Zobrazeno 1 - 10
of 439
pro vyhledávání: '"Paul Proost"'
Autor:
Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Estefania Ugarte-Berzal, Jennifer Vandooren, Erik Martens, Mieke Gouwy, Eva Ganseman, Jo Van Damme, Patrick Matthys, Jan Jeroen Vranckx, Paul Proost, Ghislain Opdenakker
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
SDF-1/CXCL12 is a unique chemotactic factor with multiple functions on various types of precursor cells, all carrying the cognate receptor CXCR4. Whereas individual biological functions of SDF-1/CXCL12 have been well documented, practical application
Externí odkaz:
https://doaj.org/article/a3beb009fdca434c94d95233677ef312
Autor:
Luna Dillemans, Karen Yu, Alexandra De Zutter, Sam Noppen, Mieke Gouwy, Nele Berghmans, Lisa Verhallen, Mirre De Bondt, Lotte Vanbrabant, Stef Brusselmans, Erik Martens, Dominique Schols, Patrick Verschueren, Mette M. Rosenkilde, Pedro Elias Marques, Sofie Struyf, Paul Proost
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Interferon-γ-inducible protein of 10 kDa (IP-10/CXCL10) is a dual-function CXC chemokine that coordinates chemotaxis of activated T cells and natural killer (NK) cells via interaction with its G protein-coupled receptor (GPCR), C
Externí odkaz:
https://doaj.org/article/632073f48a4041208b11f2b4ff94603b
Autor:
Sophie Toya, Sofie Struyf, Luis Huerta, Peter Morris, Elizabeth Gavioli, Enrico Maria Minnella, Maria Candida Cesta, Marcello Allegretti, Paul Proost
Publikováno v:
European Respiratory Review, Vol 33, Iss 173 (2024)
Acute respiratory distress syndrome (ARDS) is a severe form of acute respiratory failure characterised by extensive inflammatory injury to the alveolocapillary barrier leading to alveolar oedema, impaired gas exchange and, ultimately, hypoxaemia nece
Externí odkaz:
https://doaj.org/article/721673d66d084e9fb4f1a041b1d1d1b4
Autor:
Frederik Staels, Leoni Bücken, Leana De Vuyst, Mathijs Willemsen, Erika Van Nieuwenhove, Margaux Gerbaux, Julika Neumann, Vanshika Malviya, Lize Van Meerbeeck, Jeason Haughton, Laura Seldeslachts, Mieke Gouwy, Kimberly Martinod, Greetje Vande Velde, Paul Proost, Lidia Yshii, Susan Schlenner, Rik Schrijvers, Adrian Liston, Stephanie Humblet-Baron
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recently, OTULIN haploinsufficiency was linked to enhanced susceptibility to Staphylococcus aureus infections accompanied by local necrosis and systemic inflammation. The pathogenesis observed in haploinsufficient patients differs from the hyperinfla
Externí odkaz:
https://doaj.org/article/5abaa29f9c754698bb267d4fe1544942
Autor:
Vivian Louise Soares Oliveira, Celso Martins Queiroz-Junior, Delphine Hoorelbeke, Felipe Rocha da Silva Santos, Ian de Meira Chaves, Mauro Martins Teixeira, Remo de Castro Russo, Paul Proost, Vivian Vasconcelos Costa, Sofie Struyf, Flávio Almeida Amaral
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPulmonary diseases represent a significant burden to patients and the healthcare system and are one of the leading causes of mortality worldwide. Particularly, the COVID-19 pandemic has had a profound global impact, affecting public healt
Externí odkaz:
https://doaj.org/article/ce4cb6897f284049b9158aa3ae40ddb0
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
BCR::ABL1 negative myeloproliferative neoplasms (MPNs) form a distinct group of hematologic malignancies characterized by sustained proliferation of cells from multiple myeloid lineages. With a median survival of 16-35 months in patients with high-ri
Externí odkaz:
https://doaj.org/article/9b762eecdb5041ae991b86ec4af8d1a4
Autor:
Majid Askaripour, Hamid Najafipour, Shadan Saberi, Saleh Yazdani, Saeideh Jafarinejad-Farsangi, Soodeh Rajabi, Elham Jafari, Paul Proost, Sofie Struyf, Fariba Poosti
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 11, Pp 1317-1325 (2022)
Objective(s): Chronic kidney disease (CKD), accompanied by renal dysfunction, fibrosis, and apoptosis, is highly prevalent in postmenopausal women. We tested the hypothesis that isoflavone daidzein may ameliorate renal dysfunction and fibrosis throug
Externí odkaz:
https://doaj.org/article/2ffd09b61f9a46dda0627beeb942312c
Autor:
Bruna M. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camilla M. Silva, Juliana C. Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M.S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C.M. Cebinelli, Naira L. Bibo, Daniel M. Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Andrea Aramini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://doaj.org/article/a119f5892a0d43a4859a59ccd6f0ea4d
Autor:
Karen Yu, Luna Dillemans, Mieke Gouwy, Helena Bessa, Mieke Metzemaekers, Erik Martens, Patrick Matthys, Xavier Bossuyt, Patrick Verschueren, Carine Wouters, Lien De Somer, Paul Proost
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPeptidylarginine deiminases (PADs) mediate citrullination, an irreversible posttranslational modification that converts arginine to citrulline residues in proteins. Rheumatoid arthritis (RA) is characterized by unique autoantibodies that
Externí odkaz:
https://doaj.org/article/9ca117eb2c8840c6a6bb1c642c7ab377
Autor:
Pedro E. Marques, Sofie Vandendriessche, Thiago H.C. deOliveira, Helena Crijns, Mateus E. Lopes, Marfa Blanter, Sara Schuermans, Karen Yu, Fariba Poosti, Vincent Vanheule, Rik Janssens, Daiane Boff, Andreas J. Kungl, Gustavo B. Menezes, Mauro M. Teixeira, Paul Proost
Publikováno v:
Hepatology Communications, Vol 5, Iss 10, Pp 1737-1754 (2021)
Hepatic cell death occurs in response to diverse stimuli such as chemical and physical damage. The exposure of intracellular contents such as DNA during necrosis induces a severe inflammatory response that has yet to be fully explored therapeutically
Externí odkaz:
https://doaj.org/article/fa45650057184333ad09c0075a73e842