Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Paul P. Gardner"'
Autor:
Lesley Sitter, Marion Schoof, Travis R. Glare, Murray P. Cox, Peter C. Fineran, Paul P. Gardner, Mark R. H. Hurst
Publikováno v:
MicrobiologyOpen, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract A soil bacterium in the Serratia genus, carrying a 153 kb conjugative amber disease‐associated plasmid (pADAP), is commercially exploited for population control of the New Zealand endemic pest beetle Costelytra giveni (Coleoptera: Scarabae
Externí odkaz:
https://doaj.org/article/5a610a7efe55480faa75a0c810a6675f
Publikováno v:
PeerJ, Vol 11, p e14969 (2023)
Ribosome-targeting antibiotics comprise over half of antibiotics used in medicine, but our fundamental knowledge of their binding sites is derived primarily from ribosome structures of non-pathogenic species. These include Thermus thermophilus, Deino
Externí odkaz:
https://doaj.org/article/0883e7ddfb124f4fab25a89885e0f905
Autor:
Paul P. Gardner, James M. Paterson, Stephanie McGimpsey, Fatemeh Ashari-Ghomi, Sinan U. Umu, Aleksandra Pawlik, Alex Gavryushkin, Michael A. Black
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Computational biology provides software tools for testing and making inferences about biological data. In the face of increasing volumes of data, heuristic methods that trade software speed for accuracy may be employed. We have st
Externí odkaz:
https://doaj.org/article/cb3ae0b361684e1183833a1f72d4178c
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-8 (2021)
Abstract Most research articles presenting new data analysis methods claim that “the new method performs better than existing methods,” but the veracity of such statements is questionable. Our manuscript discusses and illustrates consequences of
Externí odkaz:
https://doaj.org/article/af463957588640b9954e81012da31227
Autor:
Lukas M. Weber, Wouter Saelens, Robrecht Cannoodt, Charlotte Soneson, Alexander Hapfelmeier, Paul P. Gardner, Anne-Laure Boulesteix, Yvan Saeys, Mark D. Robinson
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract In computational biology and other sciences, researchers are frequently faced with a choice between several computational methods for performing data analyses. Benchmarking studies aim to rigorously compare the performance of different metho
Externí odkaz:
https://doaj.org/article/76f436dd7d284cbb88071898bffb5254
Autor:
Chen Wu, Melissa D. Jordan, Richard D. Newcomb, Neil J. Gemmell, Sarah Bank, Karen Meusemann, Peter K. Dearden, Elizabeth J. Duncan, Sefanie Grosser, Kim Rutherford, Paul P. Gardner, Ross N. Crowhurst, Bernd Steinwender, Leah K. Tooman, Mark I. Stevens, Thomas R. Buckley
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-19 (2017)
Abstract Background The New Zealand collembolan genus Holacanthella contains the largest species of springtails (Collembola) in the world. Using Illumina technology we have sequenced and assembled a draft genome and transcriptome from Holacanthella d
Externí odkaz:
https://doaj.org/article/3b45180332e64ddb87316d0d54587fef
Autor:
Paul P. Gardner, Renee J. Watson, Xochitl C. Morgan, Jenny L. Draper, Robert D. Finn, Sergio E. Morales, Matthew B. Stott
Publikováno v:
PeerJ, Vol 7, p e6160 (2019)
Metagenomic and meta-barcode DNA sequencing has rapidly become a widely-used technique for investigating a range of questions, particularly related to health and environmental monitoring. There has also been a proliferation of bioinformatic tools for
Externí odkaz:
https://doaj.org/article/2c2f0a45eb2e44b987dd2646c8077425
Autor:
Xiaoyun Ren, David A. Eccles, Gabrielle A. Greig, Jane Clapham, Nicole E. Wheeler, Stinus Lindgreen, Paul P. Gardner, Joanna K. MacKichan
Publikováno v:
mSystems, Vol 2, Iss 6 (2017)
ABSTRACT Neisseria meningitidis (meningococcus) can cause meningococcal disease, a rapidly progressing and often fatal disease that can occur in previously healthy children. Meningococci are found in healthy carriers, where they reside in the nasopha
Externí odkaz:
https://doaj.org/article/8bb1289837d14ce8a488114c57fb30b3
Autor:
Fatemeh A. Ghomi, Gemma C. Langridge, Amy K. Cain, Christine Boinett, Moataz Abd El Ghany, Derek J. Pickard, Robert A. Kingsley, Nicholas R. Thomson, Julian Parkhill, Paul P. Gardner, Lars Barquist
The Enterobacteriaceae are a scientifically and medically important clade of bacteria, containing the gut commensal and model organismEscherichia coli, as well as several major human pathogens including multiple serovars ofSalmonella entericaandKlebs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd093059557d325f85953a22b45e98fc
https://doi.org/10.1101/2022.10.20.512852
https://doi.org/10.1101/2022.10.20.512852
Publikováno v:
Nature Protocols. 16:4382-4418
We recently developed a high-throughput functional genomics approach, named 'SorTn-seq', to identify factors affecting expression of any gene of interest in bacteria. Our approach facilitates high-throughput screening of complex mutant pools, a task