Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Paul R, Gigante"'
Autor:
Andrew F Ducruet, Brad E Zacharia, Sergey A Sosunov, Paul R Gigante, Mason L Yeh, Justin W Gorski, Marc L Otten, Richard Y Hwang, Peter A DeRosa, Zachary L Hickman, Paulina Sergot, E Sander Connolly
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38664 (2012)
The restoration of blood-flow following cerebral ischemia incites a series of deleterious cascades that exacerbate neuronal injury. Pharmacologic inhibition of the C3a-receptor ameliorates cerebral injury by attenuating post-ischemic inflammation. Re
Externí odkaz:
https://doaj.org/article/86b13f22d9e74f47a810f87d721e7612
Autor:
Michael G. Vitale, Toni S. Pearson, Richard C. E. Anderson, David P. Roye, Joshua E. Hyman, Claudia A. Chiriboga, Genevieve Chirelstein, Benjamin D. Roye, Joseph Dutkowsky, Patricia A. Ryan, Elizabeth J. Fontana, Dean Morgan, Heakyung Kim, Paul R. Gigante, Samuel S. Bruce, Michael M. McDowell
Publikováno v:
Journal of Neurosurgery: Pediatrics. 12:588-594
Object Randomized clinical trials have established that lumbar selective dorsal rhizotomy (SDR) reduces lower-extremity tone and improves functional outcome in children with spastic cerebral palsy. Significant data exist to support a secondary effect
Autor:
E. Sander Connolly, Andrew F. Ducruet, Matthew Piazza, Amanda M. Carpenter, Paul R. Gigante, Samuel S. Bruce, Rajeev Deb-Sen, Geoffrey Appelboom, Philip M. Meyers, Christopher P. Kellner, Michael A Kellner, Kerry A. Vaughan, Brian Y. Hwang
Publikováno v:
Journal of Neurosurgery. 116:185-192
Object Intraventricular hemorrhage (IVH) associated with intracerebral hemorrhage (ICH) is an independent predictor of poor outcome. Clinical methods for evaluating IVH, however, are not well established. This study sought to determine the best IVH g
Autor:
Steven R. Isaacson, Mark A. Attiah, Paul R. Gigante, Raqeeb Haque, Teresa Wojtasiewicz, Michael B. Sisti, Brendan Huang
Publikováno v:
Journal of Neurosurgery. 115:917-923
Object The goal of this article was to show that a combination of facial nerve–sparing microsurgical resection and Gamma Knife surgery (GKS) for expansion of any residual tumor can preserve good facial nerve function in patients with recurrent vest
Publikováno v:
Journal of Neurosurgery: Pediatrics. 8:363-366
Os odontoideum is a common cause of atlantoaxial instability in the pediatric population. The authors present the cases of 2 patients whose initial clinical presentation and MR imaging findings were suggestive of an intramedullary neoplasm, but whose
Autor:
Andrew F. Ducruet, Justin W. Gorski, Gregory H. Cohen, E. Sander Connolly, Peter A. DeRosa, Brad E. Zacharia, Paul R. Gigante, Sergey A. Sosunov, Mason L. Yeh
Publikováno v:
Translational Stroke Research. 2:588-599
The complement cascade is a critical mediator of the inflammatory response following cerebral ischemia. Recent work has demonstrated that genetic-deficiency of Mannose-binding lectin(MBL) ameliorates reperfusion injury and improves outcome in the acu
Autor:
Robert R. Goodman, Paul R. Gigante
Publikováno v:
Current Neurology and Neuroscience Reports. 11:404-408
The mainstay of epilepsy surgery is the resection of a presumed seizure focus or disruption of seizure propagation pathways. These approaches cannot be applied to all patients with medically refractory epilepsy (MRE). Since 1997, vagus nerve stimulat
Autor:
Ivan S. Kotchetkov, Amit Ayer, Geoffrey Appelboom, Raqeeb Haque, Brian Y. Hwang, Christopher P. Kellner, E. Sander Connolly, Michael A Kellner, Paul R. Gigante
Publikováno v:
Cerebrovascular Diseases. 31:211-222
Intracerebral hemorrhage (ICH) is associated with higher mortality and morbidity than any other form of stroke. However, there currently are no treatments proven to improve outcomes after ICH, and therefore, new effective therapies are urgently neede
Autor:
Brian Y. Hwang, Paul R. Gigante, Andrew F. Ducruet, Raqeeb Haque, Christopher P. Kellner, Ivan S. Kotchetkov, Eric J. Heyer, Robert A. Solomon, E. Sander Connolly
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 82:247-253
Background Up to 28% of patients undergoing carotid endarterectomy (CEA) are estimated to experience neurocognitive dysfunction following surgery. The complement cascade plays a central role in ischaemia-reperfusion injury. The authors investigated t
Autor:
Brian Y. Hwang, Christopher P. Kellner, Michael A Kellner, Amanda M. Carpenter, Paul R. Gigante, E. Sander Connolly, Geoffrey Appelboom
Publikováno v:
Neurocritical Care. 13:141-151
Intracerebral hemorrhage (ICH) carries higher risk of long-term disability and mortality than any other form of stroke. Despite greater understanding of ICH pathophysiology, treatment options for this devastating condition remain limited. Moreover, a