Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Paul N, Hopkins"'
Autor:
Mahyar Heydarpour, Wasita W. Parksook, Paul N. Hopkins, Luminita H. Pojoga, Gordon H. Williams, Jonathan S. Williams
Publikováno v:
Journal of Hypertension. 41:723-732
Autor:
Andrea V Haas, Paul N Hopkins, Nancy J Brown, Luminita H Pojoga, Jonathan S Williams, Gail K Adler, Gordon H Williams
Publikováno v:
Endocrine Connections, Vol 8, Iss 6, Pp 634-640 (2019)
There are conflicting data on whether variations of physiologic cortisol levels associated with cardiovascular risk. We hypothesize that prior discordant findings are related to problems associated with varying sample size, techniques for assessing c
Externí odkaz:
https://doaj.org/article/87bc0b6894e74183acdc85cbfd2b1d85
Autor:
Xin Geng, Marguerite R. Irvin, Bertha Hidalgo, Stella Aslibekyan, Vinodh Srinivasasainagendra, Ping An, Alexis C. Frazier-Wood, Hemant K. Tiwari, Tushar Dave, Kathleen Ryan, Jose M. Ordovas, Robert J. Straka, Mary F. Feitosa, Paul N. Hopkins, Ingrid Borecki, Michael A. Province, Braxton D. Mitchell, Donna K. Arnett, Degui Zhi
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 4, Pp 722-729 (2018)
Our understanding of genetic influences on the response of lipids to specific interventions is limited. In this study, we sought to elucidate effects of rare genetic variants on lipid response to a high-fat meal challenge and fenofibrate (FFB) therap
Externí odkaz:
https://doaj.org/article/e0de3fbd7e08430682e45c0f2f26ca3a
Autor:
Caitlin C, Fermoyle, Ryan M, Broxterman, D Taylor, La Salle, Stephen M, Ratchford, Paul N, Hopkins, Russell S, Richardson, Joel D, Trinity
Publikováno v:
J Hypertens
Vascular dysfunction, an independent risk factor for cardiovascular disease, often persists in patients with hypertension, despite improvements in blood pressure control induced by antihypertensive medications.As some of these medications may directl
Autor:
Stella Aslibekyan, Marguerite R. Irvin, Bertha A. Hidalgo, Rodney T. Perry, Elias J. Jeyarajah, Erwin Garcia, Irina Shalaurova, Paul N. Hopkins, Michael A. Province, Hemant K. Tiwari, Jose M. Ordovas, Devin M. Absher, Donna K. Arnett
Publikováno v:
Journal of Nutrition & Intermediary Metabolism, Vol 8, Iss C, Pp 1-7 (2017)
Background: Trimethylamine-N-oxide (TMAO), an atherogenic metabolite species, has emerged as a possible new risk factor for cardiovascular disease. Animal studies have shown that circulating TMAO levels are regulated by genetic and environmental fact
Externí odkaz:
https://doaj.org/article/6f037271917f45cd96871c16b222870d
Autor:
Yao Hu, Toshiko Tanaka, Jingwen Zhu, Weihua Guan, Jason H.Y. Wu, Bruce M. Psaty, Barbara McKnight, Irena B. King, Qi Sun, Melissa Richard, Ani Manichaikul, Alexis C. Frazier-Wood, Edmond K. Kabagambe, Paul N. Hopkins, Jose M. Ordovas, Luigi Ferrucci, Stefania Bandinelli, Donna K. Arnett, Yii-Der I. Chen, Shuang Liang, David S. Siscovick, Michael Y. Tsai, Stephen S. Rich, Myriam Fornage, Frank B. Hu, Eric B. Rimm, Majken K. Jensen, Rozenn N. Lemaitre, Dariush Mozaffarian, Lyn M. Steffen, Andrew P. Morris, Huaixing Li, Xu Lin
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 5, Pp 974-981 (2017)
MUFAs are unsaturated FAs with one double bond and are derived from endogenous synthesis and dietary intake. Accumulating evidence has suggested that plasma and erythrocyte MUFA levels are associated with cardiometabolic disorders, including CVD, T2D
Externí odkaz:
https://doaj.org/article/44c9aaa4c707484ead48ec7020a3aff9
Autor:
Latisha Love-Gregory, Aldi T. Kraja, Fiona Allum, Stella Aslibekyan, Åsa K. Hedman, Yanan Duan, Ingrid B. Borecki, Donna K. Arnett, Mark I. McCarthy, Panos Deloukas, Jose M. Ordovas, Paul N. Hopkins, Elin Grundberg, Nada A. Abumrad
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 12, Pp 2176-2184 (2016)
Cluster of differentiation 36 (CD36) variants influence fasting lipids and risk of metabolic syndrome, but their impact on postprandial lipids, an independent risk factor for cardiovascular disease, is unclear. We determined the effects of SNPs withi
Externí odkaz:
https://doaj.org/article/881234db04a0440b9de2a8e18f98abf1
Autor:
Samar R. El Khoudary, Qian Zhao, Vidya Venugopal, JoAnn E. Manson, Maria M. Brooks, Nanette Santoro, Dennis M. Black, S. Mitchell Harman, Marcelle I. Cedars, Paul N. Hopkins, Ann E. Kearns, Virginia M. Miller, Hugh S. Taylor, Matthew J. Budoff
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 15 (2019)
Background Heart fats (epicardial and paracardial adipose tissue [PAT]) are greater after menopause. Endogenous estrogen may regulate these fat depots. We evaluated the differential effects of hormone therapy formulations on heart fat accumulations a
Externí odkaz:
https://doaj.org/article/9005ef76c0174b0ebf794f48950e1192
Autor:
Xin Geng, Marguerite R. Irvin, Bertha Hidalgo, Stella Aslibekyan, Vinodh Srinivasasainagendra, Ping An, Alexis C. Frazier-Wood, Hemant K. Tiwari, Tushar Dave, Kathleen Ryan, Jose M. Ordovas, Robert J. Straka, Mary F. Feitosa, Paul N. Hopkins, Ingrid Borecki, Michael A. Province, Braxton D. Mitchell, Donna K. Arnett, Degui Zhi
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Background: Associations of both common and rare genetic variants with fasting blood lipids have been extensively studied. However, most of the rare coding variants associated with lipids are population-specific, and exploration of genetic data from
Externí odkaz:
https://doaj.org/article/8d3ba7481f98478aa8a4eefbc54ec41c
Autor:
Wasita W Parksook, Mahyar Heydarpour, Shadi K Gholami, James M Luther, Paul N Hopkins, Luminita H Pojoga, Jonathan S Williams
Publikováno v:
J Clin Endocrinol Metab
Context Salt sensitivity of blood pressure (SSBP) is associated with increased cardiovascular risk, especially in individuals of African descent, although the underlying mechanisms remain obscure. Lysine-specific demethylase 1 (LSD1) is a salt-sensit