Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Paul P. M. Schnetkamp"'
Publikováno v:
Cell Calcium. 74:61-72
K+-dependent Na+-Ca2+ exchangers (NCKXs) play an important role in Ca2+ homeostasis in many tissues. NCKX proteins are bi-directional plasma membrane Ca2+-transporters which utilize the inward Na+ and outward K+ gradients to move Ca2+ ions into and o
Publikováno v:
Cell Calcium. 74:187-197
K+-dependent Na+-Ca2+ exchangers (NCKXs) belong to Ca2+/cation antiporter gene superfamily. NCKX proteins play an important role in Ca2+ homeostasis and are bi-directional plasma membrane Ca2+-transporters which utilize the inward Na+ and outward K+
Autor:
Robert J. Winkfein, Tatiana P. Rogasevskaia, Paul P. M. Schnetkamp, Ali H. Jalloul, Frank Visser, Robert T. Szerencsei
Publikováno v:
Pigment Cell & Melanoma Research. 32:55-67
NCKX5 is a bidirectional K+ -dependent Na+ -Ca2+ exchanger, which belongs to the SLC24A gene family. In particular, the A111T mutation of NCKX5 has been associated with reduced pigmentation in European populations. In contrast to other NCKX isoforms,
ATP triggers a robust intracellular [Ca2+]-mediated signalling pathway in human synovial fibroblasts
Autor:
Robert T. Szerencsei, Darrell D. Belke, Wayne R. Giles, T. Y. Kim, Paul P. M. Schnetkamp, Colleen S. Kondo, Kenneth W. Spitzer, Ali H. Jalloul, Umberto Banderali, Robert B. Clark
Publikováno v:
Experimental Physiology. 103:1101-1122
New findings What is the central question of this study? What are the main [Ca2+ ]i signalling pathways activated by ATP in human synovial fibroblasts? What is the main finding and its importance? In human synovial fibroblasts ATP acts through a link
Publikováno v:
Cell calcium. 86
K
Publikováno v:
Biochemistry. 55:6445-6455
NCKX1–5 are proteins involved in K+-dependent Na+/Ca2+ exchange in various signal tissues. Here we present a homology model of NCKX2 based on the crystal structure of the NCX_Mj transporter found in Methanoccocus jannaschii. Molecular dynamics simu
Publikováno v:
Biochemistry. 55:2704-2712
The SLC24 gene family encodes K(+)-dependent Na(+)-Ca(2+) exchangers or NCKX proteins. The NCKX4 and NCKX5 isoforms have been shown to be important for pigmentation, and single nucleotide polymorphism (SNP) in both alleles of the SLC24a5 gene is the
Publikováno v:
Cell Calcium. 59:1-11
The Solute Carrier Family 24 (SLC24) belongs to the CaCA super family of Ca(2+)/cation antiporters and codes for five different K(+)- dependent Na(+)- Ca(2+) exchangers (NCKX1-5). NCKX proteins play a critical role in Ca(2+) homeostasis in a wide var
Publikováno v:
Cell Calcium. 86:102153
K+-dependent Na+/Ca2+ exchanger proteins (NCKX1-5) of the SLC24 gene family play important roles in a wide range of biological processes including but not limited to rod and cone photoreceptor vision, olfaction, enamel formation and skin pigmentation
Publikováno v:
Cell calcium. 74
K