilesh J Samani
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14529 (2011)
HDL cholesterol (HDL-C) is an established marker of cardiovascular risk with significant genetic determination. However, HDL particles are not homogenous, and refined HDL phenotyping may improve insight into regulation of HDL metabolism. We therefore
Externí odkaz:
https://doaj.org/article/db13f5b5561b4858acda2f46a8bfd058
Publikováno v:
PLoS Medicine, Vol 5, Iss 8, p e177 (2008)
Externí odkaz:
https://doaj.org/article/705b5fa7b01b4f5f95f5785c483cac12
Autor:
Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William De Nardo, Stacey N. Keenan, Paula M. Miotto, Hamzeh Karimkhanloo, Cheng Huang, Ralf B. Schittenhelm, Anthony S. Don, Andrew Ryan, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Benjamin L. Parker, Matthew J. Watt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Non-alcoholic steatohepatitis (NASH) and type 2 diabetes are closely linked, but the connecting pathophysiological mechanisms are incompletely understood. Here the authors identify arylsulfatase A as a NASH-induced hepatokine that inhibits hepatic ly
Externí odkaz:
https://doaj.org/article/0e3d36630f204b8aa3e526d0e0913eb1
Autor:
Jacqueline Bayliss, Geraldine J. Ooi, William De Nardo, Yazmin Johari Halim Shah, Magdalene K. Montgomery, Catriona McLean, William Kemp, Stuart K. Roberts, Wendy A. Brown, Paul R. Burton, Matthew J. Watt
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Ectodysplasin A (EDA) was recently identified as a liver-secreted protein that is increased in the liver and plasma of obese mice and causes skeletal muscle insulin resistance. We assessed if liver and plasma EDA is associated with worsening non-alco
Externí odkaz:
https://doaj.org/article/25a873eb0dba42f9920526140db6b0cf
Autor:
Chiara Chadwick, Paul R. Burton, Dianne Brown, Jennifer F. Holland, Angus Campbell, Jenifer Cottrell, Andrew D. MacCormick, Ian Caterson, Wendy A. Brown
Publikováno v:
Obesity Surgery. 33:1160-1169
Purpose This study aims to determine if the hospital efficiency, safety and health outcomes are equal in patients who receive bariatric surgery in government-funded hospitals (GFH) versus privately funded hospitals (PFH). Materials and Methods This i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6a2c4e9f54b00f20b32b44e6fd0532a
https://doi.org/10.1007/s11695-023-06489-3
https://doi.org/10.1007/s11695-023-06489-3
Autor:
Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William de Nardo, Stacey N. Keenan, Marziyeh Anari, Amanuiel Z. Taddese, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Paul Gregorevic, Craig A. Goodman, Kevin I. Watt, Matthew J. Watt
Publikováno v:
Diabetes. 72:715-727
Non-alcoholic fatty liver disease (NAFLD) and impaired glycaemic control are closely linked, however, the pathophysiological mechanisms underpinning this bidirectional relationship remain unresolved. The high secretory capacity of the liver and impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fb2002fab7eac62bf27db230f50f5d
https://doi.org/10.2337/db22-0590
https://doi.org/10.2337/db22-0590
Autor:
Paul R. Burton
Publikováno v:
EClinicalMedicine, Vol 28, Iss , Pp 100606- (2020)
Externí odkaz:
https://doaj.org/article/2406c5eaa9e7402d8495d52ea8ba39a5
Autor:
Madeleine J. Murtagh, Mwenza T. Blell, Olly W. Butters, Lorraine Cowley, Edward S. Dove, Alissa Goodman, Rebecca L. Griggs, Alison Hall, Nina Hallowell, Meena Kumari, Massimo Mangino, Barbara Maughan, Melinda C. Mills, Joel T. Minion, Tom Murphy, Gillian Prior, Matthew Suderman, Susan M. Ring, Nina T. Rogers, Stephanie J. Roberts, Catherine Van der Straeten, Will Viney, Deborah Wiltshire, Andrew Wong, Neil Walker, Paul R. Burton
Publikováno v:
Human Genomics, Vol 12, Iss 1, Pp 1-12 (2018)
Abstract Background Genomic and biosocial research data about individuals is rapidly proliferating, bringing the potential for novel opportunities for data integration and use. The scale, pace and novelty of these applications raise a number of urgen
Externí odkaz:
https://doaj.org/article/733decf5a9504990937c04bf2531d84a