Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Paul Q. Patek"'
Autor:
Darren J. Park, Paul Q. Patek
Publikováno v:
BioTechniques, Vol 24, Iss 4, Pp 558-560 (1998)
Externí odkaz:
https://doaj.org/article/af682ccf55a549f0a4c8591f9e0aa10e
Autor:
Heinz Gert de Couet, James T. Douglas, Osler A. Andres, Paul Q. Patek, Sandro Jube, Chad B. Walton, Dulal Borthakur, Ana Blossom H. Inos
Publikováno v:
Vaccine. 26:4396-4402
The aim of this research was to identify subunit immunogens that can generate enhanced CD8 T cell and TH1 responses against Mycobacterium tuberculosis. A genomic comparison of the M. tuberculosis H(37)R(V) and M. bovis BCG identified 61 proteins that
Autor:
Carl Y. Sasaki, Paul Q. Patek
Publikováno v:
International Journal of Cancer. 81:141-147
Using the tumor necrosis factor (TNF)-resistant cell line B/CN and an anchorage-independent variant, 10ME, we have shown a relationship between transformation and sensitivity to TNF. Here, we report a role for protein tyrosine phosphorylation in expr
Autor:
Paul Q. Patek, Carl Y. Sasaki
Publikováno v:
International Journal of Immunopharmacology. 16:301-309
A spleen cell-elaborated factor which inhibits both TNF and natural cytotoxic cell lytic activity has been described. Production of this factor is dependent on prostaglandins, and inhibitory activity is abrogated by protein synthesis inhibitors. Furt
Autor:
Paul Q. Patek, Darren J. Park
Publikováno v:
BioTechniques. 24:558-560
Autor:
Carl Y. Sasaki, Paul Q. Patek
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 210(1)
Certain cytokines activate pathways involving protein phosphorylation. Serine and threonine phosphorylation are most common, whereas tyrosine phosphorylation is a rare post-translational event, accounting for a very small percentage of phosphorylated
Autor:
Neil M. Matsui, Paul Q. Patek
Publikováno v:
Cellular immunology. 154(1)
Natural cytotoxic (NC) activity is mediated by a cell-associated form of TNF-alpha. Here, we have characterized the NC-like properties of cloned murine transformed B cell lines. Several B cell lines cause the lysis of NC/TNF-alpha-susceptible target
Publikováno v:
International Journal of Cancer. 24:624-628
Data are presented on the effects of retinoic acid (RA) treatment on the in vivo growth of tumors in two mouse strains. Inhibition of tumor growth as a result of systemic RA injection was observed in three out of seven tumor models. Using adult thyme
Autor:
John Leslie Collins, Paul Q. Patek
Publikováno v:
Cellular Immunology. 116:240-249
Publikováno v:
The Journal of Experimental Medicine
Detailed analysis of the natural killer (NK) activity directed at nontumorigenic cell lines and their transformed tumorigenic derivatives has revealed a paradox. On the one hand, a correlation has been found between the tumorigenic potential of chemi