Identification of clustered microRNAs using an ab initio prediction method

Autor: Brownstein Michael J, Pfeffer Sébastien, Aravin Alexei, Landgraf Pablo, Paul Nicodème, Sewer Alain, Tuschl Thomas, van Nimwegen Erik, Zavolan Mihaela

Publikováno v: BMC Bioinformatics, Vol 6, Iss 1, p 267 (2005)

Abstract Background MicroRNAs (miRNAs) are endogenous 21 to 23-nucleotide RNA molecules that regulate protein-coding gene expression in plants and animals via the RNA interference pathway. Hundreds of them have been identified in the last five years

Externí odkaz: https://doaj.org/article/8e6e97445c8347f4a8ea6910b0d1df64

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Ubiquitin Receptor Protein UBASH3B Drives Aurora B Recruitment to Mitotic Microtubules

Autor: Krupina, Ksenia, Kleiss, Charlotte, Metzger, Thibaud, Fournane, Sadek, Schmucker, Stephane, Hofmann, Kay, Fischer, Benoit, Paul, Nicodeme, Porter, Iain Malcolm, Raffelsberger, Wolfgang, Poch, Olivier, Swedlow, Jason Reese, Brino, Laurent, Sumara, Izabela

Publikováno v: In Developmental Cell 11 January 2016 36(1):63-78

Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells

Autor: Follain, Gautier, Osmani, Naël, Gensbittel, Valentin, Asokan, Nandini, Larnicol, Annabel, Mercier, Luc, Garcia-Leon, Maria Jesus, Busnelli, Ignacio, Pichot, Angelique, Paul, Nicodème, Carapito, Raphaël, Bahram, Seiamak, Lefebvre, Olivier, Goetz, Jacky G.

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11, pp.13144. ⟨10.1038/s41598-021-92515-2⟩
Scientific Reports, 2021, 11, pp.13144. ⟨10.1038/s41598-021-92515-2⟩

Tumor progression and metastatic dissemination are driven by cell-intrinsic and biomechanical cues that favor the growth of life-threatening secondary tumors. We recently identified pro-metastatic vascular regions with blood flow profiles that are pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c1e09924da1ad2b7a610648863a9a43f
https://doaj.org/article/6130e5f27801400da5a956453d118a77

A mouse model of MSU-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1β as relevant therapy for gout patients

Autor: Mariotte, Alexandre, De Cauwer, Aurore, Po, Chrystelle, Abou-Faycal, Chérine, Pichot, Angélique, Paul, Nicodème, Aouadi, Ismael, Carapito, Raphael, Frisch, Benoit, Macquin, Cécile, Chatelus, Emmanuel, Sibilia, Jean, Armspach, Jean-Paul, Bahram, Seiamak, Georgel, Philippe

Publikováno v: Theranostics

Rationale: The role of Monosodium Urate (MSU) crystals in gout pathophysiology is well described, as is the major impact of IL-1β in the inflammatory reaction that constitutes the hallmark of the disease. However, despite the discovery of the NLRP3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2477ec4a5e8dc457fb77604b3771c6e1
http://europepmc.org/articles/PMC7019178