Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Paul P. Leyssac"'
Autor:
Paul P. Leyssac, Charlotte Mehlin Sorensen, Ole Skøtt, Max Salomonsson, Niels-Henrik Holstein-Rathlou
Publikováno v:
University of Copenhagen
Previous experiments from our laboratory showed that longer-lasting reductions in renal perfusion pressure (RPP) are associated with a gradual decrease in renal blood flow (RBF) that can be abolished by clamping plasma ANG II concentration ([ANG II])
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 285:R329-R338
The aim of the study was to investigate mechanisms underlying the downregulation of renal blood flow (RBF) after a prolonged reduction in renal perfusion pressure (RPP) in adult spontaneously hypertensive rats (SHR). We tested the effect on the RBF r
Autor:
Ole Torffvit, Paul P. Leyssac, Anne-Lise Kamper, Niels-Henrik Holstein-Rathlou, Per E. Jørgensen, Svend Strandgaard, Steen Seier Poulsen
Publikováno v:
Nephron. 79:167-172
Tamm-Horsfall protein (THP) and epidermal growth factor (EGF) are both synthesized by tubular cells in the distal part of the nephron and excreted with the urine. The present study examines the urinary excretion rates of the two peptides in relation
Publikováno v:
Hypertension. 30:975-983
Abstract The Dahl salt-sensitive (Dahl S) rat develops hypertension and renal injuries when challenged with a high salt diet and has been considered to be a model of chronic renal failure. Renal injuries appear very early in life compared with the sp
Autor:
Paul P. Leyssac, Inger Plum, Svend Strandgaard, Niels Vidiendal Olsen, Michael H. Olsen, Jan Bonde, Inge Lis Kanstrup
Publikováno v:
British Journal of Clinical Pharmacology. 43:509-520
AIMS The purpose of the present study was to define the dose-response relationship between exogenous dopamine and systemic haemodynamics, renal haemodynamics, and renal excretory function at infusion rates in the range 0 to 12.5 microg kg(-1) min(-1)
Publikováno v:
American Journal of Kidney Diseases. 28:822-831
The influence of angiotensin-converting enzyme (ACE) inhibition on renal tubular function in progressive chronic nephropathy was investigated in 69 patients by the lithium clearance (C(Li)) method. Studies were done repeatedly for up to 2 years durin
Publikováno v:
American Journal of Hypertension. 5:423-430
In order to study the influence of angiotensin converting enzyme (ACE) inhibition on the progression of chronic nephropathy, 70 patients with a median glomerular filtration rate (GFR) of 15 (range, 6 to 54) mL/min/1.73 m2 were randomized in an open s
Autor:
Niels Vidiendal Olsen, Niels Fogh-Andersen, Paul P. Leyssac, Jesper Melchior Hansen, S. D. Ladefoged
Publikováno v:
Clinical Science. 78:503-507
1. Using the renal clearance of lithium (CLi) as an index of proximal tubular outflow of sodium and water, together with simultaneous measurements of effective renal plasma flow, glomerular filtration rate (GFR) and sodium clearance (CNa), renal func
Publikováno v:
Europe PubMed Central
Inconsistencies in previous reports regarding changes in early distal NaCl concentration (EDNaCl) and renin secretion during osmotic diuresis motivated our reinvestigation. After intravenous infusion of 10% mannitol, EDNaClfell from 42.6 to 34.2 mM.