Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Paul Meers"'
Publikováno v:
Membrane Fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de2c7df334fb618b5362b7eee53d9605
https://doi.org/10.1201/9780367811525-9
https://doi.org/10.1201/9780367811525-9
Autor:
William Bartos, Maria Jose Pozo, Dominick Panzera, Julianne Davis, Shu Wang, Carol Liu, Jason Orciuolo, Szymon Kutyla, Deepti Mithrananda, Rensa Chen, Paul Meers, Nicole Dziedzic
Lysobacter enzymogenes C3 is a predatory strain of gram-negative gliding bacteria that produces antifungal antibiotics by the polyketide synthetic pathway. Outer membrane vesicles (OMV) are formed as a stress response and can deliver virulence factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e265ab36337dcf9f604687448d03e88
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 22:131-138
Background: The purpose of this study was to investigate the inhalation of a liposomal formulation of amikacin in healthy male volunteers in terms of pulmonary deposition, clearance, and safety following nebulization with a commercial jet nebulizer.
Autor:
Paul Meers, M. Neville, Vladimir Malinin, Steve T. Fisher, Garth A. James, Walter Perkins, R. Kurumunda, G. Sardaryan, C. Mackinson, A. W. Scotto
Publikováno v:
Journal of Antimicrobial Chemotherapy. 61:859-868
Objectives Chronic infections of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients are intractable antibiotic targets because of their biofilm mode of growth. We have investigated the biofilm penetration, mechanism of drug release and i
Publikováno v:
Biophysical Journal. 108(2)
Gram negative bacteria produce small ∼50-200 nm vesicles from their outer membranes. These outer membrane vesicles (OMV) have been implicated in activities such as transmission of virulence factors, horizontal gene transfer and development of biofi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1616:184-195
We present results on using cooperative interactions to shield liposomes by incorporating multiple hydrophobic anchoring sites on polyethylene glycol (PEG) polymers. The hydrophobically-modified PEGs (HMPEGs) are comb-graft polymers with strictly alt
Autor:
Paul Meers
Publikováno v:
Advanced Drug Delivery Reviews. 53:265-272
It has become increasingly evident that tissues utilize specific localization of enzymes to perform certain tasks, often associated with various types of tissue remodeling. The ubiquitous presence of such enzymes, along with their specific localizati
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1419:111-126
The specific activation of liposomes for delivery has been explored by enzyme mediated cleavage of a peptide substrate covalently conjugated to a fusogenic lipid. We have previously shown an elastase sensitive peptide conjugated to 1,2-dioleoyl-sn-gl
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1368(2):171-183
N-acyl phosphatidylethanolamines (NAPEs) are natural lipid components of many organisms. N-acylation of unsaturated phosphatidylethanolamines with a saturated fatty acid converts them from non-lamellar organizing lipids into lamellar organizing, acid
Autor:
Daniel W. Reynolds, Mark H. Kleinman, Paul Meers, Robert A. Reed, Biren K. Joshi, Christopher James Foti, Karen M. Alsante, Venkatramana M. Rao, Steven W. Baertschi, Andreas Abend, Margaret S. Landis, Kim Huynh-Ba
Publikováno v:
AAPS PharmSciTech. 15(1)
The American Association for Pharmaceutical Scientists (AAPS) Workshop on Predicting and Monitoring Impurities in API and Drug Products: Product Development and Regulatory Issues was held on October 13–14, 2012 at the McCormick Place in Chicago, IL