Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Paul N. Epstein"'
Autor:
Shirong Zheng, Susan Coventry, Lu Cai, David W. Powell, Venkatakrishna R. Jala, Bodduluri Haribabu, Paul N. Epstein
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
In diabetic nephropathy (DN) proinflammatory chemokines and leukocyte infiltration correlate with tubulointerstitial injury and declining renal function. The atypical chemokine receptor ACKR2 is a chemokine scavenger receptor which binds and sequeste
Externí odkaz:
https://doaj.org/article/ab805f31a12c47e497baba9178aa7d45
Autor:
Daniel J. Conklin, Zhengshuai Liu, Qian Lin, Yu Li, Xiaoqing Yan, Xia Fan, Zhifeng Huang, Xiaokun Li, Yi Tan, Genxiang Cai, Zehua Zhao, Lu Cai, Jing-Ya Li, Moosa Mohammadi, Kupper A. Wintergerst, Hongxue Shi, Jia Li, Ming-Hua Zheng, Maiying Kong, Paul N. Epstein
Publikováno v:
Hepatology. 73:2206-2222
BACKGROUND AND AIMS Fibroblast growth factor (FGF) 1 demonstrated protection against nonalcoholic fatty liver disease (NAFLD) in type 2 diabetic and obese mice by an uncertain mechanism. This study investigated the therapeutic activity and mechanism
Autor:
Shirong Zheng, Paul N. Epstein
Publikováno v:
Bio Protoc
CD45 is a pan-leukocyte marker, and CD45 stain is widely used to determine the extent of inflammatory cell infiltration and its association with tissue injury. In this manuscript, we share a reliable immunohistochemistry (IHC) protocol for CD45 stain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e373925bfcc31f6432a71a7b0974caac
https://europepmc.org/articles/PMC8635839/
https://europepmc.org/articles/PMC8635839/
Autor:
Paul N. Epstein, Xiaozhen Dai, Kai Wang, Jing Chen, Yi Tan, Kupper A. Wintergerst, Feixia Shen, Lu Cai
Publikováno v:
Diabetes. 69
Diabetes-induced oxidative stress contributes to endothelial progenitor cells (EPCs) dysfunction and impairs endothelial regeneration. Thus, we tested whether increasing antioxidant protein metallothionein (MT) in EPCs promotes angiogenesis in a hind
Autor:
Paul N. Epstein, Lu Cai, Yi Tan, Genxiang Cai, Yu Li, Jia Li, Zhengshuai Liu, Qian Lin, Kupper A. Wintergerst, Jing-Ya Li
Publikováno v:
Diabetes. 69
Fibroblast growth factor 1 (FGF1) demonstrated protection against nonalcoholic fatty liver disease (NAFLD) in type 2 diabetic (T2D) and obese mice by uncertain mechanism. This study investigated the therapeutic activity and mechanism of a non-mitagen
Autor:
Yi Tan, Chaosheng Lu, Paul N. Epstein, Daniel J. Conklin, Kupper A. Wintergerst, Feixia Shen, Edward C. Carlson, Hairong Liu, Xiaohuan Yuan, Jiawei Fan, Zhongbin Deng, Jianxiang Xu, Jing Chen, Shiyue Sun, Xia Fan, Chengkui Yang, Xiaoqing Yan, Junhong He, Xiaozhen Dai, Kai Wang, Ada Admin
Diabetes-induced oxidative stress is one of the major contributors to dysfunction of endothelial progenitor cells (EPCs) and impaired endothelial regeneration. Thus, we tested whether increasing antioxidant protein metallothionein (MT) in EPCs promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284abf787e5fec1a59cc85e01ee325fa
https://doi.org/10.2337/figshare.12280736
https://doi.org/10.2337/figshare.12280736
Autor:
Kenneth R. Brittian, Andrew A. Gibb, Yuting Zheng, Paul N. Epstein, Jianxun Wang, Bradford G. Hill, Aruni Bhatnagar, Patrick J. Trainor, Steven P. Jones, Michael T. Tseng, Detlef Obal, Kartik Katragadda, Lindsey A. McNally, Shizuka Uchida, Daniel J. Conklin
Publikováno v:
Circulation. 136:2144-2157
Background: Exercise promotes metabolic remodeling in the heart, which is associated with physiological cardiac growth; however, it is not known whether or how physical activity–induced changes in cardiac metabolism cause myocardial remodeling. In
Autor:
Xiaoqing Yan, Lu Cai, Shanshan Zhou, Yan Li, Jian Xiao, Chi Zhang, Kai Wang, Kupper A. Wintergerst, Paul N. Epstein, Junlian Gu, Yang Bai, Xiaozhen Dai, Ying Xin, Qian Lin, Xiaokun Li, Yuehui Wang, Jian Zhang, Michelle T. Barati, Yi Tan, Jun Zeng
Publikováno v:
Diabetes
Cardiac insulin resistance is a key pathogenic factor for diabetic cardiomyopathy (DCM), but the mechanism remains largely unclear. We found that diabetic hearts exhibited decreased phosphorylation of total Akt and isoform Akt2 but not Akt1 in wild-t
Autor:
Jennifer M. Chhoun, Bryon Grove, Shirong Zheng, Donna I. Laturnus, Paul N. Epstein, Edward C. Carlson, Yi Tan
Publikováno v:
The Anatomical Record. 300:560-576
We previously demonstrated that OVE transgenic diabetic mice are susceptible to chronic complications of diabetic nephropathy (DN) including substantial oxidative damage to the renal glomerular filtration barrier (GFB). Importantly, the damage was mi
Autor:
Jianxiang Xu, Xiaoqing Yan, Jiawei Fan, Zhongbin Deng, Hairong Liu, Chaosheng Lu, Xiaohuan Yuan, Paul N. Epstein, Junhong He, Chengkui Yang, Yi Tan, Shiyue Sun, Kai Wang, Kupper A. Wintergerst, Xiaozhen Dai, Edward C. Carlson, Feixia Shen, Jing Chen, Daniel J. Conklin, Xia Fan
Publikováno v:
Diabetes
Diabetes-induced oxidative stress is one of the major contributors to dysfunction of endothelial progenitor cells (EPCs) and impaired endothelial regeneration. Thus, we tested whether increasing antioxidant protein metallothionein (MT) in EPCs promot