Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Paul McGonigle"'
Publikováno v:
Journal of Human Sport and Exercise, Vol 18, Iss 3 (2023)
The purpose of the present study was to examine the presence and longitudinal trends of relative age effects (RAEs) in prominent Irish youth sports (soccer and Gaelic football) through a combination of cross-sectional, quasi-longitudinal, and longitu
Externí odkaz:
https://doaj.org/article/43fa63d6afd94edf95f11eb541dbe3f4
Publikováno v:
Pharmacology Research & Perspectives, Vol 7, Iss 6, Pp n/a-n/a (2019)
Abstract Monoclonal antibodies (mAbs) have emerged as a major class of therapeutic agents on the market. To date, approximately 80 mAbs have been granted marketing approval. In 2018, 12 new mAbs were approved by the FDA, representing 20% of the total
Externí odkaz:
https://doaj.org/article/7155363f6e954bbd97f1a634f0fab4b8
Publikováno v:
Neurobiology of Stress, Vol 2, Iss C, Pp 73-84 (2015)
Monoaminergic brainstem systems have widespread projections that participate in many central processes and, when dysregulated, contribute to a plethora of neuropsychiatric and neurodegenerative disorders. Synapses are the foundation of these neuronal
Externí odkaz:
https://doaj.org/article/7e9735f241014508a3328f4c30623e66
Publikováno v:
Neurobiology of Stress, Vol 1, Iss C, Pp 33-43 (2015)
Repeated, extreme, or traumatic stressors can elicit pathological effects leading to many negative physical and psychological outcomes. Stressors can precipitate the onset of psychiatric diseases, or exacerbate pre-existing disorders including variou
Externí odkaz:
https://doaj.org/article/7ccefd892de44601af9c3a612200491d
Publikováno v:
Pharmacology Research & Perspectives, Vol 7, Iss 6, Pp n/a-n/a (2019)
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives
Monoclonal antibodies (mAbs) have emerged as a major class of therapeutic agents on the market. To date, approximately 80 mAbs have been granted marketing approval. In 2018, 12 new mAbs were approved by the FDA, representing 20% of the total number o
Publikováno v:
Pharmacological Research. 113:327-331
Autor:
Ariana Myers, Paul McGonigle
Publikováno v:
Current protocols in neuroscienceLITERATURE CITED. 89(1)
This review describes several transgenic mouse models of Alzheimer's disease (AD), a devastating neurodegenerative disorder that causes progressive cognitive decline and is diagnosed postmortem by the presence of extracellular amyloid-β (Aβ) plaque
Publikováno v:
British Journal of Pharmacology. 172:2991-3002
Background and Purpose Store-operated calcium (SOC) channels are thought to play a critical role in immune responses, inflammatory diseases and chronic pain. The aim of this study was to explore the potential role and mechanisms of SOC channels in co
The endocannabinoid (eCB) system plays an important role in the control of mood, and its dysregulation has been implicated in several psychiatric disorders. Targeting the eCB system appears to represent an attractive and novel approach to the treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755242ae1a2decdc5afcf3bea0cca40c
https://europepmc.org/articles/PMC4696509/
https://europepmc.org/articles/PMC4696509/
Autor:
Denise Fairman, Lorayne Jenkins, Danni Liu, Andrew Wood, Paul McGonigle, Ping Li, Seongeun Cho
Publikováno v:
Neurochemistry International. 45:117-127
Oxygen–glucose deprivation (OGD) induced neuron-specific cell death in organotypic hippocampal slice cultures. Neuronal death was first evident in the CA1 region 24 h after the injury as assessed by propidium iodide (PI) labeling, and continued to